CIK: 0001633313
Total reported value
$10.2B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | IMMU | Immunomedics INC | Stock-Other | 31.71% | — | — | |
| 2 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 10.25% | — | +1.31% | |
| 3 | ✓ | Horizon Therapeutics PLC | Stock-Other | 8.44% | — | +27.50% | |
| 4 | IOVA | Iovance Biotherapeutics INC | Stock-Other | 4.46% | — | -7.96% | |
| 5 | ASND | Ascendis Pharma A/S | Stock-Other | 3.95% | +0.67% | +2.86% | |
| 6 | MYOKEUR | Myokardia INC | Stock-Other | 3.65% | — | +0.27% | |
| 7 | ARGX | Argenx Se - Adr | Stock-Healthcare | 3.37% | -1.00% | -6.96% | |
| 8 | SRPT | Sarepta Therapeutics INC | Stock-Healthcare | 3.34% | — | — | |
| 9 | ARNAEUR | Arena Pharmaceuticals INC | Stock-Other | 3.29% | — | +226.32% | |
| 10 | AM6 | Amicus Therapeutics INC | Stock-Other | 2.18% | — | -1.36% | |
| 11 | XLRN | Acceleron Pharma INC | Stock-Other | 2.16% | — | +29.81% | |
| 12 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 1.89% | — | -5.41% | |
| 13 | ✓ | Mersana Therapeutics INC | Stock-Other | 1.80% | — | +4.62% | |
| 14 | MDGL | Madrigal Pharmaceuticals INC | Stock-Healthcare | 1.50% | -0.99% | +154.29% | |
| 15 | DCPHEUR | Deciphera Pharmaceuticals In | Stock-Other | 1.33% | — | -2.15% | |
| 16 | ADAPY | Adaptimmune Therapeutics-adr | Stock-Other | 1.25% | — | +7.84% | |
| 17 | KPTIEUR | Karyopharm Therapeutics INC | Stock-Other | 1.24% | — | -14.29% | |
| 18 | CNST | Constellation Pharmaceutical | Stock-Other | 1.23% | — | +6.88% | |
| 19 | ADVMCHF | Adverum Biotechnologies INC | Stock-Other | 1.17% | — | +5.47% | |
| 20 | TREUR | Trillium Therapeutics INC | Stock-Other | 1.11% | — | +15.79% | |
| 21 | KURA | Kura Oncology INC | Stock-Other | 1.06% | — | +131.90% | |
| 22 | CBAYUSD | Cymabay Therapeutics INC | Stock-Other | 1.06% | — | +96.19% | |
| 23 | QURE | uniQure N.V. | Stock-Other | 0.92% | -0.49% | +16.67% | |
| 24 | PMVP | Pmv Pharmaceuticals INC | Stock-Other | 0.82% | — | — | |
| 25 | RLMD | Relmada Therapeutics INC | Stock-Other | 0.80% | — | +5.26% | |
| 26 | OPHTEUR | Iveric Bio INC | Stock-Other | 0.58% | — | +2.11% | |
| 27 | ATNXEUR | Athenex INC | Stock-Other | 0.56% | — | -15.19% | |
| 28 | MRNSUSD | Marinus Pharmaceuticals INC | Stock-Other | 0.55% | — | -74.92% | |
| 29 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 0.44% | +0.92% | — | |
| 30 | CUE1EUR | Cue Biopharma INC | Stock-Other | 0.40% | — | — | |
| 31 | ALT | Altimmune INC | Stock-Other | 0.38% | — | — | |
| 32 | ✓ | Amarin Corp PLC | Stock-Other | 0.36% | — | +200.00% | |
| 33 | RTRXEUR | Retrophin INC | Stock-Other | 0.35% | — | +26.19% | |
| 34 | RLAY | Relay Therapeutics INC | Stock-Other | 0.30% | — | — | |
| 35 | ✓ | Avadel Pharmaceuticals PLC | Stock-Other | 0.30% | — | -8.01% | |
| 36 | ✓ | Rapt Therapeutics INC | Stock-Other | 0.26% | — | — | |
| 37 | BDTX | Black Diamond Therapeutics I | Stock-Other | 0.26% | — | +14.76% | |
| 38 | ZGNXEUR | Zogenix INC | Stock-Other | 0.22% | — | -61.11% | |
| 39 | RNAGBP | Avidity Biosciences INC | Stock-Other | 0.22% | -3.87% | EXIT | |
| 40 | ✓ | Therapeutics Acquisition Cor | Stock-Other | 0.20% | — | — | |
| 41 | GNCAQ | Genocea Biosciences INC | Stock-Other | 0.17% | — | — | |
| 42 | 2662247D | Iteos Therapeutics INC | Stock-Other | 0.16% | — | — | |
| 43 | FENC | Fennec Pharmaceuticals INC | Stock-Other | 0.14% | — | — | |
