CIK: 0001306923
Total reported value
$653.9M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ABMDEUR | Abiomed INC | Stock-Other | 11.93% | — | -2.73% | |
| 2 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 11.60% | -0.25% | +0.40% | |
| 3 | UTHR | United Therapeutics CORP | Stock-Healthcare | 9.46% | +1.75% | +0.42% | |
| 4 | STAA | Staar Surgical Co | Stock-Other | 7.05% | — | +17.79% | |
| 5 | ALXN | Alexion Pharmaceuticals INC | Stock-Other | 6.24% | — | +0.34% | |
| 6 | VNDA | Vanda Pharmaceuticals INC | Stock-Other | 5.78% | — | — | |
| 7 | INSM | Insmed INC | Stock-Healthcare | 5.35% | -1.47% | +4.03% | |
| 8 | CLVSEUR | Clovis Oncology INC | Stock-Other | 5.01% | — | +0.35% | |
| 9 | SG7 | Sage Therapeutics INC | Stock-Other | 4.34% | — | +1.26% | |
| 10 | ✓ | Wright Medical Group NV | Stock-Other | 4.02% | — | +0.50% | |
| 11 | IMMU | Immunomedics INC | Stock-Other | 3.94% | — | +3.44% | |
| 12 | AM6 | Amicus Therapeutics INC | Stock-Other | 3.77% | -7.86% | +16.26% | |
| 13 | AMAG | Amag Pharmaceuticals INC | Stock-Other | 2.73% | — | — | |
| 14 | KPTIEUR | Karyopharm Therapeutics INC | Stock-Other | 2.34% | — | +0.47% | |
| 15 | EPZMEUR | Epizyme INC | Stock-Other | 2.27% | — | +0.42% | |
| 16 | CELG | Celgene CORP | Stock-Other | 1.82% | — | +24.09% | |
| 17 | AIMT | Aimmune Therapeutics INC | Stock-Other | 1.77% | — | +0.42% | |
| 18 | ALGN | Align Technology INC | Stock-Healthcare | 1.75% | +0.19% | +6.10% | |
| 19 | ACAD | Acadia Pharmaceuticals INC | Stock-Healthcare | 1.74% | +0.54% | +20.30% | |
| 20 | PBYI | Puma Biotechnology INC | Stock-Other | 1.26% | — | — | |
| 21 | MNTA | Momenta Pharmaceuticals INC | Stock-Other | 1.08% | — | +0.44% | |
| 22 | EXK | Exact Sciences CORP | Stock-Materials | 1.06% | — | +0.50% | |
| 23 | ALDR1EUR | Alder Biopharmaceuticals INC | Stock-Other | 1.02% | — | +0.46% | |
| 24 | PRTA | Prothena Corporation plc | Stock-Other | 0.61% | +0.04% | +0.47% | |
| 25 | GILD | Gilead Sciences INC | Stock-Healthcare | 0.59% | — | — | |
| 26 | RIGLUSD | Rigel Pharmaceuticals INC | Stock-Other | 0.49% | — | +0.50% | |
| 27 | ✓ | Shire PLC | Stock-Other | 0.44% | — | -75.13% | |
| 28 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 0.29% | — | — | |
| 29 | ALIMEUR | Alimera Sciences INC | Stock-Other | 0.12% | — | — | |
| 30 | ZGNXEUR | Zogenix INC | Stock-Other | 0.06% | — | — | |
| 31 | CYTK | Cytokinetics INC | Stock-Healthcare | 0.04% | +0.32% | NEW | |
| 32 | SNSSEUR | Viracta Therapeutics INC | Stock-Other | 0.03% | — | — | |
| 33 | ✓ | Idera Pharmaceuticals INC | Stock-Other | 0.01% | — | — | |
| 34 | SPHSEUR | Sophiris Bio INC | Stock-Other | 0.01% | — | — | |
| 35 | ✓ | Melinta Therapeutics Inc | Stock-Other | — | — | — | |
| 36 | ✓ | Histogenics CORP | Stock-Other | — | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | VNDA | Vanda Pharmaceuticals INC | +1.9% | — | Unchanged |
| 2 | BMRN | Biomarin Pharmaceutical INC | +1.6% | +0.40% | Add |
| 3 | UTHR | United Therapeutics CORP | +1.1% | +0.42% | Add |
| 4 | ✓ | Wright Medical Group NV | +0.8% | +0.50% | Add |
| 5 | AM6 | Amicus Therapeutics INC | +0.7% | +16.26% | Add |
| 6 | ACAD | Acadia Pharmaceuticals INC | +0.3% | +20.30% | Add |
| 7 | CELG | Celgene CORP | +0.3% | +24.09% | Add |
| 8 | AIMT | Aimmune Therapeutics INC | +0.3% | +0.42% | Add |
| 9 | STAA | Staar Surgical Co | +0.2% | +17.79% | Add |
| 10 | EXK | Exact Sciences CORP | +0.1% | +0.50% | Add |
| 11 | GILD | Gilead Sciences INC | 0% | — | Unchanged |
| 12 | PRTA | Prothena Corporation plc | 0% | +0.47% | Add |
| 13 | AMAG | Amag Pharmaceuticals INC | — | — | Unchanged |
| 14 | ALIMEUR | Alimera Sciences INC | — | — | Unchanged |
| 15 | ZGNXEUR | Zogenix INC | — | — | Unchanged |
| 16 | CYTK | Cytokinetics INC | 0% | — | Unchanged |
| 17 | ✓ | Melinta Therapeutics Inc | 0% | — | Unchanged |
| 18 | ✓ | Histogenics CORP | 0% | — | Unchanged |
| 19 | RIGLUSD | Rigel Pharmaceuticals INC | 0% | +0.50% | Add |
| 20 | DRNAUSD | Dicerna Pharmaceuticals INC | 0% | — | Unchanged |
| 21 | SPHSEUR | Sophiris Bio INC | 0% | — | Unchanged |
| 22 | ✓ | Idera Pharmaceuticals INC | 0% | — | Unchanged |
| 23 | SNSSEUR | Viracta Therapeutics INC | -0.1% | — | Unchanged |
| 24 | ALDR1EUR | Alder Biopharmaceuticals INC | -0.2% | +0.46% | Add |
| 25 | IMMU | Immunomedics INC | -0.3% | +3.44% | Add |
| 26 | SG7 | Sage Therapeutics INC | -0.5% | +1.26% | Add |
| 27 | ALXN | Alexion Pharmaceuticals INC | -0.5% | +0.34% | Add |
| 28 | ALGN | Align Technology INC | -0.6% | +6.10% | Add |
| 29 | INSM | Insmed INC | -0.7% | +4.03% | Add |
| 30 | EPZMEUR | Epizyme INC | -0.7% | +0.42% | Add |
| 31 | KPTIEUR | Karyopharm Therapeutics INC | -0.9% | +0.47% | Add |
| 32 | MNTA | Momenta Pharmaceuticals INC | -0.9% | +0.44% | Add |
| 33 | ABMDEUR | Abiomed INC | -1% | -2.73% | Trim |
| 34 | ✓ | Shire PLC | -1% | -75.13% | Trim |
| 35 | CLVSEUR | Clovis Oncology INC | -1.2% | +0.35% | Add |
| 36 | PBYI | Puma Biotechnology INC | — | NEW | New buy |
| 37 | ✓ | Trevena INC | — | EXIT | Sold out |