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CIK: 0001388325
Total reported value
$1.7B
$1.7B
24 檔
35.0%
The Q4 2025 SEC filing reveals that Novo Holdings A/S held a total portfolio value of $1.7B, covering 24 public equity positions.
In Q4 2025, Novo Holdings A/S adopted a defensive or profit-taking posture, trimming 3 positions and completely liquidating 4 holdings to manage risk exposure.
In terms of portfolio concentration, the top 5 core holdings (including BN, EWTX, ASML) accounted for 35.0% of total reported equity market value during Q4 2025.
Top New Position Initiated
MPLT
市值: $64.8M
Top Position Liquidated / Trimmed
VTI
前期市值: $340.8M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | BN | Brookfield CORP | Stock-Financials | 12.46% | -2.78% | +50.00% | |
| 2 | EWTX | Edgewise Therapeutics Inc | Stock-Other | 10.31% | -1.03% | — | |
| 3 | ASML | ASML Holding N.V. | Stock-Tech | 9.47% | +0.81% | -21.87% | |
| 4 | MIRM | Mirum Pharmaceuticals Inc | Stock-Other | 7.75% | -2.27% | — | |
| 5 | CRM | Salesforce Inc | Stock-Tech | 6.79% | -2.37% | — | |
| 6 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 5.87% | -1.69% | — | |
| 7 | VRDN | Viridian Therapeutics Inc | Stock-Other | 5.75% | -0.89% | — | |
| 8 | MPLT | Maplight Therapeutics Inc | Stock-Other | 5.03% | +1.60% | — | |
| 9 | ZBIO | Zenas Biopharma Inc | Stock-Other | 4.09% | — | -27.50% | |
| 10 | PHVS | Pharvaris N.V. | Stock-Other | 3.77% | -1.20% | — | |
| 11 | APGE | Apogee Therapeutics Inc | Stock-Other | 3.34% | -3.07% | EXIT | |
| 12 | PCVX | Vaxcyte Inc | Stock-Other | 3.28% | -1.35% | — | |
| 13 | BMRN | Biomarin Pharmaceutical Inc | Stock-Healthcare | 3.05% | -3.02% | EXIT | |
| 14 | AVBP | Arrivent Biopharma Inc | Stock-Other | 3.03% | -0.60% | — | |
| 15 | BABA | Alibaba Group Holding-sp Adr | Stock-Consumer Disc | 2.93% | -1.19% | — | |
| 16 | INSM | Insmed Inc | Stock-Healthcare | 2.70% | +0.75% | NEW | |
| 17 | CLDX | Celldex Therapeutics Inc | Stock-Other | 2.53% | -0.87% | — | |
| 18 | FDMT | 4d Molecular Therapeutics In | Stock-Other | 2.13% | -0.24% | +82.54% | |
| 19 | BBOT | Bridgebio Oncology Therapeut | Stock-Other | 1.91% | -0.59% | — | |
| 20 | ELVN | Enliven Therapeutics Inc | Stock-Other | 1.77% | -1.12% | +3.77% | |
| 21 | VALN | Valneva Se - Adr | Stock-Other | 1.58% | -0.54% | EXIT | |
| 22 | LNZA | Lanzatech Global Inc | Stock-Other | 0.17% | -0.15% | — | |
| 23 | MQ | Marqeta Inc-a | Stock-Other | 0.16% | +0.27% | — | |
| 24 | IOBTQ | Io Biotech Inc | Stock-Other | 0.12% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | EWTX | Edgewise Therapeutics Inc | +4.7% | — | Unchanged |
| 2 | VRDN | Viridian Therapeutics Inc | +2.4% | — | Unchanged |
| 3 | BN | Brookfield CORP | +2.2% | +50.00% | Add |
| 4 | APGE | Apogee Therapeutics Inc | +2.1% | +14.00% | Add |
| 5 | MIRM | Mirum Pharmaceuticals Inc | +1.8% | — | Unchanged |
| 6 | CRM | Salesforce Inc | +1.8% | — | Unchanged |
| 7 | CRNX | Crinetics Pharmaceuticals In | +1.5% | — | Unchanged |
| 8 | ZBIO | Zenas Biopharma Inc | +1.2% | -27.50% | Trim |
| 9 | PCVX | Vaxcyte Inc | +1.2% | — | Unchanged |
| 10 | FDMT | 4d Molecular Therapeutics In | +1% | +82.54% | Add |
| 11 | PHVS | Pharvaris N.V. | +1% | — | Unchanged |
| 12 | INSM | Insmed Inc | +0.8% | — | Unchanged |
| 13 | BMRN | Biomarin Pharmaceutical Inc | +0.8% | — | Unchanged |
| 14 | AVBP | Arrivent Biopharma Inc | +0.7% | — | Unchanged |
| 15 | CLDX | Celldex Therapeutics Inc | +0.5% | — | Unchanged |
| 16 | BBOT | Bridgebio Oncology Therapeut | +0.5% | — | Unchanged |
| 17 | ASML | ASML Holding N.V. | +0.4% | -21.87% | Trim |
| 18 | IOBTQ | Io Biotech Inc | +0.1% | — | Unchanged |
| 19 | MQ | Marqeta Inc-a | 0% | — | Unchanged |
| 20 | BABA | Alibaba Group Holding-sp Adr | 0% | — | Unchanged |
| 21 | LNZA | Lanzatech Global Inc | -0.1% | — | Unchanged |
| 22 | ELVN | Enliven Therapeutics Inc | -0.1% | +3.77% | Add |
| 23 | VALN | Valneva Se - Adr | -0.3% | -1.71% | Trim |
| 24 | VTI | Vanguard Total Stock Mkt ETF | — | EXIT | Sold out |
| 25 | ✓ | Merus N V | — | EXIT | Sold out |
| 26 | MPLT | Maplight Therapeutics Inc | — | NEW | New buy |
| 27 | RXRX | Recursion Pharmaceuticals-a | — | EXIT | Sold out |
| 28 | DMRA | Damora Therapeutics Inc | — | EXIT | Sold out |
According to official SEC Form 13F filings, Novo Holdings A/S reported a total U.S. public equity portfolio value of $1.7B across 24 disclosed positions in Q4 2025.
During Q4 2025, Novo Holdings A/S's top holdings by market value included BN (12.5%)、EWTX (10.3%)、ASML (9.5%). The largest single position, BN, represented 12.5% of total portfolio value.
In Q4 2025, Novo Holdings A/S made 12 total portfolio adjustments, initiating 1 new buys, adding to 4 positions, trimming 3 holdings, and fully liquidating 4 stocks.
All holding records on this page are fetched directly from the U.S. Securities and Exchange Commission (SEC) EDGAR system (Form 13F-HR). AlphaSMO parses CUSIP identifiers and formats data into Schema.org-compliant datasets.
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