CIK: 0001306923
Total reported value
$653.9M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ABMDEUR | Abiomed INC | Stock-Other | 17.06% | — | -11.14% | |
| 2 | UTHR | United Therapeutics CORP | Stock-Healthcare | 13.75% | +1.75% | +12.65% | |
| 3 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 10.21% | -0.25% | +29.62% | |
| 4 | AMAG | Amag Pharmaceuticals INC | Stock-Other | 5.91% | — | +12.63% | |
| 5 | CLVSEUR | Clovis Oncology INC | Stock-Other | 3.94% | — | +9.90% | |
| 6 | INSM | Insmed INC | Stock-Healthcare | 3.76% | -1.47% | +5.51% | |
| 7 | VNDA | Vanda Pharmaceuticals INC | Stock-Other | 3.57% | — | +4.83% | |
| 8 | ACAD | Acadia Pharmaceuticals INC | Stock-Healthcare | 3.53% | +0.54% | +196.38% | |
| 9 | ✓ | Cempra INC | Stock-Other | 3.47% | — | +129.27% | |
| 10 | ✓ | Wright Medical Group NV | Stock-Other | 3.16% | — | +9.92% | |
| 11 | ALXN | Alexion Pharmaceuticals INC | Stock-Other | 2.99% | — | — | |
| 12 | ✓ | Zeltiq Aesthetics INC | Stock-Other | 2.87% | — | +142.50% | |
| 13 | EPZMEUR | Epizyme INC | Stock-Other | 2.10% | — | +2.11% | |
| 14 | CELG | Celgene CORP | Stock-Other | 2.08% | — | +3.25% | |
| 15 | PRTA | Prothena Corporation plc | Stock-Other | 2.08% | +0.04% | +13.39% | |
| 16 | GILD | Gilead Sciences INC | Stock-Healthcare | 2.01% | — | +5.12% | |
| 17 | ✓ | Shire PLC | Stock-Other | 1.66% | — | +12.44% | |
| 18 | AM6 | Amicus Therapeutics INC | Stock-Other | 1.65% | -7.86% | +12.90% | |
| 19 | KPTIEUR | Karyopharm Therapeutics INC | Stock-Other | 1.59% | — | +1.33% | |
| 20 | ✓ | Ariad Pharmaceuticals INC | Stock-Other | 1.42% | — | +12.76% | |
| 21 | STAA | Staar Surgical Co | Stock-Other | 1.33% | — | +21.40% | |
| 22 | MNTA | Momenta Pharmaceuticals INC | Stock-Other | 1.33% | — | +10.91% | |
| 23 | MODV | ModivCare Inc. | Stock-Other | 1.25% | — | -47.86% | |
| 24 | ✓ | Heartware Intl INC | Stock-Other | 1.19% | — | +8.38% | |
| 25 | ✓ | Stock-Other | 1.09% | — | +11.42% | ||
| 26 | SG7 | Sage Therapeutics INC | Stock-Other | 0.95% | — | — | |
| 27 | RIGLUSD | Rigel Pharmaceuticals INC | Stock-Other | 0.91% | — | +2.97% | |
| 28 | ✓ | Sequenom INC | Stock-Other | 0.71% | — | +2.98% | |
| 29 | EXK | Exact Sciences CORP | Stock-Materials | 0.37% | — | — | |
| 30 | ACRXUSD | Acelrx Pharmaceuticals INC | Stock-Other | 0.29% | — | — | |
| 31 | ✓ | Sunesis Pharmaceuticals INC | Stock-Other | 0.29% | — | — | |
| 32 | ALIMEUR | Alimera Sciences INC | Stock-Other | 0.28% | — | — | |
| 33 | AIMT | Aimmune Therapeutics INC | Stock-Other | 0.27% | — | — | |
| 34 | ALGN | Align Technology INC | Stock-Healthcare | 0.22% | +0.19% | +30.98% | |
| 35 | ✓ | Idera Pharmaceuticals INC | Stock-Other | 0.15% | — | — | |
| 36 | ✓ | Alcobra Ltd | Stock-Other | 0.09% | — | +7.32% | |
| 37 | CYTK | Cytokinetics INC | Stock-Healthcare | 0.09% | +0.32% | NEW | |
| 38 | XONUSD | Intrexon CORP | Stock-Other | 0.09% | — | — | |
| 39 | SPHSEUR | Sophiris Bio INC | Stock-Other | 0.08% | — | — | |
| 40 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 0.06% | — | — | |
