Avoro Capital Advisors LLC — Q2 2021 13F Holdings

Name: Avoro Capital Advisors LLC — 13F Holdings, Q2 2021
Creator: AlphaSMO
License: https://www.sec.gov/forms

CIK: 0001633313

Total reported value

$10.2B

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Full holdings list this quarter

#	Ticker	Issuer	Asset Subclass	Weight	Weight Change	Shares Change
1	✓	Horizon Therapeutics PLC	Stock-Other	14.66%	—	—
2	MRTXEUR	Mirati Therapeutics INC	Stock-Other	14.05%	—	+6.95%
3	UTHR	United Therapeutics CORP	Stock-Healthcare	9.36%	+2.96%	—
4	XLRN	Acceleron Pharma INC	Stock-Other	6.55%	—	—
5	ARGX	Argenx Se - Adr	Stock-Healthcare	4.96%	-1.00%	+2.27%
6	ARNAEUR	Arena Pharmaceuticals INC	Stock-Other	4.83%	—	+0.62%
7	ASND	Ascendis Pharma A/S	Stock-Other	4.35%	+0.67%	—
8	IOVA	Iovance Biotherapeutics INC	Stock-Other	4.12%	—	+13.75%
9	SRPT	Sarepta Therapeutics INC	Stock-Healthcare	3.25%	—	+11.63%
10	ALNY	Alnylam Pharmaceuticals INC	Stock-Healthcare	2.97%	—	—
11	VRTX	Vertex Pharmaceuticals INC	Stock-Healthcare	2.77%	—	-43.57%
12	MDGL	Madrigal Pharmaceuticals INC	Stock-Healthcare	2.41%	-0.99%	—
13	BMRN	Biomarin Pharmaceutical INC	Stock-Healthcare	2.39%	—	—
14	AM6	Amicus Therapeutics INC	Stock-Other	2.09%	—	+1.63%
15	CNST	Constellation Pharmaceutical	Stock-Other	1.89%	—	+8.81%
16	✓	Mersana Therapeutics INC	Stock-Other	1.61%	—	—
17	KURA	Kura Oncology INC	Stock-Other	1.50%	—	+3.50%
18	XENE	Xenon Pharmaceuticals INC	Stock-Other	1.18%	+0.92%	—
19	APLSUSD	Apellis Pharmaceuticals INC	Stock-Other	1.16%	+1.82%	+24.52%
20	PMVP	Pmv Pharmaceuticals INC	Stock-Other	1.08%	—	-22.68%
21	GLUE	Monte Rosa Therapeutics INC	Stock-Other	1.08%	—	—
22	ACAD	Acadia Pharmaceuticals INC	Stock-Healthcare	1.04%	—	-2.33%
23	MRNS*	Marinus Pharmaceuticals INC	Stock-Other	1.01%	—	—
24	TREUR	Trillium Therapeutics INC	Stock-Other	0.96%	—	—
25	SNDX	Syndax Pharmaceuticals INC	Stock-Other	0.90%	—	+20.00%
26	MNKD	Mannkind CORP	Stock-Other	0.82%	-0.20%	+15.07%
27	CBAYUSD	Cymabay Therapeutics INC	Stock-Other	0.78%	—	—
28	OPHTEUR	Iveric Bio INC	Stock-Other	0.71%	—	-11.38%
29	DCPHEUR	Deciphera Pharmaceuticals In	Stock-Other	0.68%	—	+19.60%
30	RLMD	Relmada Therapeutics INC	Stock-Other	0.52%	—	-38.69%
31	✓	Avadel Pharmaceuticals PLC	Stock-Other	0.51%	—	—
32	PRAX	Praxis Precision Medicines, Inc.	Stock-Other	0.51%	—	+0.22%
33	DSGN	Design Therapeutics INC	Stock-Other	0.46%	—	—
34	✓	Amarin Corp PLC	Stock-Other	0.46%	—	—
35	OLMA	Olema Pharmaceuticals INC	Stock-Other	0.43%	—	—
36	ADVMCHF	Adverum Biotechnologies INC	Stock-Other	0.42%	—	-13.13%
37	✓	Merus N V	Stock-Other	0.24%	—	-0.75%
38	RNAGBP	Avidity Biosciences INC	Stock-Other	0.23%	-3.87%	EXIT
39	FENC	Fennec Pharmaceuticals INC	Stock-Other	0.21%	—	—
40	GNCAQ	Genocea Biosciences INC	Stock-Other	0.21%	—	—
41	260	Centessa Pharmaceuticals-adr	Stock-Other	0.19%	+0.89%	—
42	✓	Bctg Acquisition CORP	Stock-Other	0.16%	—	—
43	ADAPY	Adaptimmune Therapeutics-adr	Stock-Other	0.15%	—	-42.97%
44	✓	Aerpio Pharmaceuticals INC Com	Stock-Other	0.13%	—	—

