CIK: 0000924223
Total reported value
$4.0B
Reporting period: 2019-03-31 · Number of holdings: 35
BB BIOTECH AG disclosed 35 holdings in its latest 13F filing for the period ending 2019-03-31, with total reported value of $4.0B and a quarterly turnover rate of 28.2%.
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Bb Biotech AG's disclosed holdings carry a Herfindahl concentration index of 0.060 — mathematically equivalent to about 17 equally-sized positions, well below its 35 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes are fairly uniform across the portfolio (a coefficient of variation of 1.07), suggesting a disciplined, rules-based approach to how much capital goes into each idea.
Recent activity leans toward adding more aggressively to already-large existing positions than to newly initiated ones (a 2.1 percentage-point tilt) — a pattern consistent with a momentum-following approach.
Sector classification currently covers about 8% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.
Trim ESPR
+3.8% -$14.6M
Add SG7
0.0% $87.0M
Trim VRTX
-5.1% $12.0M
Add BOLDEUR
+78.0% $37.0M
Add AGIO
+3.5% $68.1M
Trim GILD
-14.3% -$9.1M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | IONS | Ionis Pharmaceuticals INC | Stock-Healthcare | 15.76% | +0.62% | -11.63% | |
| 2 | INCY | Incyte CORP | Stock-Healthcare | 7.83% | +0.07% | -4.95% | |
| 3 | NBIX | Neurocrine Biosciences INC | Stock-Healthcare | 7.46% | -0.19% | +0.71% | |
| 4 | VRTX | Vertex Pharmaceuticals INC | Stock-Healthcare | 6.01% | -1.27% | -5.14% | |
| 5 | SG7 | Sage Therapeutics INC | Stock-Other | 5.50% | +1.28% | — | |
| 6 | CELG | Celgene CORP | Stock-Other | 5.22% | +0.49% | -4.51% | |
| 7 | AGIO | Agios Pharmaceuticals INC | Stock-Other | 5.05% | +0.80% | +3.47% | |
| 8 | ALXN | Alexion Pharmaceuticals INC | Stock-Other | 4.47% | +0.37% | — | |
| 9 | ALNY | Alnylam Pharmaceuticals INC | Stock-Healthcare | 3.83% | +0.16% | +3.80% | |
| 10 | ESPR | Esperion Therapeutics INC | Stock-Other | 3.56% | -1.44% | +3.83% | |
| 11 | RDUSEUR | Radius Health INC | Stock-Other | 3.40% | -0.14% | +1.06% | |
| 12 | HALO | Halozyme Therapeutics INC | Stock-Healthcare | 3.37% | -0.53% | — | |
| 13 | ARGX | Argenx Se - Adr | Stock-Healthcare | 2.84% | +0.12% | +2.26% | |
| 14 | MRNA | Moderna INC | Stock-Healthcare | 2.45% | +0.11% | — | |
| 15 | ✓ | Myovant Sciences LTD | Stock-Other | 2.16% | +0.27% | — | |
| 16 | ICPTUSD | Intercept Pharmaceuticals In | Stock-Other | 1.96% | +0.10% | +21.06% | |
| 17 | GILD | Gilead Sciences INC | Stock-Healthcare | 1.87% | -0.80% | -14.26% | |
| 18 | NKTREUR | Nektar Therapeutics | Stock-Other | 1.71% | +0.26% | +46.32% | |
