CIK: 0001224962
Total reported value
$5.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | CERE1EUR | Cerevel Therapeutics Holding | Stock-Other | 10.38% | — | +8.69% | |
| 2 | AM6 | Amicus Therapeutics INC | Stock-Other | 8.89% | -1.62% | EXIT | |
| 3 | LIANY | Lianbio-adr | Stock-Other | 5.74% | — | — | |
| 4 | ACLXGBX | Arcellx INC | Stock-Other | 5.63% | -1.70% | EXIT | |
| 5 | NUVL | Nuvalent Inc-a | Stock-Other | 4.79% | — | +18.45% | |
| 6 | INBXUSD | Inhibrx INC | Stock-Other | 3.61% | — | — | |
| 7 | SLNOEUR | Soleno Therapeutics INC | Stock-Other | 2.76% | — | — | |
| 8 | RYTM | Rhythm Pharmaceuticals INC | Stock-Other | 2.21% | -0.83% | +465.64% | |
| 9 | IMVT | Immunovant INC | Stock-Other | 2.19% | — | -38.97% | |
| 10 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 2.17% | — | +0.14% | |
| 11 | CBAYUSD | Cymabay Therapeutics INC | Stock-Other | 2.12% | — | -0.46% | |
| 12 | AXSM | Axsome Therapeutics INC | Stock-Healthcare | 1.84% | — | +115.51% | |
| 13 | MDT | Medtronic plc | Stock-Healthcare | 1.80% | — | +66.38% | |
| 14 | CRGX | Cargo Therapeutics INC | Stock-Other | 1.78% | — | — | |
| 15 | MGTX | MeiraGTx Holdings plc | Stock-Other | 1.78% | — | — | |
| 16 | VRNA | Verona Pharma PLC - Adr | Stock-Other | 1.72% | — | -3.52% | |
| 17 | BHVN | Biohaven Ltd. | Stock-Other | 1.65% | — | +129.45% | |
| 18 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 1.59% | — | +28.73% | |
| 19 | BBIO | Bridgebio Pharma INC | Stock-Healthcare | 1.58% | — | — | |
| 20 | PCVX | Vaxcyte INC | Stock-Other | 1.53% | — | -18.94% | |
| 21 | LYRAGBP | Lyra Therapeutics INC | Stock-Other | 1.49% | — | — | |
| 22 | IRON | Disc Medicine INC | Stock-Other | 1.32% | -0.64% | EXIT | |
| 23 | SYRE | Spyre Therapeutics INC | Stock-Other | 1.25% | +1.94% | +3113.52% | |
| 24 | NTRA | Natera INC | Stock-Healthcare | 1.19% | — | +289.69% | |
| 25 | ✓ | Rapt Therapeutics INC | Stock-Other | 1.19% | — | +11.42% | |
| 26 | ✓ | Verrica Pharmaceuticals INC | Stock-Other | 1.16% | — | +40.89% | |
| 27 | RCKT | Rocket Pharmaceuticals INC | Stock-Other | 1.14% | — | +12.52% | |
| 28 | APGE | Apogee Therapeutics INC | Stock-Other | 1.14% | -0.61% | — | |
| 29 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 1.13% | — | +78.26% | |
| 30 | ✓ | Rayzebio INC | Stock-Other | 1.03% | — | -4.22% | |
| 31 | CABA | Cabaletta Bio INC | Stock-Other | 1.01% | — | +76.87% | |
| 32 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 1.00% | — | -0.65% | |
| 33 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 0.97% | — | +59.83% | |
| 34 | EOLS | Evolus INC | Stock-Other | 0.93% | — | +166.75% | |
| 35 | VRDN | Viridian Therapeutics INC | Stock-Other | 0.84% | -1.24% | +71.10% | |
| 36 | NAUT | Nautilus Biotechnology INC | Stock-Other | 0.84% | +0.51% | +38.23% | |
| 37 | ABBV | Abbvie INC | Stock-Healthcare | 0.82% | — | — | |
| 38 | ✓ | Immatics NV | Stock-Other | 0.82% | — | — | |
| 39 | NBIX | Neurocrine Biosciences INC | Stock-Healthcare | 0.80% | -0.67% | +70.05% | |
| 40 | MDGL | Madrigal Pharmaceuticals INC | Stock-Healthcare | 0.78% | — | +21.27% | |
| 41 | CATBUSD | Astria Therapeutics INC | Stock-Other | 0.69% | -1.51% | EXIT | |
| 42 | ALDX | Aldeyra Therapeutics INC | Stock-Other | 0.67% | -0.39% | EXIT | |
| 43 | ADMA | Adma Biologics INC | Stock-Healthcare | 0.65% | — | -7.89% | |
| 44 | AMLX | Amylyx Pharmaceuticals INC | Stock-Other | 0.61% | — | -30.49% | |
| 45 | ✓ | Fusion Pharmaceuticals INC | Stock-Other | 0.59% | — | — | |
| 46 | TARS | Tarsus Pharmaceuticals INC | Stock-Other | 0.59% | — | — | |
| 47 | RVMD | Revolution Medicines INC | Stock-Healthcare | 0.52% | +0.49% | NEW | |
| 48 | AKRO | Akero Therapeutics INC | Stock-Other | 0.50% | — | -60.00% | |
| 49 | OBIO | Orchestra Biomed Holdings In | Stock-Other | 0.50% | — | — | |
| 50 | CELC | Celcuity INC | Stock-Other | 0.48% | +1.35% | — |