SC
Stonepine Capital Management, LLC
高频交易型行业集中型逆势操作型
申报总市值
US$2.5亿
申报季度: 2026-03-31 · 持股只数: 83
Stonepine Capital Management, LLC在最新一期 13F 报告中披露了 83 项持股，申报期为 2026-03-31，总持股市值约为 US$2.5亿，季度换手率为 105.9%。
机构性格雪花图
- 集中度
- 74.44
- 持仓稳定性
- 100
- 动能／逆势
- 0
- 行业集中度
- 100
- 多样化
- 100
- 仓位均衡度
- 64.54
近期动向
减仓 VSTM
+20.9% -US$358.9万
加仓 TENX
+8106.0% US$1544.9万
减仓 EOLS
+33.6% -US$189.4万
减仓 ADMA
+155.4% US$353.1万
减仓 IKT
-59.2% -US$320.6万
减仓 ABEO
-6.9% -US$100.0万
持仓地图
新建仓加仓不变减仓
前十大持股占比
本季完整持股清单
仅显示前 72 大持股（共 83 只）
| # | 代码 | 标的名称 | 资产子类别 | 占比 | 占比变动 | 持仓量变化 | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | XBI | Ss Spdr S&p Biotech ETF | ETF-科技型 | 40.92% | +40.92% | NEW | |
| 2 | VSTM | Verastem INC | 股票-其他 | 7.01% | -8.39% | +20.87% | |
| 3 | ADMA | Adma Biologics INC | 股票-医疗保健 | 6.82% | -3.03% | +155.41% | |
| 4 | TENX | Tenax Therapeutics INC | 股票-其他 | 6.24% | +6.13% | +8105.99% | |
| 5 | EOLS | Evolus INC | 股票-其他 | 3.59% | -4.33% | +33.56% | |
| 6 | CAMP | Camp4 Therapeutics CORP | 股票-其他 | 2.45% | +1.43% | +507.10% | |
| 7 | NKTR | Nektar Therapeutics | 股票-其他 | 2.45% | — | -37.04% | |
| 8 | 430 | Terns Pharmaceuticals INC | 股票-其他 | 2.11% | +2.11% | NEW | |
| 9 | ZVRA | Zevra Therapeutics INC | 股票-其他 | 1.79% | -1.93% | -15.65% | |
| 10 | ABEO | Abeona Therapeutics INC | 股票-其他 | 1.52% | -1.98% | -6.92% | |
| 11 | CRBP | Corbus Pharmaceuticals Holdi | 股票-其他 | 1.44% | — | -1.66% | |
| 12 | ✓ | Establishment Labs Hldgs INC | 股票-其他 | 1.27% | +1.27% | NEW | |
| 13 | KZIA | Kazia Therapeutics-spon Adr | 股票-其他 | 1.03% | -1.29% | -25.02% | |
| 14 | ANTX | An2 Therapeutics INC | 股票-其他 | 0.98% | +0.46% | +13.73% | |
| 15 | ARE | Alexandria Real Estate Equit | 股票-房地产 | 0.93% | — | — | |
| 16 | ACAD | Acadia Pharmaceuticals INC | 股票-医疗保健 | 0.89% | — | — | |
| 17 | ✓ | 股票-其他 | 0.88% | +0.88% | NEW | ||
| 18 | XOMA | Xoma Royalty Corporation | 股票-其他 | 0.87% | -1.36% | -39.57% | |
| 19 | AYTU | Aytu Biopharma INC | 股票-其他 | 0.87% | — | -2.63% | |
| 20 | CRIS | Curis INC | 股票-其他 | 0.82% | +0.78% | +6178.80% | |
| 21 | HRTX | Heron Therapeutics INC | 股票-其他 | 0.77% | — | +94.07% | |
| 22 | CTMX | Cytomx Therapeutics INC | 股票-其他 | 0.75% | +0.75% | NEW | |
| 23 | XERS | Xeris Biopharma Holdings INC | 股票-其他 | 0.74% | +0.74% | NEW | |
| 24 | TELA | Tela Bio INC | 股票-其他 | 0.65% | -1.38% | +11.28% | |
| 25 | IKT | Inhibikase Therapeutics INC | 股票-其他 | 0.64% | -2.87% | -59.24% | |
| 26 | ✓ | Crescent Biopharma INC. | 股票-其他 | 0.63% | — | -3.06% | |
| 27 | ACET | Adicet Bio INC | 股票-其他 | 0.61% | — | +0.88% | |
