KC
Knoll Capital Management, LLC — 13F Portfolio Changes & Top Buys (Q2 2026)
Knoll Capital Management, LLCCIK: 0001325083
Sector-focusedContrarianQuality / disciplined sizing
Total reported value
$179.3M
Reporting period: 2026-06-30 · Number of holdings: 37
Knoll Capital Management, LLC disclosed 37 holdings in its latest 13F filing for the period ending 2026-06-30, with total reported value of $179.3M and a quarterly turnover rate of 44.0%.
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Personality snowflake
- Concentration
- 18.87
- Portfolio Stability
- 43.96
- Momentum
- 0
- Sector conviction
- 100
- Diversification
- 74
- Sizing Uniformity
- 91.25
Knoll Capital Management, LLC's disclosed holdings carry a Herfindahl concentration index of 0.047 — mathematically equivalent to about 21 equally-sized positions, well below its 37 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 0.88), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
No strong tilt toward either adding to existing winners or initiating outsized new positions was observed in the latest reported quarter.
Sector classification currently covers about 34% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Source and citation information
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Recent moves
View source Form 13F filing on SEC.govTrim BHVN
0.0% -$19.7M
Add OR
0.0% $7.1M
Add OCUL
+91.6% $6.2M
Add MGTX
0.0% $6.1M
Add BAH
0.0% $4.7M
New buy ABVX
Holdings Map
New buyAddUnchangedTrim
Top 10 holdings by weight
Full holdings list this quarter
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | MGTX | MeiraGTx Holdings plc | Stock-Other | 9.42% | +3.41% | — | |
| 2 | PHYS | Sprott Physical Gold Trust | Stock-Other | 6.51% | -1.10% | — | |
| 3 | ALDX | Aldeyra Therapeutics Inc | Stock-Other | 6.50% | +1.36% | — | |
| 4 | OCUL | Ocular Therapeutix Inc | Stock-Other | 6.30% | +3.48% | +91.61% | |
| 5 | RGLD | Royal Gold Inc | Stock-Materials | 5.87% | -1.58% | — | |
| 6 | ✓ | Entera Bio LTD | Stock-Other | 5.81% | +2.22% | — | |
| 7 | NUVB | Nuvation Bio Inc | Stock-Other | 5.06% | +1.49% | +6.67% | |
| 8 | AEM | Agnico Eagle Mines LTD | Stock-Materials | 4.56% | -1.38% | — | |
| 9 | SEA1EUR | Seabridge Gold Inc | Stock-Other | 4.55% | -0.44% | — | |
| 10 | KGC | Kinross Gold CORP | Stock-Materials | 4.22% | -1.20% | — | |
| 11 | OR | Or Royalties Inc | Stock-Other | 3.97% | +3.97% | — | |
| 12 | SSRM | Ssr Mining Inc | Stock-Materials | 3.86% | -0.14% | — | |
| 13 | FNV | Franco-nevada CORP | Stock-Materials | 3.72% | -0.67% | — | |
| 14 | CGAU | Centerra Gold Inc | Stock-Other | 3.18% | -0.36% | — | |
| 15 | BAH | Booz Allen Hamilton Holdings | Stock-Industrials | 3.18% | +2.62% | — | |
| 16 | ELTX | Elicio Therapeutics Inc | Stock-Other | 2.64% | -1.10% | +92.10% | |
| 17 | ABVX | Abivax Sa-adr | Stock-Other | 2.60% | +2.60% | NEW | |
| 18 | PAAS | Pan American Silver CORP | Stock-Materials | 2.50% | -0.53% | — | |
| 19 | PSLV | Sprott Physical Silver Trust | Stock-Other | 2.34% | -0.67% | — | |