| 44 | ✓ | Bctg Acquisition CORP | Stock-Other | 0.12% | — | — | |
| 45 | ✓ | Alimera Sciences INC | Stock-Other | 0.03% | — | — | |
| 46 | KYMR | Kymera Therapeutics INC | Stock-Other | 0.02% | +0.40% | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | IMMU | Immunomedics INC | +13.3% | — | Unchanged |
| 2 | ARNAEUR | Arena Pharmaceuticals INC | +2.1% | +226.32% | Add |
| 3 | ✓ | Horizon Therapeutics PLC | +1.9% | +27.50% | Add |
| 4 | MDGL | Madrigal Pharmaceuticals INC | +0.7% | +154.29% | Add |
| 5 | KURA | Kura Oncology INC | +0.7% | +131.90% | Add |
| 6 | CBAYUSD | Cymabay Therapeutics INC | +0.7% | +96.19% | Add |
| 7 | MRTXEUR | Mirati Therapeutics INC | +0.6% | +1.31% | Add |
| 8 | TREUR | Trillium Therapeutics INC | +0.4% | +15.79% | Add |
| 9 | XLRN | Acceleron Pharma INC | +0.2% | +29.81% | Add |
| 10 | ✓ | Amarin Corp PLC | +0.1% | +200.00% | Add |
| 11 | MYOKEUR | Myokardia INC | +0.1% | +0.27% | Add |
| 12 | MRNSUSD | Marinus Pharmaceuticals INC | -0.1% | -74.92% | Trim |
| 13 | RTRXEUR | Retrophin INC | -0.1% | +26.19% | Add |
| 14 | OPHTEUR | Iveric Bio INC | -0.1% | +2.11% | Add |
| 15 | FENC | Fennec Pharmaceuticals INC | -0.1% | — | Unchanged |
| 16 | BDTX | Black Diamond Therapeutics I | -0.2% | +14.76% | Add |
| 17 | XENE | Xenon Pharmaceuticals INC | -0.3% | — | Unchanged |
| 18 | QURE | uniQure N.V. | -0.4% | +16.67% | Add |
| 19 | ✓ | Avadel Pharmaceuticals PLC | -0.4% | -8.01% | Trim |
| 20 | RLMD | Relmada Therapeutics INC | -0.5% | +5.26% | Add |
| 21 | ATNXEUR | Athenex INC | -0.5% | -15.19% | Trim |
| 22 | CUE1EUR | Cue Biopharma INC | -0.5% | — | Unchanged |
| 23 | ADAPY | Adaptimmune Therapeutics-adr | -0.7% | +7.84% | Add |
| 24 | DCPHEUR | Deciphera Pharmaceuticals In | -0.9% | -2.15% | Trim |
| 25 | ARGX | Argenx Se - Adr | -1% | -6.96% | Trim |
| 26 | ZGNXEUR | Zogenix INC | -1% | -61.11% | Trim |
| 27 | AM6 | Amicus Therapeutics INC | -1.1% | -1.36% | Trim |
| 28 | CNST | Constellation Pharmaceutical | -1.2% | +6.88% | Add |
| 29 | IOVA | Iovance Biotherapeutics INC | -1.2% | -7.96% | Trim |
| 30 | ASND | Ascendis Pharma A/S | -1.2% | +2.86% | Add |
| 31 | ✓ | Mersana Therapeutics INC | -1.2% | +4.62% | Add |
| 32 | KPTIEUR | Karyopharm Therapeutics INC | -1.4% | -14.29% | Trim |
| 33 | ADVMCHF | Adverum Biotechnologies INC | -2% | +5.47% | Add |
| 34 | SRPT | Sarepta Therapeutics INC | -2% | — | Unchanged |
| 35 | BMRN | Biomarin Pharmaceutical INC | -2.6% | -5.41% | Trim |
| 36 | PMVP | Pmv Pharmaceuticals INC | — | NEW | New buy |
| 37 | ALLO | Allogene Therapeutics INC | — | EXIT | Sold out |
| 38 | AUPH | Aurinia Pharmaceuticals INC | — | EXIT | Sold out |
| 39 | ALT | Altimmune INC | — | NEW | New buy |
| 40 | RLAY | Relay Therapeutics INC | — | NEW | New buy |
| 41 | ✓ | Rapt Therapeutics INC | — | NEW | New buy |
| 42 | 1T7 | Tricida INC | — | EXIT | Sold out |
| 43 | PTCT | Ptc Therapeutics INC | — | EXIT | Sold out |
| 44 | ✓ | Therapeutics Acquisition Cor | — | NEW | New buy |
| 45 | GNCAQ | Genocea Biosciences INC | — | NEW | New buy |
| 46 | 2662247D | Iteos Therapeutics INC | — | NEW | New buy |
| 47 | RVMD | Revolution Medicines INC | — | EXIT | Sold out |
| 48 | BDSIUSD | Biodelivery Sciences Intl | — | EXIT | Sold out |
| 49 | ✓ | Bctg Acquisition CORP | — | NEW | New buy |
| 50 | CRDF | Cardiff Oncology INC | — | EXIT | Sold out |