CIK: 0001012622
Total reported value
$167.9M
Reporting period: 2025-12-31 · Number of holdings: 22
ORACLE INVESTMENT MANAGEMENT INC disclosed 22 holdings in its latest 13F filing for the period ending 2025-12-31, with total reported value of $167.9M and a quarterly turnover rate of 35.5%.
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Oracle Investment Management INC's disclosed holdings carry a Herfindahl concentration index of 0.480 — mathematically equivalent to about 2 equally-sized positions, well below its 22 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 3.16), with a handful of outsized bets alongside many smaller positions.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 2.5 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 1% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Add WGS
-0.6% $19.2M
Trim TDOC
-49.8% -$3.0M
Trim BHVN
+4.4% -$2.4M
Add ARDX
+24.5% $2.6M
Trim G1110E907
-15.3% -$1.5M
Add PSNL
+47.9% $1.2M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | WGS | Genedx Holdings CORP | Stock-Other | 68.51% | +8.61% | -0.60% | |
| 2 | ARDX | Ardelyx INC | Stock-Other | 6.50% | +1.32% | +24.52% | |
| 3 | BHVN | Biohaven Ltd. | Stock-Other | 5.19% | -1.75% | +4.35% | |
| 4 | TDOC | Teladoc Health, Inc. | Stock-Healthcare | 2.71% | +0.44% | +38.15% | |
| 5 | NVAX 5 12-15-27 | Novavax INC | Stock-Healthcare | 2.40% | +2.40% | NEW | |
| 6 | ✓ | Ardelyx INC | Stock-Other | 2.08% | -0.10% | -5.18% | |
| 7 | QDEL | Quidelortho CORP | Stock-Other | 2.01% | -0.17% | — | |
| 8 | FORA | Forian INC | Stock-Other | 1.72% | -0.20% | — | |
| 9 | PSNL | Personalis INC | Stock-Other | 1.61% | +0.68% | +47.90% | |
| 10 | ✓ | Biohaven LTD | Stock-Other | 1.57% | -1.01% | -15.31% | |
| 11 | TDOC | Teladoc Health INC | Stock-Healthcare | 1.48% | -1.93% | -49.77% | |
| 12 | TSHA | Taysha Gene Therapies INC | Stock-Other | 0.87% | +0.87% | NEW | |
| 13 | CAVA | Cava Group INC | Stock-Consumer Disc | 0.60% | -0.05% | — | |
| 14 | EWTX | Edgewise Therapeutics INC | Stock-Other | 0.57% | +0.57% | NEW | |
| 15 | DAWNGBX | Day One Biopharmaceuticals I | Stock-Other | 0.55% | +0.56% | NEW | |
| 16 | PFE | Pfizer Inc. | Stock-Healthcare | 0.37% | +0.37% | NEW | |
| 17 | ARKG | Ark Genomic Revolution ETF | ETF-Other | 0.34% | +0.34% | NEW | |
| 18 | SGMOQ | Sangamo Therapeutics INC | Stock-Other | 0.26% | -0.16% | +3.09% | |
| 19 | BIIB | Biogen INC | Stock-Healthcare | 0.25% | +0.04% | — | |
| 20 | TEM | Tempus Ai Inc-cl A | Stock-Healthcare | 0.23% | +0.23% | NEW | |
| 21 | TSLA | Tesla INC | Stock-Consumer Disc | 0.13% | -0.01% | — | |
| 22 | HTZ | Hertz Global Hldgs INC | Stock-Other | 0.05% | +0.05% | NEW |
Performance for Q3 2026
+8.3%
Performance Last 4 Quarters
-19.2%
Based on 86% of reported portfolio value with available pricing
| Period | Holdings | Total value | Stability | Top holdings |
|---|---|---|---|---|
| 2025-12-31 | 22 | $167.9M | 36 | |
| 2025-09-30 | 20 | $160.1M | 66 | |
| 2025-06-30 | 14 | $145.8M | 0 | |
| 2025-03-31 | 17 | $198.2M | 100 | |
| 2024-12-31 | 19 | $183.7M | 0 | |
| 2024-09-30 | 22 | $166.9M | 0 | |
| 2024-06-30 | 22 | $107.2M | 0 | |
| 2024-03-31 | 27 | $150.5M | 0 | |