Holding changes this quarter

Position changes disclosed by Avoro Capital Advisors LLC for the quarter ending Q2 2021, including ticker, issuer, weight change, shares change, and action
#	Ticker	Issuer	Weight Change	Shares Change	Action
1	✓	Horizon Therapeutics PLC	—	EXIT	Sold out
2	MRTXEUR	Mirati Therapeutics INC	—	EXIT	Sold out
3	UTHR	United Therapeutics CORP	—	EXIT	Sold out
4	XLRN	Acceleron Pharma INC	—	EXIT	Sold out
5	VRTX	Vertex Pharmaceuticals INC	—	EXIT	Sold out
6	ARNAEUR	Arena Pharmaceuticals INC	—	EXIT	Sold out
7	ARGX	Argenx Se - Adr	—	EXIT	Sold out
8	IOVA	Iovance Biotherapeutics INC	—	EXIT	Sold out
9	✓	Ascendis Pharma	—	EXIT	Sold out
10	MDGL	Madrigal Pharmaceuticals INC	—	EXIT	Sold out
11	SRPT	Sarepta Therapeutics INC	—	EXIT	Sold out
12	BMRN	Biomarin Pharmaceutical INC	—	EXIT	Sold out
13	AM6	Amicus Therapeutics INC	—	EXIT	Sold out
14	KURA	Kura Oncology INC	—	EXIT	Sold out
15	✓	Mersana Therapeutics INC	—	EXIT	Sold out
16	ADVMCHF	Adverum Biotechnologies INC	—	EXIT	Sold out
17	PMVP	Pmv Pharmaceuticals INC	—	EXIT	Sold out
18	CNST	Constellation Pharmaceutical	—	EXIT	Sold out
19	XENE	Xenon Pharmaceuticals INC	—	EXIT	Sold out
20	ACAD	Acadia Pharmaceuticals INC	—	EXIT	Sold out
21	TREUR	Trillium Therapeutics INC	—	EXIT	Sold out
22	SNDX	Syndax Pharmaceuticals INC	—	EXIT	Sold out
23	RLMD	Relmada Therapeutics INC	—	EXIT	Sold out
24	MRNS*	Marinus Pharmaceuticals INC	—	EXIT	Sold out
25	PRAX	Praxis Precision Medicines, Inc.	—	EXIT	Sold out
26	CBAYUSD	Cymabay Therapeutics INC	—	EXIT	Sold out
27	OPHTEUR	Iveric Bio INC	—	EXIT	Sold out
28	APLSUSD	Apellis Pharmaceuticals INC	—	EXIT	Sold out
29	DCPHEUR	Deciphera Pharmaceuticals In	—	EXIT	Sold out
30	DSGN	Design Therapeutics INC	—	EXIT	Sold out
31	✓	Avadel Pharmaceuticals PLC	—	EXIT	Sold out
32	✓	Amarin Corp PLC	—	EXIT	Sold out
33	TVTX	Travere Therapeutics INC	—	EXIT	Sold out
34	MNKD	Mannkind CORP	—	EXIT	Sold out
35	OLMA	Olema Pharmaceuticals INC	—	EXIT	Sold out
36	ADAPY	Adaptimmune Therapeutics-adr	—	EXIT	Sold out
37	RLAY	Relay Therapeutics INC	—	EXIT	Sold out
38	✓	Merus N V	—	EXIT	Sold out
39	GNCAQ	Genocea Biosciences INC	—	EXIT	Sold out
40	RNAGBP	Avidity Biosciences INC	—	EXIT	Sold out
41	BDTX	Black Diamond Therapeutics I	—	EXIT	Sold out
42	✓	Therapeutics Acquisition Cor	—	EXIT	Sold out
43	FENC	Fennec Pharmaceuticals INC	—	EXIT	Sold out
44	✓	Bctg Acquisition CORP	—	EXIT	Sold out
45	JNCEEUR	Jounce Therapeutics INC	—	EXIT	Sold out
46	LKFT	Lakefront Biotherapeutic-adr	—	EXIT	Sold out