CIK: 0000810386
Total reported value
$415.8M
Reporting period: 2026-03-31 · Number of holdings: 31
Howard Hughes Medical Institute disclosed 31 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $415.8M and a quarterly turnover rate of 157.5%.
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Howard Hughes Medical Institute's disclosed holdings carry a Herfindahl concentration index of 0.085 — mathematically equivalent to about 12 equally-sized positions, well below its 31 actual disclosed holdings. That gap points to a strategy built around a small core of high-conviction bets rather than broad diversification.
Position sizes vary widely across the portfolio (a coefficient of variation of 1.29), with a handful of outsized bets alongside many smaller positions.
Recent activity leans toward initiating meaningfully larger new positions than it adds to existing ones (a 2.5 percentage-point tilt) — a pattern consistent with a more contrarian, new-idea-driven approach.
Trim SPY
-62.9% -$104.9M
Add NVDA
+6069.4% $55.2M
Add AAPL
+6142.3% $49.6M
Add GOOGL
+11393.2% $40.9M
Add MSFT
+6294.6% $37.1M
Add AMZN
+6248.4% $27.2M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SPY | Ss Spdr S&p 500 ETF Trust-us | ETF-Large Cap & Growth | 13.79% | -79.06% | -62.93% | |
| 2 | NVDA | Nvidia CORP | Stock-Tech | 13.51% | +12.95% | +6069.41% | |
| 3 | AAPL | Apple INC | Stock-Tech | 12.13% | +11.63% | +6142.31% | |
| 4 | GOOGL | Alphabet Inc-cl A | Stock-Comm Services | 9.94% | +9.72% | +11393.20% | |
| 5 | MSFT | Microsoft CORP | Stock-Tech | 9.11% | +8.67% | +6294.63% | |
| 6 | AMZN | Amazon.com INC | Stock-Consumer Disc | 6.66% | +6.38% | +6248.35% | |
| 7 | TSM | Taiwan Semiconductor-sp Adr | Stock-Tech | 5.43% | +5.43% | NEW | |
| 8 | AVGO | Broadcom INC | Stock-Tech | 4.84% | +4.64% | +6300.39% | |
| 9 | META | Meta Platforms Inc-class A | Stock-Comm Services | 4.24% | +4.06% | +6464.39% | |
| 10 | TSLA | Tesla INC | Stock-Consumer Disc | 3.68% | +3.52% | +6728.69% | |
| 11 | ASML | ASML Holding N.V. | Stock-Tech | 1.72% | +1.72% | NEW | |
| 12 | NFLX | Netflix INC | Stock-Comm Services | 1.36% | +1.31% | +6326.07% | |
| 13 | MU | Micron Technology INC | Stock-Tech | 1.28% | +1.24% | +6416.18% | |
| 14 | AMD | Advanced Micro Devices | Stock-Tech | 1.11% | +1.07% | +6364.00% | |
| 15 | PLTR | Palantir Technologies Inc-a | Stock-Tech | 1.08% | +1.03% | +6176.94% | |
| 16 | CSCO | Cisco Systems INC | Stock-Tech | 0.94% | +0.90% | +5820.71% | |
| 17 | AMAT | Applied Materials INC | Stock-Tech | 0.90% | +0.87% | +6286.05% | |
| 18 | LRCX | Lam Research CORP | Stock-Tech | 0.89% | +0.86% | +6342.96% | |
| 19 | ORCL | Oracle CORP | Stock-Tech | 0.84% | +0.80% | +6525.28% | |
| 20 | IBM | Intl Business Machines CORP | Stock-Tech | 0.76% | +0.73% | +6379.10% | |
| 21 | KLAC | Kla CORP | Stock-Tech | 0.65% | +0.63% | +6417.86% | |
| 22 | SAP | Sap Se-sponsored Adr | Stock-Tech | 0.61% | +0.61% | NEW | |
| 23 | INTC | Intel CORP | Stock-Tech | 0.61% | +0.59% | +5821.45% | |
