CIK: 0001224962
Total reported value
$5.1B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 6.68% | — | -8.31% | |
| 2 | BBIO | Bridgebio Pharma INC | Stock-Healthcare | 6.14% | — | — | |
| 3 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 5.19% | — | — | |
| 4 | TVTX 2.5 09-15-25 | Travere Therapeutics INC | Stock-Other | 4.99% | — | — | |
| 5 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 3.70% | — | +26.68% | |
| 6 | AM6 | Amicus Therapeutics INC | Stock-Other | 2.89% | -1.62% | EXIT | |
| 7 | COLL 2.625 02-15-26 | Collegium Pharma INC | Stock-Other | 2.46% | — | — | |
| 8 | ✓ | Horizon Therapeutics PLC | Stock-Other | 2.41% | — | -3.17% | |
| 9 | VAC2USD | Vbi Vaccines INC | Stock-Other | 2.39% | — | — | |
| 10 | ✓ | Landos Biopharma INC Com New | Stock-Other | 2.23% | — | — | |
| 11 | NVTA1EUR | Invitae CORP | Stock-Other | 2.11% | — | -10.11% | |
| 12 | NVRO 2.75 04-01-25 | Nevro CORP | Stock-Other | 2.03% | — | — | |
| 13 | ZYMEUSD | Zymeworks INC | Stock-Other | 1.94% | — | -0.58% | |
| 14 | GBTUSD | Global Blood Therapeutics In | Stock-Other | 1.89% | — | -17.91% | |
| 15 | NVROEUR | Nevro CORP | Stock-Other | 1.76% | — | +0.81% | |
| 16 | RCKT | Rocket Pharmaceuticals INC | Stock-Other | 1.58% | — | -4.05% | |
| 17 | OMGBP | Outset Medical INC | Stock-Other | 1.55% | — | — | |
| 18 | CERE1EUR | Cerevel Therapeutics Holding | Stock-Other | 1.54% | — | — | |
| 19 | ALDX | Aldeyra Therapeutics INC | Stock-Other | 1.46% | -0.39% | EXIT | |
| 20 | UTHR | United Therapeutics CORP | Stock-Healthcare | 1.44% | — | +252.46% | |
| 21 | MGTX | MeiraGTx Holdings plc | Stock-Other | 1.40% | — | +0.22% | |
| 22 | NAUT | Nautilus Biotechnology INC | Stock-Other | 1.17% | +0.51% | — | |
| 23 | CCCC | C4 Therapeutics INC | Stock-Other | 1.11% | — | -28.49% | |
| 24 | ✓ | Singular Genomics Systems In | Stock-Other | 1.10% | — | — | |
| 25 | BDQM | Albireo Pharma INC | Stock-Other | 1.08% | — | — | |
| 26 | ✓ | Stock-Other | 1.06% | — | — | ||
| 27 | NBIX | Neurocrine Biosciences INC | Stock-Healthcare | 1.03% | -0.67% | -13.80% | |
| 28 | ✓ | Rapt Therapeutics INC | Stock-Other | 1.02% | — | +1.74% | |
| 29 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 0.97% | — | +8.31% | |
| 30 | RLAY | Relay Therapeutics INC | Stock-Other | 0.96% | +1.61% | — | |
| 31 | BEAM | Beam Therapeutics INC | Stock-Other | 0.90% | — | — | |
| 32 | ZYUSD | Zymergen INC | Stock-Other | 0.85% | — | — | |
| 33 | CHRS | Coherus Oncology INC | Stock-Other | 0.84% | — | — | |
| 34 | ATNXEUR | Athenex INC | Stock-Other | 0.81% | — | — | |
| 35 | ✓ | Establishment Labs Hldgs INC | Stock-Other | 0.79% | — | -29.06% | |
| 36 | KDMN | Kadmon Holdings INC | Stock-Other | 0.79% | — | — | |
| 37 | KRON1USD | Kronos Bio INC | Stock-Other | 0.79% | — | -9.07% | |
| 38 | ✓ | Quotient LTD | Stock-Other | 0.77% | — | — | |
| 39 | MGNX | Macrogenics INC | Stock-Other | 0.75% | — | — | |
| 40 | MDT | Medtronic plc | Stock-Healthcare | 0.72% | — | — | |
| 41 | MORFUSD | Morphic Holding INC | Stock-Other | 0.70% | — | — | |
| 42 | SLDB | Solid Biosciences Inc. | Stock-Other | 0.64% | — | — | |
| 43 | AVIR | Atea Pharmaceuticals INC | Stock-Other | 0.63% | — | -27.34% | |
| 44 | CHRS 1.5 04-15-26 | Coherus Oncology INC | Stock-Other | 0.60% | — | — | |