| 41 | ✓ | Histogenics CORP | Stock-Other | 0.06% | — | — | |
| 42 | ✓ | Orexigen Therapeutics INC | Stock-Other | 0.05% | — | — | |
| 43 | ZGNXEUR | Zogenix INC | Stock-Other | 0.02% | — | +3.15% | |
| 44 | QURE | uniQure N.V. | Stock-Other | 0.01% | — | — | |
| 45 | MRNSUSD | Marinus Pharmaceuticals INC | Stock-Other | 0.01% | — | +7.62% |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ACAD | Acadia Pharmaceuticals INC | +2.5% | +196.38% | Add |
| 2 | ✓ | Cempra INC | +1.8% | +129.27% | Add |
| 3 | ✓ | Zeltiq Aesthetics INC | +1.7% | +142.50% | Add |
| 4 | BMRN | Biomarin Pharmaceutical INC | +1.6% | +29.62% | Add |
| 5 | VNDA | Vanda Pharmaceuticals INC | +1% | +4.83% | Add |
| 6 | AMAG | Amag Pharmaceuticals INC | +0.6% | +12.63% | Add |
| 7 | ✓ | Heartware Intl INC | +0.6% | +8.38% | Add |
| 8 | UTHR | United Therapeutics CORP | +0.6% | +12.65% | Add |
| 9 | ✓ | Wright Medical Group NV | +0.3% | +9.92% | Add |
| 10 | ✓ | Ariad Pharmaceuticals INC | +0.3% | +12.76% | Add |
| 11 | MNTA | Momenta Pharmaceuticals INC | +0.3% | +10.91% | Add |
| 12 | ✓ | Shire PLC | +0.2% | +12.44% | Add |
| 13 | EXK | Exact Sciences CORP | +0.2% | — | Unchanged |
| 14 | RIGLUSD | Rigel Pharmaceuticals INC | +0.1% | +2.97% | Add |
| 15 | ALGN | Align Technology INC | +0.1% | +30.98% | Add |
| 16 | SPHSEUR | Sophiris Bio INC | 0% | — | Unchanged |
| 17 | CYTK | Cytokinetics INC | 0% | — | Unchanged |
| 18 | ✓ | Alcobra Ltd | 0% | +7.32% | Add |
| 19 | ✓ | Sunesis Pharmaceuticals INC | — | — | Unchanged |
| 20 | ZGNXEUR | Zogenix INC | — | +3.15% | Add |
| 21 | MRNSUSD | Marinus Pharmaceuticals INC | 0% | +7.62% | Add |
| 22 | QURE | uniQure N.V. | 0% | — | Unchanged |
| 23 | CELG | Celgene CORP | 0% | +3.25% | Add |
| 24 | ✓ | Histogenics CORP | 0% | — | Unchanged |
| 25 | ✓ | Orexigen Therapeutics INC | 0% | — | Unchanged |
| 26 | XONUSD | Intrexon CORP | 0% | — | Unchanged |
| 27 | ✓ | Idera Pharmaceuticals INC | 0% | — | Unchanged |
| 28 | DRNAUSD | Dicerna Pharmaceuticals INC | -0.1% | — | Unchanged |
| 29 | ACRXUSD | Acelrx Pharmaceuticals INC | -0.1% | — | Unchanged |
| 30 | ABMDEUR | Abiomed INC | -0.1% | -11.14% | Trim |
| 31 | AIMT | Aimmune Therapeutics INC | -0.1% | — | Unchanged |
| 32 | ALIMEUR | Alimera Sciences INC | -0.1% | — | Unchanged |
| 33 | PRTA | Prothena Corporation plc | -0.1% | +13.39% | Add |
| 34 | GILD | Gilead Sciences INC | -0.2% | +5.12% | Add |
| 35 | STAA | Staar Surgical Co | -0.2% | +21.40% | Add |
| 36 | ✓ | Sequenom INC | -0.4% | +2.98% | Add |
| 37 | EPZMEUR | Epizyme INC | -0.4% | +2.11% | Add |
| 38 | KPTIEUR | Karyopharm Therapeutics INC | -0.6% | +1.33% | Add |
| 39 | MODV | ModivCare Inc. | -0.6% | -47.86% | Trim |
| 40 | AM6 | Amicus Therapeutics INC | -0.7% | +12.90% | Add |
| 41 | ✓ | -0.7% | +11.42% | Add | |
| 42 | INSM | Insmed INC | -1% | +5.51% | Add |
| 43 | CLVSEUR | Clovis Oncology INC | -1.2% | +9.90% | Add |
| 44 | ✓ | Anacor Pharmaceuticals INC | — | EXIT | Sold out |
| 45 | ALXN | Alexion Pharmaceuticals INC | — | NEW | New buy |
| 46 | SG7 | Sage Therapeutics INC | — | NEW | New buy |