| 24 | TXN | Texas Instruments INC | Stock-Tech | 0.59% | +0.57% | +6351.53% | |
| 25 | DIS | Walt Disney Co/the | Stock-Comm Services | 0.57% | +0.54% | +6305.19% | |
| 26 | CRM | Salesforce INC | Stock-Tech | 0.57% | +0.54% | +6052.20% | |
| 27 | UBER | Uber Technologies INC | Stock-Industrials | 0.50% | +0.48% | +6364.21% | |
| 28 | QCOM | Qualcomm INC | Stock-Tech | 0.46% | +0.44% | +6295.69% | |
| 29 | BKNG | Booking Holdings INC | Stock-Consumer Disc | 0.45% | +0.43% | +6242.86% | |
| 30 | ACN | Accenture plc | Stock-Tech | 0.41% | +0.39% | +6323.13% | |
| 31 | INTU | Intuit INC | Stock-Tech | 0.39% | +0.37% | +6223.33% |
Performance for Q3 2026
0%
Performance Last 4 Quarters
+14.8%
Based on 82% of reported portfolio value with available pricing
| Period | Holdings | Total value | Stability | Top holdings |
|---|---|---|---|---|
| 2026-03-31 | 31 | $415.8M | 100 | |
| 2025-12-31 | 500 | $174.7M | 3 | |
| 2025-09-30 | 500 | $170.6M | 27 | |
| 2025-06-30 | 501 | $250.9M | 0 | |
| 2025-03-31 | 2 | $202.2M | 100 | |
| 2024-12-31 | 2 | $568.4M | 0 | |
| 2024-09-30 | 2 | $630.4M | 0 | |
| 2024-06-30 | 1 | $466.2M | 0 | |
| 2024-03-31 | 2 | $332.9M | 0 | |
| 2023-12-31 | 2 | $301.3M | 0 | |
| 2023-09-30 | 2 | $19.6M | 0 | |
| 2023-06-30 | 2 | $70.4M | 0 | |
| 2023-03-31 | 5 | $56.4M | 0 | |
| 2022-12-31 | 19 | $179.6M | 0 | |
| 2022-09-30 | 40 | $351.7M | 0 | |
| 2022-06-30 | 19 | $185.1M | 0 | |
| 2022-03-31 | 20 | $228.1M | 0 | |
| 2021-12-31 | 22 | $255.1M | 0 | |
| 2021-09-30 | 23 | $296.6M | 0 | |
| 2021-06-30 | 23 | $299.0M | 99 | |
| 2021-03-31 | 23 | $293.7M | 70 | |
| 2020-12-31 | 22 | $427.3M | 39 | |
| 2020-09-30 | 21 | $304.3M | 63 | |
| 2020-06-30 | 22 | $245.0M | 90 | |
| 2020-03-31 | 22 | $476.9M | 90 | |
| 2019-12-31 | 25 | $279.2M | 37 | |
| 2019-09-30 | 25 | $357.2M | 67 | |
| 2019-06-30 | 25 | $209.1M | 75 | |
| 2019-03-31 | 27 | $428.9M | 54 | |
| 2018-12-31 | 30 | $315.6M | 15 | |
| 2018-09-30 | 27 | $342.4M | 20 | |
| 2018-06-30 | 27 | $395.7M | 31 | |
| 2018-03-31 | 27 | $384.5M | 5 | |
| 2017-12-31 | 28 | $385.4M | 35 | |
| 2017-09-30 | 31 | $402.8M | 65 | |
| 2017-06-30 | 155 | $548.6M | 53 | |
| 2017-03-31 | 149 | $543.6M | 40 | |
| 2016-12-31 | 147 | $437.8M | 44 | |
| 2016-09-30 | 151 | $388.2M | 46 | |
| 2016-06-30 | 161 | $297.7M | 68 | |
| 2016-03-31 | 158 | $453.7M | 68 | |
| 2015-12-31 | 166 | $656.8M | 37 | |
| 2015-09-30 | 158 | $534.7M | 44 | |
| 2015-06-30 | 161 | $472.0M | 61 | |
| 2015-03-31 | 162 | $736.9M | 86 | |
| 2014-12-31 | 164 | $373.9M | 64 | |
| 2014-09-30 | 179 | $449.4M | 46 | |
| 2014-06-30 | 178 | $595.4M | 33 | |
| 2014-03-31 | 196 | $704.5M | 60 | |
| 2013-12-31 | 192 | $663.2M | 36 | |
| 2013-09-30 | 200 | $652.6M | 93 | |
| 2013-06-30 | 208 | $303.8M | 0 |
Howard Hughes Medical Institute's most significant position changes for 2026-03-31: New buy: Taiwan Semiconductor-sp Adr (TSM); New buy: ASML Holding N.V. (ASML); New buy: Sap Se-sponsored Adr (SAP); Sold out: Alphabet Inc-cl C (GOOG); Sold out: Berkshire Hathaway Inc-cl B (BRK-B).