| 20 | TFPM | Triple Flag Precious Met | Stock-Materials | 1.92% | -0.30% | — | |
| 21 | ABEO | Abeona Therapeutics Inc | Stock-Other | 1.67% | +0.46% | — | |
| 22 | GROY | Gold Royalty CORP | Stock-Other | 1.54% | -0.45% | — | |
| 23 | NEWP | New Pacific Metals CORP | Stock-Other | 1.09% | -0.02% | — | |
| 24 | ITA | Ishares U.s. Aerospace & Def | ETF-Other | 1.03% | +0.10% | — | |
| 25 | PM | Philip Morris International | Stock-Consumer Staples | 1.01% | +0.09% | — | |
| 26 | CDE | Coeur Mining Inc | Stock-Materials | 0.87% | -0.12% | — | |
| 27 | AGI | Alamos Gold Inc-class A | Stock-Materials | 0.85% | -0.38% | — | |
| 28 | WPM | Wheaton Precious Metals CORP | Stock-Materials | 0.78% | -0.13% | — | |
| 29 | NOC | Northrop Grumman CORP | Stock-Industrials | 0.61% | -0.20% | — | |
| 30 | ELE | Elemental Royalty CORP | Stock-Other | 0.49% | -0.03% | — | |
| 31 | VMET | Versamet Royalties CORP | Stock-Other | 0.46% | +0.11% | — | |
| 32 | DC | Dakota Gold CORP | Stock-Other | 0.29% | -0.05% | — | |
| 33 | AMRZ | Amrize Ltd | Stock-Materials | 0.27% | -0.02% | — | |
| 34 | ALT | Altimmune Inc | Stock-Other | 0.27% | — | — | |
| 35 | PHAR | Pharming Group NV - Adr | Stock-Other | 0.03% | -0.01% | +0.84% | |
| 36 | ✓ | Orgenesis, Inc. | Stock-Other | 0.01% | -0.01% | — | |
| 37 | BHVN | Biohaven Ltd. | Stock-Other | — | -10.93% | — |
Portfolio Performance
Performance for Q3 2026
+11.1%
Performance Last 4 Quarters
+16.5%
- Stdev
- +36%
- Beta
- +1.24
- Alpha
- -7.8%
- Max Drawdown
- -30.9%
- Annualized Perf
- +10.9%
- Batting Avg vs S&P
- +52.8%
- Sortino
- +0.68
- Stutzer
- +0.14
- Treynor
- +0.14
- Sterling
- +0.28
- Calmar
- +0.35
- Information Ratio
- -0.09
- Tracking Error
- +32.4%
- Stdev Down
- +25%
- Winning Months %
- +58.3%
- Losing Months %
- +41.7%
- Best 12 Months
- +73%
- Worst 12 Months
- -11.8%
- Efficiency Ratio
- +0.13
- Sharpe
- +0.47
- Stdev Sectors
- +37.4%
- Skewness
- -0.75
- Kurtosis
- +1.07
- Upside Potential
- +2.23
Reported value over time
Sector allocation
Sector allocation over time
Quarterly history
| Period | Holdings | Total value | Stability | Top holdings | |
|---|---|---|---|---|---|
| 2026 Q2 | 37 | $179.3M | 44 | ||
| 2026 Q1 | 37 | $180.2M | 59 | ||
| 2025 Q4 | 34 | $218.0M | 35 | ||
| 2025 Q3 | 39 | $186.6M | 46 | ||
| 2025 Q2 | 38 | $140.7M | 0 | ||
| 2025 Q1 | 36 | $153.7M | 100 | ||
| 2024 Q4 | 35 | $155.3M | 0 | ||
| 2024 Q3 | 36 | $207.9M | 0 | ||
| 2024 Q2 | 35 | $148.4M | 0 | ||
| 2024 Q1 | 34 | $160.7M | 0 | ||
| 2023 Q4 | 32 | $120.8M | 0 | ||
| 2023 Q3 | 37 | $96.3M | 0 | ||
| 2023 Q2 | 27 | $82.5M | 0 | ||
| 2023 Q1 | 26 | $64.9M | 0 | ||
| 2022 Q4 | 21 | $44.3M | 0 | ||
| 2022 Q3 | 33 | $171.1M | 0 | ||
| 2022 Q2 | 41 | $175.2M | 0 | ||
| 2022 Q1 | 41 | $159.3M | 0 | ||
| 2021 Q4 | 38 | $182.0M | 0 | ||
| 2021 Q3 | 40 | $200.5M | 0 | ||
| 2021 Q2 | 42 | $191.5M | 28 | ||
| 2021 Q1 | 39 | $153.5M | 35 | ||
| 2020 Q4 | 31 | $146.7M | 26 | ||
| 2020 Q3 | 30 | $122.0M | 45 | ||
| 2020 Q2 | 19 | $173.2M | 50 | ||
| 2020 Q1 | 18 | $106.5M | 39 | ||
| 2019 Q4 | 18 | $135.4M | 39 | ||
| 2019 Q3 | 23 | $109.3M | 25 | ||
