Allostery Investments LP 13F Filing History & Holdings

CIK: 0001978599

High-turnover trader

Total reported value

—

Reporting period: 2025-09-30 · Number of holdings: 1

Allostery Investments LP disclosed 1 holdings in its latest 13F filing for the period ending 2025-09-30, with total reported value of — and a quarterly turnover rate of 100.0%.

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Personality snowflake

Concentration: 0
Portfolio Stability: 100
Momentum/Contrarian: 50
Sector conviction: 0
Diversification: 2
Sizing Uniformity: —

Sector classification currently covers about 0% of this portfolio's disclosed value; the remainder includes holdings (e.g. unmapped tickers, options, or other security types) not yet covered by our sector mapping.

Recent moves

Sold out ABVX
Sold out 260
Sold out 4XC1
Sold out N5749R100
Sold out EOLS
Sold out APGE

Holdings Map

Top 10 holdings by weight

Full holdings list this quarter

#	Ticker	Issuer	Asset Subclass	Weight	Weight Change	Shares Change	4Q Trend
1	✓	Ikena Oncology INC	Stock-Other	—	—	—

Portfolio Performance

Performance for Q3 2026

—

Performance Last 4 Quarters

+53.6%

Based on 53% of reported portfolio value with available pricing

Stdev: +38.8%
Beta: +0.48
Alpha: +66.2%
Max Drawdown: -6%
Annualized Perf: +90.6%
Batting Avg vs S&P: +66.7%
Sortino: +5.81
Stutzer: +0.6
Treynor: +1.5
Sterling: —
Calmar: +14.99
Information Ratio: +1.54
Tracking Error: +38.9%
Stdev Down: +12.4%
Winning Months %: +66.7%
Losing Months %: +33.3%
Best 12 Months: —
Worst 12 Months: —
Efficiency Ratio: +0.62
Sharpe: +1.86
Stdev Sectors: —
Skewness: 0
Kurtosis: -1.62
Upside Potential: +7.81

Reported value over time

Sector allocation

Not enough sector-mapped data yet

Sector allocation over time

Quarterly history

Period	Holdings	Total value	Stability	Top holdings
2025-09-30	1	—	100
2025-06-30	20	$7.9M	0	1ABVX 2AKRO 3AMLX Top holdings2025-06-30 1.ABVX 2.AKRO 3.AMLX 4.260 5.EOLS 6.RZLT 7.N5749R 8.4XC1 9.FULC 10.APGE
2025-03-31	41	$69.3M	0	1ABVX 2260 34XC1 Top holdings2025-03-31 1.ABVX 2.260 3.4XC1 4.N5749R 5.EOLS 6.APGE 7.ALKS 8.008064 9.G9TY5A 10.ACLXGBX
2024-12-31	40	$95.7M	0	1XBI 2QQQ 3TLT Top holdings2024-12-31 1.XBI 2.QQQ 3.TLT 4.260 5.EOLS 6.APGE 7.ABVX 8.4XC1 9.G9TY5A 10.ALKS

Holding changes this quarter

Allostery Investments LP's most significant position changes for 2025-09-30: Sold out: Abivax Sa-adr (ABVX); Sold out: Centessa Pharmaceuticals-adr (260); Sold out: Kalvista Pharmaceuticals INC (4XC1); Sold out: Merus N V; Sold out: Evolus INC (EOLS).

Position changes disclosed by Allostery Investments LP for the quarter ending 2025-09-30, including ticker, issuer, weight change, shares change, and action
#	Ticker	Issuer	Weight Change	Shares Change	Action
1	ABVX	Abivax Sa-adr	—	EXIT	Sold out
2	260	Centessa Pharmaceuticals-adr	—	EXIT	Sold out
3	4XC1	Kalvista Pharmaceuticals INC	—	EXIT	Sold out
4	✓	Merus N V	—	EXIT	Sold out
5	EOLS	Evolus INC	—	EXIT	Sold out
6	APGE	Apogee Therapeutics INC	—	EXIT	Sold out
7	ALKS	Alkermes plc	—	EXIT	Sold out
8	✓		—	EXIT	Sold out
9	✓	Zura Bio LTD	—	EXIT	Sold out
10	ACLXGBX	Arcellx INC	—	EXIT	Sold out
11	CYTK	Cytokinetics INC	—	EXIT	Sold out
12	BBIO	Bridgebio Pharma INC	—	EXIT	Sold out
13	SWTXUSD	Springworks Therapeutics INC	—	EXIT	Sold out
14	BEAM	Beam Therapeutics INC	—	EXIT	Sold out
15	SLNOEUR	Soleno Therapeutics INC	—	EXIT	Sold out
16	PCVX	Vaxcyte INC	—	EXIT	Sold out
17	IONS	Ionis Pharmaceuticals INC	—	EXIT	Sold out
18	XENE	Xenon Pharmaceuticals INC	—	EXIT	Sold out
19	AMLX	Amylyx Pharmaceuticals INC	—	EXIT	Sold out
20	AVTX	Avalo Therapeutics INC	—	EXIT	Sold out
21	VRNA	Verona Pharma PLC - Adr	—	EXIT	Sold out
22	INSM	Insmed INC	—	EXIT	Sold out
23	AKRO	Akero Therapeutics INC	—	EXIT	Sold out
24	TARS	Tarsus Pharmaceuticals INC	—	EXIT	Sold out
25	GOSS	Gossamer Bio INC	—	EXIT	Sold out
26	PLRX	Pliant Therapeutics INC	—	EXIT	Sold out
27	CNTX	Context Therapeutics INC	—	EXIT	Sold out
28	✓		—	EXIT	Sold out
29	✓	Rallybio CORP	—	EXIT	Sold out
30	ELDN	Eledon Pharmaceuticals INC	—	EXIT	Sold out
31	CLYM	Climb Bio INC	—	EXIT	Sold out
32	ORKA	Oruka Therapeutics INC	—	EXIT	Sold out
33	MDGL	Madrigal Pharmaceuticals INC	—	EXIT	Sold out
34	ETNBGBP	89bio INC	—	EXIT	Sold out
35	PMNEUR	Promis Neurosciences INC	—	EXIT	Sold out
36	LEGN	Legend Biotech Corp-adr	—	EXIT	Sold out
37	VIR	Vir Biotechnology INC	—	EXIT	Sold out
38	WVE	Wave Life Sciences Ltd.	—	EXIT	Sold out
39	ARQT	Arcutis Biotherapeutics INC	—	EXIT	Sold out
40	EWTX	Edgewise Therapeutics INC	—	EXIT	Sold out
41	LXEO	Lexeo Therapeutics INC	—	EXIT	Sold out
42	✓	Ikena Oncology INC	—	—	Unchanged

