CIK: 0001055951
Total reported value
$5.0B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | SVA | Sinovac Biotech Ltd. | Stock-Other | 6.67% | — | — | |
| 2 | ELVN | Enliven Therapeutics INC | Stock-Other | 3.87% | +3.68% | — | |
| 3 | BSX | Boston Scientific CORP | Stock-Healthcare | 3.72% | -1.75% | -2.78% | |
| 4 | HUM | Humana INC | Stock-Healthcare | 3.32% | — | — | |
| 5 | BMY | Bristol-myers Squibb Co | Stock-Healthcare | 3.18% | — | -9.47% | |
| 6 | ISRG | Intuitive Surgical INC | Stock-Healthcare | 3.11% | -1.13% | — | |
| 7 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 3.08% | — | — | |
| 8 | ✓ | Theseus Pharmaceuticals INC | Stock-Other | 3.00% | — | — | |
| 9 | BIIB | Biogen INC | Stock-Healthcare | 2.76% | — | +95.58% | |
| 10 | UNH | Unitedhealth Group INC | Stock-Healthcare | 2.56% | — | -27.46% | |
| 11 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 2.54% | — | -3.31% | |
| 12 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 2.27% | — | -14.31% | |
| 13 | SYK | Stryker CORP | Stock-Healthcare | 2.06% | -1.14% | -23.58% | |
| 14 | EWTX | Edgewise Therapeutics INC | Stock-Other | 1.91% | +1.83% | — | |
| 15 | EVH | Evolent Health INC - A | Stock-Other | 1.84% | — | +2.51% | |
| 16 | 430 | Terns Pharmaceuticals INC | Stock-Other | 1.77% | -1.78% | EXIT | |
| 17 | VRNA | Verona Pharma PLC - Adr | Stock-Other | 1.68% | — | -6.81% | |
| 18 | TMO | Thermo Fisher Scientific INC | Stock-Healthcare | 1.67% | — | -26.90% | |
| 19 | BAX | Baxter International INC | Stock-Healthcare | 1.52% | — | — | |
| 20 | IONS | Ionis Pharmaceuticals INC | Stock-Healthcare | 1.49% | — | +6.57% | |
| 21 | CMPX | Compass Therapeutics INC | Stock-Other | 1.44% | — | — | |
| 22 | THC | Tenet Healthcare CORP | Stock-Healthcare | 1.42% | — | — | |
| 23 | KROS | Keros Therapeutics INC | Stock-Other | 1.41% | — | — | |
| 24 | LLY | Eli Lilly & Co | Stock-Healthcare | 1.25% | -2.29% | — | |
| 25 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 1.25% | — | +23.58% | |
| 26 | APLSUSD | Apellis Pharmaceuticals INC | Stock-Other | 1.18% | -1.25% | EXIT | |
| 27 | SIBN | Si-bone INC | Stock-Other | 1.13% | — | -13.32% | |
| 28 | PRLD | Prelude Therapeutics INC | Stock-Other | 1.12% | — | — | |
| 29 | SPRY | Ars Pharmaceuticals INC | Stock-Other | 1.12% | -0.65% | — | |
| 30 | VRTX | Vertex Pharmaceuticals INC | Stock-Healthcare | 1.10% | — | -34.59% | |
| 31 | NTRA | Natera INC | Stock-Healthcare | 1.06% | -0.67% | -49.98% | |
| 32 | ✓ | Ikena Oncology INC | Stock-Other | 1.06% | — | -2.08% | |
| 33 | EW | Edwards Lifesciences CORP | Stock-Healthcare | 1.02% | -1.52% | -26.79% | |
| 34 | SCPH | Scpharmaceuticals INC | Stock-Other | 0.99% | — | — | |
| 35 | NBIX | Neurocrine Biosciences INC | Stock-Healthcare | 0.97% | -0.91% | EXIT | |
| 36 | IRON | Disc Medicine INC | Stock-Other | 0.94% | -0.38% | +5.03% | |
| 37 | 290A | Chinook Therapeutics INC | Stock-Other | 0.92% | — | — | |
| 38 | XTNT | Xtant Medical Holdings INC | Stock-Other | 0.92% | — | — | |
| 39 | ✓ | Vectivbio Holding | Stock-Other | 0.86% | — | -26.41% | |
| 40 | TORCEUR | Adicet Bio INC | Stock-Other | 0.84% | — | — | |
| 41 | QURE | uniQure N.V. | Stock-Other | 0.82% | +0.33% | +18.13% | |
| 42 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 0.81% | +0.81% | — | |
| 43 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 0.78% | — | -17.14% | |
| 44 | TVTX | Travere Therapeutics INC | Stock-Other | 0.77% | — | +39.20% | |