| 2019 Q2 | 22 | $122.2M | 29 | ||
| 2019 Q1 | 17 | $131.6M | 41 | ||
| 2018 Q4 | 15 | $87.9M | 33 | ||
| 2018 Q3 | 17 | $118.3M | 30 | ||
| 2018 Q2 | 19 | $117.7M | 34 | ||
| 2018 Q1 | 13 | $97.4M | 17 | ||
| 2017 Q4 | 12 | $113.4M | 25 | ||
| 2017 Q3 | 16 | $116.9M | 48 | ||
| 2017 Q2 | 15 | $75.4M | 54 | ||
| 2017 Q1 | 17 | $66.3M | 38 | ||
| 2016 Q4 | 17 | $57.0M | 55 | ||
| 2016 Q3 | 18 | $57.0M | 100 | ||
| 2016 Q2 | 22 | $308.5M | 29 | ||
| 2016 Q1 | 22 | $246.3M | 13 | ||
| 2015 Q4 | 21 | $269.7M | 19 | ||
| 2015 Q3 | 19 | $235.6M | 29 | ||
| 2015 Q2 | 19 | $310.2M | 26 | ||
| 2015 Q1 | 17 | $343.5M | 33 | ||
| 2014 Q4 | 14 | $254.1M | 100 | ||
| 2014 Q3 | 14 | $254.6M | 0 | ||
| 2014 Q2 | 15 | $224.4M | 20 | ||
| 2014 Q1 | 16 | $193.2M | 14 | ||
| 2013 Q4 | 14 | $198.6M | 15 | ||
| 2013 Q3 | 11 | $187.4M | 30 | ||
| 2013 Q2 | 11 | $146.2M | 0 |
* This report is exclusively curated by the AlphaSMO team. AlphaSMO is the web's most authoritative 13F / Inside Trader database, delivering precise insider trading and institutional holdings insights.
Holding changes this quarter
Knoll Capital Management, LLC's most significant position changes for 2026-06-30: New buy: Abivax Sa-adr (ABVX); Sold out: Cardiol Therapeutics Inc-a (CRDL); Add: Ocular Therapeutix Inc (OCUL) — shares +91.61%; Add: Nuvation Bio Inc (NUVB) — shares +6.67%; Add: Elicio Therapeutics Inc (ELTX) — shares +92.10%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | OR | Or Royalties Inc | +4% | — | Unchanged |
| 2 | OCUL | Ocular Therapeutix Inc | +3.5% | +91.61% | Add |
| 3 | MGTX | MeiraGTx Holdings plc | +3.4% | — | Unchanged |
| 4 | BAH | Booz Allen Hamilton Holdings | +2.6% | — | Unchanged |
| 5 | ABVX | Abivax Sa-adr | +2.6% | NEW | New buy |
| 6 | ✓ | Entera Bio LTD | +2.2% | — | Unchanged |
| 7 | NUVB | Nuvation Bio Inc | +1.5% | +6.67% | Add |
| 8 | ALDX | Aldeyra Therapeutics Inc | +1.4% | — | Unchanged |
| 9 | ABEO | Abeona Therapeutics Inc | +0.5% | — | Unchanged |
| 10 | VMET | Versamet Royalties CORP | +0.1% | — | Unchanged |
| 11 | ITA | Ishares U.s. Aerospace & Def | +0.1% | — | Unchanged |
| 12 | PM | Philip Morris International | +0.1% | — | Unchanged |
| 13 | ALT | Altimmune Inc | — | — | Unchanged |
| 14 | PHAR | Pharming Group NV - Adr | 0% | +0.84% | Add |
| 15 | ✓ | Orgenesis, Inc. | 0% | — | Unchanged |
| 16 | NEWP | New Pacific Metals CORP | 0% | — | Unchanged |
| 17 | AMRZ | Amrize Ltd | 0% | — | Unchanged |
| 18 | ELE | Elemental Royalty CORP | 0% | — | Unchanged |
| 19 | DC | Dakota Gold CORP | -0.1% | — | Unchanged |
| 20 | CRDL | Cardiol Therapeutics Inc-a | -0.1% | EXIT | Sold out |
| 21 | CDE | Coeur Mining Inc | -0.1% | — | Unchanged |
| 22 | WPM | Wheaton Precious Metals CORP | -0.1% | — | Unchanged |
| 23 | SSRM | Ssr Mining Inc | -0.1% | — | Unchanged |
| 24 | NOC | Northrop Grumman CORP | -0.2% | — | Unchanged |
| 25 | TFPM | Triple Flag Precious Met | -0.3% | — | Unchanged |
| 26 | CGAU | Centerra Gold Inc | -0.4% | — | Unchanged |
| 27 | AGI | Alamos Gold Inc-class A | -0.4% | — | Unchanged |
