CIK: 0001224962
Total reported value
$5.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | AM6 | Amicus Therapeutics INC | Stock-Other | 9.48% | -1.62% | EXIT | |
| 2 | MDGL | Madrigal Pharmaceuticals INC | Stock-Healthcare | 8.41% | — | +211.74% | |
| 3 | AMLX | Amylyx Pharmaceuticals INC | Stock-Other | 6.32% | — | +11.26% | |
| 4 | CERE1EUR | Cerevel Therapeutics Holding | Stock-Other | 5.77% | — | — | |
| 5 | ✓ | Stock-Other | 3.75% | — | -17.42% | ||
| 6 | VRNA | Verona Pharma PLC - Adr | Stock-Other | 3.58% | — | -3.30% | |
| 7 | ✓ | Horizon Therapeutics PLC | Stock-Other | 3.07% | — | — | |
| 8 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 2.79% | — | -21.31% | |
| 9 | LIANY | Lianbio-adr | Stock-Other | 2.65% | — | — | |
| 10 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 2.36% | — | +156.62% | |
| 11 | INBXUSD | Inhibrx INC | Stock-Other | 2.29% | — | +14.75% | |
| 12 | ACLXGBX | Arcellx INC | Stock-Other | 2.26% | -1.70% | EXIT | |
| 13 | ALDX | Aldeyra Therapeutics INC | Stock-Other | 2.22% | -0.39% | EXIT | |
| 14 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 2.13% | — | -9.48% | |
| 15 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 2.08% | — | -24.09% | |
| 16 | BLU | Bellus Health INC | Stock-Other | 2.05% | — | -13.23% | |
| 17 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 1.91% | — | -24.57% | |
| 18 | NUVL | Nuvalent Inc-a | Stock-Other | 1.89% | — | +36.25% | |
| 19 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 1.79% | — | -2.70% | |
| 20 | PCVX | Vaxcyte INC | Stock-Other | 1.58% | — | — | |
| 21 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 1.47% | — | +50.52% | |
| 22 | ADMA | Adma Biologics INC | Stock-Healthcare | 1.30% | — | +8.84% | |
| 23 | MGTX | MeiraGTx Holdings plc | Stock-Other | 1.27% | — | — | |
| 24 | TMCI | Treace Medical Concepts INC | Stock-Other | 1.26% | — | +21.50% | |
| 25 | VERUEUR | Veru INC | Stock-Other | 1.17% | — | +101.85% | |
| 26 | BDQM | Albireo Pharma INC | Stock-Other | 1.07% | — | -25.55% | |
| 27 | COGT | Cogent Biosciences INC | Stock-Other | 1.04% | — | — | |
| 28 | VRDN | Viridian Therapeutics INC | Stock-Other | 1.00% | -1.24% | — | |
| 29 | ✓ | Rapt Therapeutics INC | Stock-Other | 1.00% | — | +5.01% | |
| 30 | ZYME | Zymeworks INC | Stock-Other | 1.00% | — | — | |
| 31 | ACRV | Acrivon Therapeutics INC | Stock-Other | 0.97% | — | — | |
| 32 | ✓ | Establishment Labs Hldgs INC | Stock-Other | 0.92% | — | -13.90% | |
| 33 | CATBUSD | Astria Therapeutics INC | Stock-Other | 0.92% | -1.51% | EXIT | |
| 34 | ✓ | Cincor Pharma INC | Stock-Other | 0.89% | — | -22.09% | |
| 35 | ✓ | Immatics NV | Stock-Other | 0.85% | — | +39.66% | |
| 36 | RLAY | Relay Therapeutics INC | Stock-Other | 0.82% | +1.61% | — | |
| 37 | LYRAGBP | Lyra Therapeutics INC | Stock-Other | 0.81% | — | — | |
| 38 | OMGBP | Outset Medical INC | Stock-Other | 0.79% | — | -6.78% | |
| 39 | HRMY | Harmony Biosciences Holdings | Stock-Other | 0.64% | — | — | |
| 40 | RCKT | Rocket Pharmaceuticals INC | Stock-Other | 0.59% | — | +115.64% | |
| 41 | VAC2USD | Vbi Vaccines INC | Stock-Other | 0.57% | — | — | |
| 42 | ✓ | Rain Oncology INC Com | Stock-Other | 0.56% | — | — | |
| 43 | AKRO | Akero Therapeutics INC | Stock-Other | 0.54% | — | -18.48% | |
| 44 | TARS | Tarsus Pharmaceuticals INC | Stock-Other | 0.53% | — | — | |
| 45 | SLDB | Solid Biosciences INC | Stock-Other | 0.53% | +0.49% | — | |
| 46 | NAUT | Nautilus Biotechnology INC | Stock-Other | 0.46% | +0.51% | — | |
| 47 | ROIV | Roivant Sciences Ltd. | Stock-Healthcare | 0.44% | +1.39% | — | |
| 48 | ✓ | Athira Pharma INC | Stock-Other | 0.43% | — | — | |
| 49 | PRTA | Prothena Corporation plc | Stock-Other | 0.40% | — | +3.32% | |
| 50 | ✓ | Verrica Pharmaceuticals INC | Stock-Other | 0.39% | — | — |