| 45 | ✓ | Caremax INC | Stock-Other | 0.56% | — | — | |
| 46 | ✓ | Stock-Other | 0.55% | — | — | ||
| 47 | APLSUSD | Apellis Pharmaceuticals INC | Stock-Other | 0.54% | — | — | |
| 48 | ✓ | Verrica Pharmaceuticals INC | Stock-Other | 0.53% | — | — | |
| 49 | ✓ | Rain Oncology INC Com | Stock-Other | 0.51% | — | — | |
| 50 | TMCI | Treace Medical Concepts INC | Stock-Other | 0.50% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | MRTXEUR | Mirati Therapeutics INC | — | NEW | New buy |
| 2 | BBIO | Bridgebio Pharma INC | — | NEW | New buy |
| 3 | SWTXUSD | Springworks Therapeutics INC | — | NEW | New buy |
| 4 | TVTX 2.5 09-15-25 | Travere Therapeutics INC | — | NEW | New buy |
| 5 | IOVA | Iovance Biotherapeutics INC | — | NEW | New buy |
| 6 | AM6 | Amicus Therapeutics INC | — | NEW | New buy |
| 7 | COLL 2.625 02-15-26 | Collegium Pharma INC | — | NEW | New buy |
| 8 | ✓ | Horizon Therapeutics PLC | — | NEW | New buy |
| 9 | VAC2USD | Vbi Vaccines INC | — | NEW | New buy |
| 10 | ✓ | Landos Biopharma INC Com New | — | NEW | New buy |
| 11 | NVTA1EUR | Invitae CORP | — | NEW | New buy |
| 12 | NVRO 2.75 04-01-25 | Nevro CORP | — | NEW | New buy |
| 13 | ZYMEUSD | Zymeworks INC | — | NEW | New buy |
| 14 | GBTUSD | Global Blood Therapeutics In | — | NEW | New buy |
| 15 | NVROEUR | Nevro CORP | — | NEW | New buy |
| 16 | RCKT | Rocket Pharmaceuticals INC | — | NEW | New buy |
| 17 | OMGBP | Outset Medical INC | — | NEW | New buy |
| 18 | CERE1EUR | Cerevel Therapeutics Holding | — | NEW | New buy |
| 19 | ALDX | Aldeyra Therapeutics INC | — | NEW | New buy |
| 20 | UTHR | United Therapeutics CORP | — | NEW | New buy |
| 21 | MGTX | MeiraGTx Holdings plc | — | NEW | New buy |
| 22 | NAUT | Nautilus Biotechnology INC | — | NEW | New buy |
| 23 | CCCC | C4 Therapeutics INC | — | NEW | New buy |
| 24 | ✓ | Singular Genomics Systems In | — | NEW | New buy |
| 25 | BDQM | Albireo Pharma INC | — | NEW | New buy |
| 26 | ✓ | — | NEW | New buy | |
| 27 | NBIX | Neurocrine Biosciences INC | — | NEW | New buy |
| 28 | ✓ | Rapt Therapeutics INC | — | NEW | New buy |
| 29 | CRNX | Crinetics Pharmaceuticals In | — | NEW | New buy |
| 30 | RLAY | Relay Therapeutics INC | — | NEW | New buy |
| 31 | BEAM | Beam Therapeutics INC | — | NEW | New buy |
| 32 | ZYUSD | Zymergen INC | — | NEW | New buy |
| 33 | CHRS | Coherus Oncology INC | — | NEW | New buy |
| 34 | ATNXEUR | Athenex INC | — | NEW | New buy |
| 35 | ✓ | Establishment Labs Hldgs INC | — | NEW | New buy |
| 36 | KDMN | Kadmon Holdings INC | — | NEW | New buy |
| 37 | KRON1USD | Kronos Bio INC | — | NEW | New buy |
| 38 | ✓ | Quotient LTD | — | NEW | New buy |
| 39 | MGNX | Macrogenics INC | — | NEW | New buy |
| 40 | MDT | Medtronic plc | — | NEW | New buy |
| 41 | MORFUSD | Morphic Holding INC | — | NEW | New buy |
| 42 | SLDB | Solid Biosciences Inc. | — | NEW | New buy |
| 43 | AVIR | Atea Pharmaceuticals INC | — | NEW | New buy |
| 44 | CHRS 1.5 04-15-26 | Coherus Oncology INC | — | NEW | New buy |
| 45 | ✓ | Caremax INC | — | NEW | New buy |
| 46 | ✓ | — | NEW | New buy | |
| 47 | APLSUSD | Apellis Pharmaceuticals INC | — | NEW | New buy |
| 48 | ✓ | Verrica Pharmaceuticals INC | — | NEW | New buy |
| 49 | ✓ | Rain Oncology INC Com | — | NEW | New buy |
| 50 | TMCI | Treace Medical Concepts INC | — | NEW | New buy |