| 19 | EXEL | Exelixis INC | Stock-Healthcare | 1.70% | -0.09% | — | |
| 20 | AKCAEUR | Akcea Therapeutics INC | Stock-Other | 1.69% | -0.61% | -0.37% | |
| 21 | MYOKEUR | Myokardia INC | Stock-Other | 1.65% | +0.28% | +44.19% | |
| 22 | MGNX | Macrogenics INC | Stock-Other | 1.54% | +0.20% | +3.56% | |
| 23 | WVE | Wave Life Sciences Ltd. | Stock-Other | 1.43% | -0.54% | — | |
| 24 | VYGR | Voyager Therapeutics INC | Stock-Other | 1.38% | +0.52% | — | |
| 25 | BOLDEUR | Audentes Therapeutics INC | Stock-Other | 1.34% | +0.81% | +78.01% | |
| 26 | ALDR1EUR | Alder Biopharmaceuticals INC | Stock-Other | 0.95% | +0.04% | — | |
| 27 | CRSP | CRISPR Therapeutics AG | Stock-Healthcare | 0.73% | +0.73% | NEW | |
| 28 | SRRK | Scholar Rock Holding CORP | Stock-Other | 0.70% | -0.24% | +15.38% | |
| 29 | ITCIEUR | Intra-cellular Therapies INC | Stock-Other | 0.67% | -0.13% | — | |
| 30 | SGMOQ | Sangamo Therapeutics INC | Stock-Other | 0.64% | +0.14% | +96.30% | |
| 31 | ✓ | Stock-Other | 0.54% | -0.08% | +49.13% | ||
| 32 | GTHXEUR | G1 Therapeutics INC | Stock-Other | 0.28% | -0.13% | — | |
| 33 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.15% | -0.02% | — | |
| 34 | NVAX | Novavax, Inc. | Stock-Healthcare | 0.12% | -0.37% | — | |
| 35 | FIXXEUR | Homology Medicines INC | Stock-Other | 0.06% | +0.06% | NEW |
Not enough priced holdings yet to compute performance
| Period | Holdings | Total value | Stability | Top holdings |
|---|---|---|---|---|
| 2019-03-31 | 35 | $4.0B | 28 | |
| 2018-12-31 | 34 | $3.1B | 32 | |
| 2018-09-30 | 32 | $3.8B | 17 | |
| 2018-06-30 | 32 | $3.5B | 17 | |
| 2018-03-31 | 30 | $3.6B | 17 | |
| 2017-12-31 | 30 | $3.6B | 21 | |
| 2017-09-30 | 27 | $3.6B | 16 | |
| 2017-06-30 | 28 | $3.3B | 13 | |
| 2017-03-31 | 30 | $3.1B | 16 | |
| 2016-12-31 | 29 | $2.7B | 21 | |
| 2016-09-30 | 29 | $2.8B | 26 | |
| 2016-06-30 | 30 | $2.5B | 17 | |
| 2016-03-31 | 29 | $2.5B | 34 | |
| 2015-12-31 | 30 | $3.5B | 34 | |
| 2015-09-30 | 28 | $3.2B | 25 | |
| 2015-06-30 | 29 | $3.7B | 24 | |
| 2015-03-31 | 27 | $3.4B | 18 | |
| 2014-12-31 | 28 | $3.1B | 27 | |
| 2014-09-30 | 26 | $2.5B | 22 | |
| 2014-06-30 | 24 | $2.1B | 21 | |
| 2014-03-31 | 24 | $1.9B | 12 | |
| 2013-12-31 | 23 | $1.9B | 19 | |
| 2013-09-30 | 24 | $1.8B | 34 | |
| 2013-06-30 | 23 | $1.4B | 0 |
Bb Biotech AG's most significant position changes for 2019-03-31: New buy: CRISPR Therapeutics AG (CRSP); Sold out: Regeneron Pharmaceuticals (REGN); New buy: Homology Medicines INC (FIXXEUR); Add: Esperion Therapeutics INC (ESPR) — shares +3.83%; Trim: Vertex Pharmaceuticals INC (VRTX) — shares -5.14%.