| 2023-12-31 | 26 | $164.4M | 0 | |
| 2023-09-30 | 23 | $325.8M | 0 | 1219798269404D3G1110E |
| 2023-06-30 | 29 | $135.7M | 0 | |
| 2023-03-31 | 27 | $103.3M | 0 | |
| 2022-12-31 | 24 | $119.9M | 0 | |
| 2022-09-30 | 24 | $176.0M | 0 | |
| 2022-06-30 | 27 | $329.2M | 0 | |
| 2022-03-31 | 32 | $505.7M | 0 | |
| 2021-12-31 | 32 | $703.7M | 0 | |
| 2021-09-30 | 40 | $803.2M | 0 | |
| 2021-06-30 | 29 | $725.6M | 30 | |
| 2021-03-31 | 28 | $667.8M | 47 | |
| 2020-12-31 | 22 | $798.0M | 35 | |
| 2020-09-30 | 20 | $758.8M | 16 | |
| 2020-06-30 | 19 | $788.2M | 84 | |
| 2020-03-31 | 19 | $336.6M | 68 | |
| 2019-12-31 | 20 | $532.6M | 34 | |
| 2019-09-30 | 21 | $406.6M | 19 | |
| 2019-06-30 | 18 | $464.9M | 16 | |
| 2019-03-31 | 18 | $470.0M | 65 | |
| 2018-12-31 | 19 | $322.4M | 50 | |
| 2018-09-30 | 19 | $456.8M | 39 | |
| 2018-06-30 | 21 | $413.7M | 82 | |
| 2018-03-31 | 21 | $412.7M | 37 | |
| 2017-12-31 | 24 | $503.3M | 32 | |
| 2017-09-30 | 22 | $609.7M | 34 | |
| 2017-06-30 | 20 | $632.9M | 51 | |
| 2017-03-31 | 21 | $641.4M | 50 | |
| 2016-12-31 | 17 | $602.9M | 28 | |
| 2016-09-30 | 17 | $648.9M | 47 | |
| 2016-06-30 | 19 | $429.6M | 21 | |
| 2016-03-31 | 20 | $384.6M | 46 | |
| 2015-12-31 | 23 | $577.1M | 33 | |
| 2015-09-30 | 25 | $488.9M | 52 | |
| 2015-06-30 | 27 | $824.2M | 28 | |
| 2015-03-31 | 28 | $788.1M | 37 | |
| 2014-12-31 | 28 | $762.6M | 29 | |
| 2014-09-30 | 27 | $722.9M | 27 | |
| 2014-06-30 | 30 | $823.9M | 65 | |
| 2014-03-31 | 30 | $875.6M | 63 | |
| 2013-12-31 | 25 | $726.4M | 41 | |
| 2013-09-30 | 26 | $701.2M | 55 | |
| 2013-06-30 | 25 | $579.8M | 0 |
Oracle Investment Management INC's most significant position changes for 2025-12-31: Sold out: Novavax, Inc. (NVAX); Sold out: Palantir Technologies Inc-a (PLTR); New buy: Novavax INC (NVAX 5 12-15-27); Sold out: Centene CORP (CNC); Sold out: Novavax INC (NVAX).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | WGS | Genedx Holdings CORP | +8.6% | -0.60% | Trim |
| 2 | ARDX | Ardelyx INC | +1.3% | +24.52% | Add |
| 3 | PSNL | Personalis INC | +0.7% | +47.90% | Add |
| 4 | TDOC | Teladoc Health, Inc. | +0.4% | +38.15% | Add |
| 5 | BIIB | Biogen INC | 0% | — | Unchanged |
| 6 | TSLA | Tesla INC | 0% | — | Unchanged |
| 7 | CAVA | Cava Group INC | -0.1% | — | Unchanged |
| 8 | ✓ | Ardelyx INC | -0.1% | -5.18% | Trim |
| 9 | SGMOQ | Sangamo Therapeutics INC | -0.2% | +3.09% | Add |
| 10 | QDEL | Quidelortho CORP | -0.2% | — | Unchanged |
| 11 | FORA | Forian INC | -0.2% | — | Unchanged |
| 12 | ✓ | Biohaven LTD | -1% | -15.31% | Trim |
| 13 | BHVN | Biohaven Ltd. | -1.8% | +4.35% | Add |
| 14 | TDOC | Teladoc Health INC | -1.9% | -49.77% | Trim |
| 15 | NVAX | Novavax, Inc. | — | EXIT | Sold out |
| 16 | PLTR | Palantir Technologies Inc-a | — | EXIT | Sold out |
| 17 | NVAX 5 12-15-27 | Novavax INC | — | NEW | New buy |
| 18 | CNC | Centene CORP | — | EXIT | Sold out |
| 19 | NVAX | Novavax INC | — | EXIT | Sold out |
| 20 | TSHA | Taysha Gene Therapies INC | — | NEW | New buy |
| 21 | EWTX | Edgewise Therapeutics INC | — | NEW | New buy |
| 22 | DAWNGBX | Day One Biopharmaceuticals I | — | NEW | New buy |
| 23 | KOID | Kraneshares Global Humanoid | — | EXIT | Sold out |