| 28 | SEA1EUR | Seabridge Gold Inc | -0.4% | — | Unchanged |
| 29 | GROY | Gold Royalty CORP | -0.5% | — | Unchanged |
| 30 | PAAS | Pan American Silver CORP | -0.5% | — | Unchanged |
| 31 | FNV | Franco-nevada CORP | -0.7% | — | Unchanged |
| 32 | PSLV | Sprott Physical Silver Trust | -0.7% | — | Unchanged |
| 33 | PHYS | Sprott Physical Gold Trust | -1.1% | — | Unchanged |
| 34 | ELTX | Elicio Therapeutics Inc | -1.1% | +92.10% | Add |
| 35 | KGC | Kinross Gold CORP | -1.2% | — | Unchanged |
| 36 | AEM | Agnico Eagle Mines LTD | -1.4% | — | Unchanged |
| 37 | RGLD | Royal Gold Inc | -1.6% | — | Unchanged |
| 38 | BHVN | Biohaven Ltd. | -10.9% | — | Unchanged |
Filing History
FAQ
What is Knoll Capital Management, LLC and what type of investor is it?
Knoll Capital Management, LLC is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-06-30), the firm manages a tracked equity portfolio valued at approximately $179.3M, spread across 37 disclosed positions.
What are Knoll Capital Management, LLC's largest equity positions?
Based on the latest 13F filing, Knoll Capital Management, LLC's top holdings by market value are:
1. MeiraGTx Holdings plc (MGTX) — $16.9M (9.4%)
2. Sprott Physical Gold Trust (PHYS) — $11.7M (6.5%)
3. Aldeyra Therapeutics Inc (ALDX) — $11.7M (6.5%)
4. Ocular Therapeutix Inc (OCUL) — $11.3M (6.3%)
5. Royal Gold Inc (RGLD) — $10.5M (5.9%)
What changes did Knoll Capital Management, LLC make in its most recent portfolio filing?
In the latest reported quarter, Knoll Capital Management, LLC made 6 notable position adjustments: 1 new positions were initiated, 4 existing holdings were added to, 0 positions were partially reduced, and 1 were completely exited. The largest of these moves: New buy: Abivax Sa-adr (ABVX); Sold out: Cardiol Therapeutics Inc-a (CRDL); Add: Ocular Therapeutix Inc (OCUL) — shares +91.61%; Add: Nuvation Bio Inc (NUVB) — shares +6.67%; Add: Elicio Therapeutics Inc (ELTX) — shares +92.10%
What sectors does Knoll Capital Management, LLC focus on?
Knoll Capital Management, LLC is concentrated in the following sectors based on its current disclosed equity portfolio:
• Materials: 86.0%
• Industrials: 11.1%
• Consumer Staples: 3.0%
Investment Profile
Knoll Capital Management, LLC returned an annualized 10.9% over the trailing 36 months — underperforming the S&P 500 by 7.8 points — based on a reconstructed track record of its disclosed 13F positions, with a beta of 1.24 (more volatile than the market) and a 53% quarterly batting average against the index.
Its portfolio is broadly diversified and moderately active, with 86.0% of the portfolio concentrated in Materials.
Its turnover score has risen from 0 to 44 over the past 4 quarters — a shift toward more active trading.
It has added to its MGTX position over the past two quarters (+$7.0M, now $16.9M), while trimming BHVN over the same stretch (-$26.3M, still holding $15.0).
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Developer Access
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REST API
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