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | SG7 | Sage Therapeutics INC | +1.3% | — | Unchanged |
| 2 | BOLDEUR | Audentes Therapeutics INC | +0.8% | +78.01% | Add |
| 3 | AGIO | Agios Pharmaceuticals INC | +0.8% | +3.47% | Add |
| 4 | IONS | Ionis Pharmaceuticals INC | +0.6% | -11.63% | Trim |
| 5 | VYGR | Voyager Therapeutics INC | +0.5% | — | Unchanged |
| 6 | CELG | Celgene CORP | +0.5% | -4.51% | Trim |
| 7 | ALXN | Alexion Pharmaceuticals INC | +0.4% | — | Unchanged |
| 8 | MYOKEUR | Myokardia INC | +0.3% | +44.19% | Add |
| 9 | ✓ | Myovant Sciences LTD | +0.3% | — | Unchanged |
| 10 | NKTREUR | Nektar Therapeutics | +0.3% | +46.32% | Add |
| 11 | MGNX | Macrogenics INC | +0.2% | +3.56% | Add |
| 12 | ALNY | Alnylam Pharmaceuticals INC | +0.2% | +3.80% | Add |
| 13 | SGMOQ | Sangamo Therapeutics INC | +0.1% | +96.30% | Add |
| 14 | ARGX | Argenx Se - Adr | +0.1% | +2.26% | Add |
| 15 | MRNA | Moderna INC | +0.1% | — | Unchanged |
| 16 | ICPTUSD | Intercept Pharmaceuticals In | +0.1% | +21.06% | Add |
| 17 | INCY | Incyte CORP | +0.1% | -4.95% | Trim |
| 18 | ALDR1EUR | Alder Biopharmaceuticals INC | 0% | — | Unchanged |
| 19 | ✓ | Cidara Therapeutics INC Com New | 0% | — | Unchanged |
| 20 | ✓ | -0.1% | +49.13% | Add | |
| 21 | EXEL | Exelixis INC | -0.1% | — | Unchanged |
| 22 | ITCIEUR | Intra-cellular Therapies INC | -0.1% | — | Unchanged |
| 23 | GTHXEUR | G1 Therapeutics INC | -0.1% | — | Unchanged |
| 24 | RDUSEUR | Radius Health INC | -0.1% | +1.06% | Add |
| 25 | NBIX | Neurocrine Biosciences INC | -0.2% | +0.71% | Add |
| 26 | SRRK | Scholar Rock Holding CORP | -0.2% | +15.38% | Add |
| 27 | NVAX | Novavax, Inc. | -0.4% | — | Unchanged |
| 28 | HALO | Halozyme Therapeutics INC | -0.5% | — | Unchanged |
| 29 | WVE | Wave Life Sciences Ltd. | -0.5% | — | Unchanged |
| 30 | AKCAEUR | Akcea Therapeutics INC | -0.6% | -0.37% | Trim |
| 31 | GILD | Gilead Sciences INC | -0.8% | -14.26% | Trim |
| 32 | VRTX | Vertex Pharmaceuticals INC | -1.3% | -5.14% | Trim |
| 33 | ESPR | Esperion Therapeutics INC | -1.4% | +3.83% | Add |
| 34 | CRSP | CRISPR Therapeutics AG | — | NEW | New buy |
| 35 | REGN | Regeneron Pharmaceuticals | — | EXIT | Sold out |
| 36 | FIXXEUR | Homology Medicines INC | — | NEW | New buy |
| Period | Filed | Type | EDGAR |
|---|---|---|---|
| 2019-03-31 | 2019-05-13 | 13F-HR | View on EDGAR |
| 2018-12-31 | 2019-02-12 | 13F-HR | View on EDGAR |
| 2018-09-30 | 2018-11-09 | 13F-HR | View on EDGAR |
| 2018-06-30 | 2018-08-09 | 13F-HR | View on EDGAR |
| 2018-03-31 | 2018-05-08 | 13F-HR | View on EDGAR |
| 2017-12-31 | 2018-02-14 | 13F-HR | View on EDGAR |
| 2017-09-30 | 2017-11-13 | 13F-HR | View on EDGAR |
| 2017-06-30 | 2017-08-11 | 13F-HR | View on EDGAR |
| 2017-03-31 | 2017-05-10 | 13F-HR | View on EDGAR |
| 2016-12-31 | 2017-02-14 | 13F-HR | View on EDGAR |
| 2016-09-30 | 2016-11-10 | 13F-HR | View on EDGAR |
| 2016-06-30 | 2016-08-12 | 13F-HR | View on EDGAR |
| 2016-03-31 | 2016-05-12 | 13F-HR | View on EDGAR |
| 2015-12-31 | 2016-02-09 | 13F-HR | View on EDGAR |
| 2015-09-30 | 2015-11-12 | 13F-HR | View on EDGAR |
| 2015-06-30 | 2015-08-12 | 13F-HR | View on EDGAR |
| 2015-03-31 | 2015-05-14 | 13F-HR | View on EDGAR |
| 2014-12-31 | 2015-02-12 | 13F-HR | View on EDGAR |
| 2014-09-30 | 2014-11-13 | 13F-HR | View on EDGAR |
| 2014-06-30 | 2014-08-07 | 13F-HR | View on EDGAR |
| 2014-03-31 | 2014-05-08 | 13F-HR | View on EDGAR |
| 2013-12-31 | 2014-02-12 | 13F-HR | View on EDGAR |
| 2013-09-30 | 2013-11-12 | 13F-HR | View on EDGAR |
| 2013-06-30 | 2013-08-14 | 13F-HR | View on EDGAR |
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