| 24 | PFE | Pfizer Inc. | — | NEW | New buy |
| 25 | ARKG | Ark Genomic Revolution ETF | — | NEW | New buy |
| 26 | TEM | Tempus Ai Inc-cl A | — | NEW | New buy |
| 27 | BDSX | Biodesix INC | — | EXIT | Sold out |
| 28 | HTZ | Hertz Global Hldgs INC | — | NEW | New buy |
| Period | Filed | Type | EDGAR |
|---|---|---|---|
| 2025-12-31 | 2026-02-18 | 13F-HR | View on EDGAR |
| 2025-09-30 | 2025-11-19 | 13F-HR | View on EDGAR |
| 2025-06-30 | 2025-08-15 | 13F-HR | View on EDGAR |
| 2025-03-31 | 2025-05-15 | 13F-HR | View on EDGAR |
| 2024-12-31 | 2025-02-14 | 13F-HR | View on EDGAR |
| 2024-09-30 | 2024-11-14 | 13F-HR | View on EDGAR |
| 2024-06-30 | 2024-08-14 | 13F-HR | View on EDGAR |
| 2024-03-31 | 2024-05-15 | 13F-HR | View on EDGAR |
| 2023-12-31 | 2024-02-14 | 13F-HR | View on EDGAR |
| 2023-09-30 | 2023-11-14 | 13F-HR | View on EDGAR |
| 2023-06-30 | 2023-08-14 | 13F-HR | View on EDGAR |
| 2023-03-31 | 2023-05-15 | 13F-HR | View on EDGAR |
| 2022-12-31 | 2023-02-14 | 13F-HR | View on EDGAR |
| 2022-09-30 | 2022-11-14 | 13F-HR | View on EDGAR |
| 2022-06-30 | 2022-08-15 | 13F-HR | View on EDGAR |
| 2022-03-31 | 2022-05-16 | 13F-HR | View on EDGAR |
| 2021-12-31 | 2022-02-14 | 13F-HR | View on EDGAR |
| 2021-09-30 | 2021-11-15 | 13F-HR | View on EDGAR |
| 2021-06-30 | 2021-08-16 | 13F-HR | View on EDGAR |
| 2021-03-31 | 2021-05-17 | 13F-HR | View on EDGAR |
| 2020-12-31 | 2021-02-16 | 13F-HR | View on EDGAR |
| 2020-09-30 | 2020-11-16 | 13F-HR | View on EDGAR |
| 2020-06-30 | 2020-08-14 | 13F-HR | View on EDGAR |
| 2020-03-31 | 2020-05-15 | 13F-HR | View on EDGAR |
| 2019-12-31 | 2020-02-14 | 13F-HR | View on EDGAR |
| 2019-09-30 | 2019-11-14 | 13F-HR | View on EDGAR |
| 2019-06-30 | 2019-08-14 | 13F-HR | View on EDGAR |
| 2019-03-31 | 2019-05-15 | 13F-HR | View on EDGAR |
| 2018-12-31 | 2019-02-14 | 13F-HR | View on EDGAR |
| 2018-09-30 | 2018-11-14 | 13F-HR | View on EDGAR |
| 2018-06-30 | 2018-08-14 | 13F-HR | View on EDGAR |
| 2018-03-31 | 2018-05-15 | 13F-HR | View on EDGAR |
| 2017-12-31 | 2018-02-14 | 13F-HR | View on EDGAR |
| 2017-09-30 | 2017-11-14 | 13F-HR | View on EDGAR |
| 2017-06-30 | 2017-08-14 | 13F-HR | View on EDGAR |
| 2017-03-31 | 2017-05-15 | 13F-HR | View on EDGAR |
| 2016-12-31 | 2017-02-14 | 13F-HR | View on EDGAR |
| 2016-09-30 | 2016-11-14 | 13F-HR | View on EDGAR |
| 2016-06-30 | 2016-08-15 | 13F-HR | View on EDGAR |
| 2016-03-31 | 2016-08-15 | Amendment | View on EDGAR |
| 2016-03-31 | 2016-05-16 | 13F-HR | View on EDGAR |
| 2015-12-31 | 2016-02-09 | 13F-HR | View on EDGAR |
| 2015-09-30 | 2015-11-16 | 13F-HR | View on EDGAR |
| 2015-09-30 | 2015-11-16 | Amendment | View on EDGAR |
| 2015-06-30 | 2015-08-14 | 13F-HR | View on EDGAR |
| 2015-03-31 | 2015-05-15 | 13F-HR | View on EDGAR |
| 2014-12-31 | 2015-02-17 | 13F-HR | View on EDGAR |
| 2014-09-30 | 2014-11-14 | 13F-HR | View on EDGAR |
| 2014-06-30 | 2014-08-14 | 13F-HR | View on EDGAR |
| 2014-03-31 | 2014-05-15 | 13F-HR | View on EDGAR |
| 2013-12-31 | 2014-02-14 | 13F-HR | View on EDGAR |
| 2013-09-30 | 2013-11-14 | 13F-HR | View on EDGAR |
| 2013-06-30 | 2013-08-14 | 13F-HR | View on EDGAR |
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