| 28 | SIBN | Si-bone INC | 股票-其他 | 0.58% | +0.58% | NEW | |
| 29 | XFOR | X4 Pharmaceuticals INC | 股票-其他 | 0.55% | -1.18% | -43.51% | |
| 30 | ✓ | Okyo Pharma LTD | 股票-其他 | 0.55% | +0.55% | NEW | |
| 31 | MNKD | Mannkind CORP | 股票-其他 | 0.51% | +0.15% | +497.85% | |
| 32 | NMRA | Neumora Therapeutics INC | 股票-其他 | 0.47% | +0.47% | NEW | |
| 33 | LUNG | Pulmonx CORP | 股票-其他 | 0.40% | — | +57.95% | |
| 34 | INAB | In8bio INC | 股票-其他 | 0.39% | +0.11% | +302.33% | |
| 35 | SRZN | Surrozen INC | 股票-其他 | 0.39% | -1.49% | -70.95% | |
| 36 | DCTH | Delcath Systems INC | 股票-其他 | 0.37% | +0.17% | +267.21% | |
| 37 | ARDX | Ardelyx INC | 股票-其他 | 0.36% | +0.36% | NEW | |
| 38 | PMVP | Pmv Pharmaceuticals INC | 股票-其他 | 0.35% | -0.70% | -38.47% | |
| 39 | BIOA | Bioage Labs INC | 股票-其他 | 0.35% | — | +11.11% | |
| 40 | ✓ | Connect Biopharma Hldgs LTD | 股票-其他 | 0.33% | +0.33% | NEW | |
| 41 | RADX | Radiopharm Theranostics LTD | 股票-其他 | 0.30% | — | — | |
| 42 | MXCT | Maxcyte INC | 股票-其他 | 0.28% | — | +114.21% | |
| 43 | CDXS | Codexis INC | 股票-其他 | 0.27% | — | +63.21% | |
| 44 | BOLD | Boundless Bio INC | 股票-其他 | 0.26% | — | -15.83% | |
| 45 | HELP | Cybin INC | 股票-其他 | 0.26% | -1.77% | -60.56% | |
| 46 | ZNTL | Zentalis Pharmaceuticals INC | 股票-其他 | 0.25% | — | -41.97% | |
| 47 | KTTA | Pasithea Therapeutics CORP | 股票-其他 | 0.25% | — | +202.22% | |
| 48 | MSLE | Satellos Bioscience INC | 股票-其他 | 0.23% | +0.23% | NEW | |
| 49 | PHAT | Phathom Pharmaceuticals INC | 股票-其他 | 0.22% | +0.22% | NEW | |
| 50 | OKUR | Onkure Therapeutics Inc-a | 股票-其他 | 0.22% | +0.22% | NEW |
1–50 of 72
申报总市值趋势
行业配置
历年行业分布趋势
季度历史总览
| 季度 | 持股只数 | 总市值 | 稳定性 | 主要持股 |
|---|---|---|---|---|
| 2026-03-31 | 83 | US$2.5亿 | 100 | |
| 2025-12-31 | 66 | US$1.4亿 | 62 | |
| 2025-09-30 | 58 | US$1.2亿 | 100 | |
| 2025-06-30 | 59 | US$1.0亿 | 0 | |
| 2025-03-31 | 66 | US$1.0亿 | 100 | |
| 2024-12-31 | 52 | US$1.2亿 | 0 | |
| 2024-09-30 | 38 | US$1.6亿 | 0 | |
| 2024-06-30 | 25 | US$1.1亿 | 0 | |
| 2024-03-31 | 20 | US$1.3亿 | 0 | |
| 2023-12-31 | 16 | US$2.3亿 | 0 | |
| 2023-09-30 | 23 | US$3.0亿 | 0 | |
| 2023-06-30 | 19 | US$2.7亿 | 0 | |
| 2023-03-31 | 22 | US$3.0亿 | 0 | |
| 2022-12-31 | 19 | US$2.4亿 | 0 | |
| 2022-09-30 | 19 | US$2.2亿 | 0 | |
| 2022-06-30 | 25 | US$2.1亿 | 0 | |
| 2022-03-31 | 28 | US$2.4亿 | 0 | |
| 2021-12-31 | 23 | US$2.2亿 | 0 | |
| 2021-09-30 | 31 | US$2.2亿 | 0 | |
| 2021-06-30 | 26 | US$1.9亿 | 98 | |
| 2021-03-31 | 29 | US$1.9亿 | 100 | |
| 2020-12-31 | 21 | US$1.3亿 | 60 | |