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | NVDA | Nvidia CORP | +13% | +6069.41% | Add |
| 2 | AAPL | Apple INC | +11.6% | +6142.31% | Add |
| 3 | GOOGL | Alphabet Inc-cl A | +9.7% | +11393.20% | Add |
| 4 | MSFT | Microsoft CORP | +8.7% | +6294.63% | Add |
| 5 | AMZN | Amazon.com INC | +6.4% | +6248.35% | Add |
| 6 | AVGO | Broadcom INC | +4.6% | +6300.39% | Add |
| 7 | META | Meta Platforms Inc-class A | +4.1% | +6464.39% | Add |
| 8 | TSLA | Tesla INC | +3.5% | +6728.69% | Add |
| 9 | NFLX | Netflix INC | +1.3% | +6326.07% | Add |
| 10 | MU | Micron Technology INC | +1.2% | +6416.18% | Add |
| 11 | AMD | Advanced Micro Devices | +1.1% | +6364.00% | Add |
| 12 | PLTR | Palantir Technologies Inc-a | +1% | +6176.94% | Add |
| 13 | CSCO | Cisco Systems INC | +0.9% | +5820.71% | Add |
| 14 | AMAT | Applied Materials INC | +0.9% | +6286.05% | Add |
| 15 | LRCX | Lam Research CORP | +0.9% | +6342.96% | Add |
| 16 | ORCL | Oracle CORP | +0.8% | +6525.28% | Add |
| 17 | IBM | Intl Business Machines CORP | +0.7% | +6379.10% | Add |
| 18 | KLAC | Kla CORP | +0.6% | +6417.86% | Add |
| 19 | INTC | Intel CORP | +0.6% | +5821.45% | Add |
| 20 | TXN | Texas Instruments INC | +0.6% | +6351.53% | Add |
| 21 | DIS | Walt Disney Co/the | +0.5% | +6305.19% | Add |
| 22 | CRM | Salesforce INC | +0.5% | +6052.20% | Add |
| 23 | UBER | Uber Technologies INC | +0.5% | +6364.21% | Add |
| 24 | QCOM | Qualcomm INC | +0.4% | +6295.69% | Add |
| 25 | BKNG | Booking Holdings INC | +0.4% | +6242.86% | Add |
| 26 | ACN | Accenture plc | +0.4% | +6323.13% | Add |
| 27 | INTU | Intuit INC | +0.4% | +6223.33% | Add |
| 28 | SPY | Ss Spdr S&p 500 ETF Trust-us | -79.1% | -62.93% | Trim |
| 29 | TSM | Taiwan Semiconductor-sp Adr | — | NEW | New buy |
| 30 | ASML | ASML Holding N.V. | — | NEW | New buy |
| 31 | SAP | Sap Se-sponsored Adr | — | NEW | New buy |
| 32 | GOOG | Alphabet Inc-cl C | — | EXIT | Sold out |
| 33 | BRK-B | Berkshire Hathaway Inc-cl B | — | EXIT | Sold out |
| 34 | JPM | Jpmorgan Chase & Co | — | EXIT | Sold out |
| 35 | LLY | Eli Lilly & Co | — | EXIT | Sold out |
| 36 | V | Visa Inc-class A Shares | — | EXIT | Sold out |
| 37 | XOM | Exxon Mobil CORP | — | EXIT | Sold out |
| 38 | JNJ | Johnson & Johnson | — | EXIT | Sold out |
| 39 | WMT | Walmart INC | — | EXIT | Sold out |
| 40 | MA | Mastercard INC - A | — | EXIT | Sold out |
| 41 | ABBV | Abbvie INC | — | EXIT | Sold out |
| 42 | COST | Costco Wholesale CORP | — | EXIT | Sold out |
| 43 | BAC | Bank Of America CORP | — | EXIT | Sold out |
| 44 | HD | Home Depot INC | — | EXIT | Sold out |
| 45 | PG | Procter & Gamble Co/the | — | EXIT | Sold out |
| 46 | GE | General Electric | — | EXIT | Sold out |
| 47 | UNH | Unitedhealth Group INC | — | EXIT | Sold out |
| 48 | WFC | Wells Fargo & Co | — | EXIT | Sold out |
| 49 | CVX | Chevron CORP | — | EXIT | Sold out |