| 45 | ✓ | Mersana Therapeutics INC | Stock-Other | 0.74% | — | +2.34% | |
| 46 | BLU | Bellus Health INC | Stock-Other | 0.72% | — | +8.49% | |
| 47 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 0.71% | +0.45% | NEW | |
| 48 | JANX | Janux Therapeutics INC | Stock-Other | 0.67% | — | — | |
| 49 | PGNY | Progyny INC | Stock-Other | 0.65% | — | +0.28% | |
| 50 | RPTX | Repare Therapeutics INC | Stock-Other | 0.64% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ELVN | Enliven Therapeutics INC | +3.9% | NEW | New buy |
| 2 | BAX | Baxter International INC | +1.5% | NEW | New buy |
| 3 | BIIB | Biogen INC | +1.4% | +95.58% | Add |
| 4 | ✓ | Theseus Pharmaceuticals INC | +1.4% | — | Unchanged |
| 5 | LLY | Eli Lilly & Co | +1.3% | NEW | New buy |
| 6 | APLSUSD | Apellis Pharmaceuticals INC | +1.2% | NEW | New buy |
| 7 | RCM1USD | R1 Rcm INC | +0.5% | NEW | New buy |
| 8 | AMLX | Amylyx Pharmaceuticals INC | +0.5% | NEW | New buy |
| 9 | XBI | Ss Spdr S&p Biotech ETF | +0.4% | +389.53% | Add |
| 10 | REGN | Regeneron Pharmaceuticals | +0.4% | NEW | New buy |
| 11 | AMGN | Amgen INC | +0.4% | NEW | New buy |
| 12 | EVH | Evolent Health INC - A | +0.3% | +2.51% | Add |
| 13 | ✓ | Apollomics INC | +0.3% | NEW | New buy |
| 14 | IOVA | Iovance Biotherapeutics INC | +0.3% | +134.50% | Add |
| 15 | TSVT* | 2seventy Bio INC | +0.3% | +129.68% | Add |
| 16 | 430 | Terns Pharmaceuticals INC | +0.3% | — | Unchanged |
| 17 | THC | Tenet Healthcare CORP | +0.3% | — | Unchanged |
| 18 | TVTX | Travere Therapeutics INC | +0.3% | +39.20% | Add |
| 19 | NPCE | Neuropace INC | +0.3% | — | Unchanged |
| 20 | SYK | Stryker CORP | -0.2% | -23.58% | Trim |
| 21 | EW | Edwards Lifesciences CORP | -0.2% | -26.79% | Trim |
| 22 | SNDX | Syndax Pharmaceuticals INC | -0.3% | -14.69% | Trim |
| 23 | ✓ | Mersana Therapeutics INC | -0.3% | +2.34% | Add |
| 24 | ✓ | -0.3% | +19.17% | Add | |
| 25 | MRNA | Moderna INC | -0.3% | EXIT | Sold out |
| 26 | RPTX | Repare Therapeutics INC | -0.3% | — | Unchanged |
| 27 | ARQT | Arcutis Biotherapeutics INC | -0.3% | -22.18% | Trim |
| 28 | ✓ | Vectivbio Holding | -0.3% | -26.41% | Trim |
| 29 | SPRY | Ars Pharmaceuticals INC | -0.3% | — | Unchanged |
| 30 | MRTXEUR | Mirati Therapeutics INC | -0.3% | -17.14% | Trim |
| 31 | SWTXUSD | Springworks Therapeutics INC | -0.3% | -14.31% | Trim |
| 32 | ✓ | Imara INC | -0.3% | EXIT | Sold out |
| 33 | ALXO | Alx Oncology Holdings INC | -0.4% | — | Unchanged |
| 34 | BMY | Bristol-myers Squibb Co | -0.4% | -9.47% | Trim |
| 35 | VRTX | Vertex Pharmaceuticals INC | -0.4% | -34.59% | Trim |
| 36 | TORCEUR | Adicet Bio INC | -0.4% | — | Unchanged |
| 37 | NTRA | Natera INC | -0.4% | -49.98% | Trim |
| 38 | ✓ | Cincor Pharma INC | -0.5% | EXIT | Sold out |
| 39 | TMO | Thermo Fisher Scientific INC | -0.5% | -26.90% | Trim |
| 40 | PMVP | Pmv Pharmaceuticals INC | -0.5% | — | Unchanged |
| 41 | EWTX | Edgewise Therapeutics INC | -0.6% | — | Unchanged |
| 42 | NBIX | Neurocrine Biosciences INC | -0.6% | -28.89% | Trim |
| 43 | VRNA | Verona Pharma PLC - Adr | -0.6% | -6.81% | Trim |
| 44 | PCVX | Vaxcyte INC | -0.6% | -43.15% | Trim |
| 45 | CMPX | Compass Therapeutics INC | -0.7% | — | Unchanged |
| 46 | ACRS | Aclaris Therapeutics INC | -0.8% | EXIT | Sold out |
| 47 | ETNBGBP | 89bio INC | -0.9% | EXIT | Sold out |
| 48 | UNH | Unitedhealth Group INC | -1.3% | -27.46% | Trim |
| 49 | PFE | Pfizer INC | -1.4% | EXIT | Sold out |
| 50 | SGENUSD | Seagen INC | -2.3% | EXIT | Sold out |