| 2020-09-30 | 17 | US$9613.1万 | 70 | |
| 2020-06-30 | 13 | US$5163.0万 | 85 | |
| 2020-03-31 | 27 | US$9455.7万 | 100 | |
| 2019-12-31 | 23 | US$1.4亿 | 79 | |
| 2019-09-30 | 26 | US$1.0亿 | 63 | |
| 2019-06-30 | 25 | US$1.5亿 | 37 | |
| 2019-03-31 | 30 | US$1.7亿 | 82 | |
| 2018-12-31 | 22 | US$1.1亿 | 68 | |
| 2018-09-30 | 31 | US$1.7亿 | 53 | |
| 2018-06-30 | 25 | US$1.6亿 | 54 | |
| 2018-03-31 | 30 | US$1.9亿 | 73 | |
| 2017-12-31 | 27 | US$1.7亿 | 67 | |
| 2017-09-30 | 22 | US$1.7亿 | 57 | |
| 2017-06-30 | 27 | US$1.9亿 | 66 | |
| 2017-03-31 | 21 | US$1.8亿 | 38 | |
| 2016-12-31 | 23 | US$1.7亿 | 100 | |
| 2016-09-30 | 17 | US$1.2亿 | 100 | |
| 2016-06-30 | 23 | US$9753.7万 | 84 | |
| 2016-03-31 | 19 | US$8479.4万 | 64 | |
| 2015-12-31 | 13 | US$8536.1万 | 0 |
本季持股变动
Stonepine Capital Management, LLC 在 2026-03-31 最显著的持仓异动： 新建仓: Ss Spdr S&p Biotech ETF (XBI); 新建仓: Terns Pharmaceuticals INC (430); 清仓: Indivior Pharmaceuticals, Inc. (INDV); 新建仓: Establishment Labs Hldgs INC; 清仓: CRISPR Therapeutics AG (CRSP).
| # | 代码 | 标的名称 | 占比变动 | 持仓量变化 | 异动类型 |
|---|---|---|---|---|---|
| 1 | TENX | Tenax Therapeutics INC | +6.1% | +8105.99% | 加仓 |
| 2 | CAMP | Camp4 Therapeutics CORP | +1.4% | +507.10% | 加仓 |
| 3 | CRIS | Curis INC | +0.8% | +6178.80% | 加仓 |
| 4 | ANTX | An2 Therapeutics INC | +0.5% | +13.73% | 加仓 |
| 5 | DCTH | Delcath Systems INC | +0.2% | +267.21% | 加仓 |
| 6 | MNKD | Mannkind CORP | +0.2% | +497.85% | 加仓 |
| 7 | INAB | In8bio INC | +0.1% | +302.33% | 加仓 |
| 8 | EDSA | Edesa Biotech INC | -0.7% | -95.64% | 减仓 |
| 9 | QNRX | Quoin Pharmaceuticals Lt-adr | -0.7% | -31.63% | 减仓 |
| 10 | PMVP | Pmv Pharmaceuticals INC | -0.7% | -38.47% | 减仓 |
| 11 | OABI | Omniab INC | -0.9% | -76.60% | 减仓 |
| 12 | ELDN | Eledon Pharmaceuticals INC | -0.9% | -96.08% | 减仓 |
| 13 | XFOR | X4 Pharmaceuticals INC | -1.2% | -43.51% | 减仓 |
| 14 | KZIA | Kazia Therapeutics-spon Adr | -1.3% | -25.02% | 减仓 |
| 15 | XOMA | Xoma Royalty Corporation | -1.4% | -39.57% | 减仓 |
| 16 | TELA | Tela Bio INC | -1.4% | +11.28% | 加仓 |
| 17 | SRZN | Surrozen INC | -1.5% | -70.95% | 减仓 |
| 18 | HELP | Cybin INC | -1.8% | -60.56% | 减仓 |
| 19 | ZVRA | Zevra Therapeutics INC | -1.9% | -15.65% | 减仓 |
| 20 | VRCA | Verrica Pharmaceuticals INC | -1.9% | -71.80% | 减仓 |
| 21 | ABEO | Abeona Therapeutics INC | -2% | -6.92% | 减仓 |
| 22 | IKT | Inhibikase Therapeutics INC | -2.9% | -59.24% | 减仓 |
| 23 | ADMA | Adma Biologics INC | -3% | +155.41% | 加仓 |
| 24 | EOLS | Evolus INC | -4.3% | +33.56% | 加仓 |