Filing History

Period	Filed	Type	EDGAR
2025-09-30	2025-11-14	13F-HR	View on EDGAR
2025-06-30	2025-08-14	13F-HR	View on EDGAR
2025-03-31	2025-05-15	13F-HR	View on EDGAR
2024-12-31	2025-02-14	13F-HR	View on EDGAR

FAQ

What is Allostery Investments LP and what type of investor is it?

Allostery Investments LP is an investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2025-09-30), the firm manages a tracked equity portfolio valued at approximately —, spread across 1 disclosed positions.

What are Allostery Investments LP's largest equity positions?

Based on the latest 13F filing, Allostery Investments LP's top holdings by market value are: 1. Ikena Oncology INC — $0.0

What changes did Allostery Investments LP make in its most recent portfolio filing?

In the latest quarter, Allostery Investments LP took a more defensive posture — trimming 0 positions and completely exiting 41 holdings. The largest of these moves: Sold out: Abivax Sa-adr (ABVX); Sold out: Centessa Pharmaceuticals-adr (260); Sold out: Kalvista Pharmaceuticals INC (4XC1); Sold out: Merus N V; Sold out: Evolus INC (EOLS)

What sectors does Allostery Investments LP focus on?

Sector breakdown data is not yet available for Allostery Investments LP. Check back after the next 13F processing cycle.

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Total reported value

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Concentration0.0

Portfolio Stability0.0

Sector conviction0.0

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Kresge Foundation

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Total reported value

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Concentration0.0

Portfolio Stability0.0

Sector conviction0.0

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Resource America, INC.

CIK 0000083402

Total reported value

—

1 stks

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Concentration0.0

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Personality snowflake

Concentration

Portfolio Stability

100

Momentum/Contrarian

Sector conviction

Diversification

Sizing Uniformity

—

Ticker

Issuer

Asset Subclass

Weight

Weight Change

Shares Change

4Q Trend

✓

Ikena Oncology INC

Stock-Other

—

Portfolio Performance

Performance for Q3 2026

—

Performance Last 4 Quarters

+53.6%

Based on 53% of reported portfolio value with available pricing

Stdev: +38.8%
Beta: +0.48
Alpha: +66.2%
Max Drawdown: -6%
Annualized Perf: +90.6%
Batting Avg vs S&P: +66.7%
Sortino: +5.81
Stutzer: +0.6
Treynor: +1.5
Sterling: —
Calmar: +14.99
Information Ratio: +1.54
Tracking Error: +38.9%
Stdev Down: +12.4%
Winning Months %: +66.7%
Losing Months %: +33.3%
Best 12 Months: —
Worst 12 Months: —
Efficiency Ratio: +0.62
Sharpe: +1.86
Stdev Sectors: —
Skewness: 0
Kurtosis: -1.62
Upside Potential: +7.81

Quarterly history

Period	Holdings	Total value	Stability	Top holdings
2025-09-30	1	—	100
2025-06-30	20	$7.9M	0	1ABVX 2AKRO 3AMLX Top holdings2025-06-30 1.ABVX 2.AKRO 3.AMLX 4.260 5.EOLS 6.RZLT 7.N5749R 8.4XC1 9.FULC 10.APGE
2025-03-31	41	$69.3M	0	1ABVX 2260 34XC1 Top holdings2025-03-31 1.ABVX 2.260 3.4XC1 4.N5749R 5.EOLS 6.APGE 7.ALKS 8.008064 9.G9TY5A 10.ACLXGBX
2024-12-31	40	$95.7M	0	1XBI 2QQQ 3TLT Top holdings2024-12-31 1.XBI 2.QQQ 3.TLT 4.260 5.EOLS 6.APGE 7.ABVX 8.4XC1 9.G9TY5A 10.ALKS