| 50 | KO | Coca-cola Co/the | — | EXIT | Sold out |
| Period | Filed | Type | EDGAR |
|---|---|---|---|
| 2026-03-31 | 2026-05-15 | 13F-HR | View on EDGAR |
| 2025-12-31 | 2026-02-17 | 13F-HR | View on EDGAR |
| 2025-09-30 | 2025-11-14 | 13F-HR | View on EDGAR |
| 2025-06-30 | 2025-08-14 | 13F-HR | View on EDGAR |
| 2025-03-31 | 2025-05-15 | 13F-HR | View on EDGAR |
| 2024-12-31 | 2025-02-14 | 13F-HR | View on EDGAR |
| 2024-09-30 | 2024-11-14 | 13F-HR | View on EDGAR |
| 2024-06-30 | 2024-08-14 | 13F-HR | View on EDGAR |
| 2024-03-31 | 2024-05-15 | 13F-HR | View on EDGAR |
| 2023-12-31 | 2024-02-14 | 13F-HR | View on EDGAR |
| 2023-09-30 | 2023-11-14 | 13F-HR | View on EDGAR |
| 2023-06-30 | 2023-08-14 | 13F-HR | View on EDGAR |
| 2023-03-31 | 2023-05-15 | 13F-HR | View on EDGAR |
| 2022-12-31 | 2023-02-14 | 13F-HR | View on EDGAR |
| 2022-09-30 | 2022-11-14 | 13F-HR | View on EDGAR |
| 2022-06-30 | 2022-08-12 | 13F-HR | View on EDGAR |
| 2022-03-31 | 2022-05-12 | 13F-HR | View on EDGAR |
| 2021-12-31 | 2022-02-10 | 13F-HR | View on EDGAR |
| 2021-09-30 | 2021-11-10 | 13F-HR | View on EDGAR |
| 2021-06-30 | 2021-08-10 | 13F-HR | View on EDGAR |
| 2021-03-31 | 2021-05-06 | 13F-HR | View on EDGAR |
| 2020-12-31 | 2021-02-12 | 13F-HR | View on EDGAR |
| 2020-09-30 | 2020-11-10 | 13F-HR | View on EDGAR |
| 2020-06-30 | 2020-08-13 | 13F-HR | View on EDGAR |
| 2020-03-31 | 2020-05-08 | 13F-HR | View on EDGAR |
| 2019-12-31 | 2020-02-12 | 13F-HR | View on EDGAR |
| 2019-09-30 | 2019-11-08 | 13F-HR | View on EDGAR |
| 2019-06-30 | 2019-08-09 | 13F-HR | View on EDGAR |
| 2019-03-31 | 2019-05-14 | 13F-HR | View on EDGAR |
| 2018-12-31 | 2019-02-13 | 13F-HR | View on EDGAR |
| 2018-09-30 | 2018-11-09 | 13F-HR | View on EDGAR |
| 2018-06-30 | 2018-07-31 | 13F-HR | View on EDGAR |
| 2018-03-31 | 2018-05-02 | 13F-HR | View on EDGAR |
| 2017-12-31 | 2018-02-06 | 13F-HR | View on EDGAR |
| 2017-09-30 | 2017-11-02 | 13F-HR | View on EDGAR |
| 2017-06-30 | 2017-08-11 | 13F-HR | View on EDGAR |
| 2017-03-31 | 2017-04-25 | 13F-HR | View on EDGAR |
| 2016-12-31 | 2017-02-01 | 13F-HR | View on EDGAR |
| 2016-09-30 | 2016-11-10 | 13F-HR | View on EDGAR |
| 2016-06-30 | 2016-08-03 | 13F-HR | View on EDGAR |
| 2016-03-31 | 2016-05-10 | 13F-HR | View on EDGAR |
| 2015-12-31 | 2016-02-11 | 13F-HR | View on EDGAR |
| 2015-09-30 | 2015-11-16 | 13F-HR | View on EDGAR |
| 2015-06-30 | 2015-08-13 | 13F-HR | View on EDGAR |
| 2015-03-31 | 2015-05-14 | 13F-HR | View on EDGAR |
| 2014-12-31 | 2015-02-11 | 13F-HR | View on EDGAR |
| 2014-09-30 | 2014-11-04 | 13F-HR | View on EDGAR |
| 2014-06-30 | 2014-08-01 | 13F-HR | View on EDGAR |
| 2014-03-31 | 2014-05-08 | 13F-HR | View on EDGAR |
| 2013-12-31 | 2014-02-10 | 13F-HR | View on EDGAR |
| 2013-09-30 | 2013-11-08 | 13F-HR | View on EDGAR |
| 2013-06-30 | 2013-08-08 | 13F-HR | View on EDGAR |
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