| 25 | VSTM | Verastem INC | -8.4% | +20.87% | 加仓 |
| 26 | XBI | Ss Spdr S&p Biotech ETF | — | NEW | 新建仓 |
| 27 | 430 | Terns Pharmaceuticals INC | — | NEW | 新建仓 |
| 28 | INDV | Indivior Pharmaceuticals, Inc. | — | EXIT | 清仓 |
| 29 | ✓ | Establishment Labs Hldgs INC | — | NEW | 新建仓 |
| 30 | CRSP | CRISPR Therapeutics AG | — | EXIT | 清仓 |
| 31 | RARE | Ultragenyx Pharmaceutical In | — | EXIT | 清仓 |
| 32 | ✓ | — | NEW | 新建仓 | |
| 33 | CTMX | Cytomx Therapeutics INC | — | NEW | 新建仓 |
| 34 | DAWNGBX | Day One Biopharmaceuticals I | — | EXIT | 清仓 |
| 35 | XERS | Xeris Biopharma Holdings INC | — | NEW | 新建仓 |
| 36 | SPRB | Spruce Biosciences INC | — | EXIT | 清仓 |
| 37 | ENTA | Enanta Pharmaceuticals INC | — | EXIT | 清仓 |
| 38 | SIBN | Si-bone INC | — | NEW | 新建仓 |
| 39 | ✓ | Okyo Pharma LTD | — | NEW | 新建仓 |
| 40 | MIST | Milestone Pharmaceuticals In | — | EXIT | 清仓 |
| 41 | NMRA | Neumora Therapeutics INC | — | NEW | 新建仓 |
| 42 | GERN | Geron CORP | — | EXIT | 清仓 |
| 43 | 2KZ0 | Kezar Life Sciences INC | — | EXIT | 清仓 |
| 44 | ARDX | Ardelyx INC | — | NEW | 新建仓 |
| 45 | ✓ | Connect Biopharma Hldgs LTD | — | NEW | 新建仓 |
| 46 | SMLR | Semler Scientific INC | — | EXIT | 清仓 |
| 47 | GOSS | Gossamer Bio INC | — | EXIT | 清仓 |
| 48 | MSLE | Satellos Bioscience INC | — | NEW | 新建仓 |
| 49 | PHAT | Phathom Pharmaceuticals INC | — | NEW | 新建仓 |
| 50 | OKUR | Onkure Therapeutics Inc-a | — | NEW | 新建仓 |
FAQ
Stonepine Capital Management, LLC 是什么机构？属于哪种投资人类型？
Stonepine Capital Management, LLC 是一家投资管理机构，每季依规定向 SEC 申报 Form 13F，披露其在美国上市股票的持仓信息。根据最新一期申报（2026-03-31），该机构追踪的股票投资组合估值约为 US$2.5亿，分布在 83 个已申报仓位之中。
Stonepine Capital Management, LLC 目前前几大持股有哪些？
根据最新 13F 申报，Stonepine Capital Management, LLC 按市值排列的前几大持股为：
1. Ss Spdr S&p Biotech ETF (XBI) — US$1.0亿 (40.9%)
2. Verastem INC (VSTM) — US$1750.2万 (7.0%)
3. Adma Biologics INC (ADMA) — US$1702.9万 (6.8%)
4. Tenax Therapeutics INC (TENX) — US$1559.3万 (6.2%)
5. Evolus INC (EOLS) — US$895.6万 (3.6%)
Stonepine Capital Management, LLC 在最新一期 13F 申报中做了哪些操作？
在最新申报季度中，Stonepine Capital Management, LLC 共进行了 50 项显著调整：新建仓 14 个仓位、加仓 11 个既有持股、减仓 14 个仓位，并完全清仓 11 个持股。 其中幅度最大的异动：新建仓: Ss Spdr S&p Biotech ETF (XBI); 新建仓: Terns Pharmaceuticals INC (430); 清仓: Indivior Pharmaceuticals, Inc. (INDV); 新建仓: Establishment Labs Hldgs INC; 清仓: CRISPR Therapeutics AG (CRSP)
Stonepine Capital Management, LLC 主要集中投资哪些行业板块？
根据目前已申报的股票投资组合，Stonepine Capital Management, LLC 的主要板块分布如下：
• Health Care: 89.2%
• Real Estate: 10.8%
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