CIK: 0001306923
Total reported value
$653.9M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ABMDEUR | Abiomed INC | Stock-Other | 17.12% | — | -19.50% | |
| 2 | UTHR | United Therapeutics CORP | Stock-Healthcare | 13.20% | +1.75% | +0.46% | |
| 3 | ✓ | Anacor Pharmaceuticals INC | Stock-Other | 9.21% | — | +1.45% | |
| 4 | BMRN | Biomarin Pharmaceutical INC | Stock-Healthcare | 8.58% | -0.25% | +0.26% | |
| 5 | AMAG | Amag Pharmaceuticals INC | Stock-Other | 5.28% | — | +2.48% | |
| 6 | CLVSEUR | Clovis Oncology INC | Stock-Other | 5.16% | — | -2.43% | |
| 7 | INSM | Insmed INC | Stock-Healthcare | 4.71% | -1.47% | — | |
| 8 | ✓ | Wright Medical Group NV | Stock-Other | 2.82% | — | +2.76% | |
| 9 | VNDA | Vanda Pharmaceuticals INC | Stock-Other | 2.62% | — | — | |
| 10 | EPZMEUR | Epizyme INC | Stock-Other | 2.50% | — | -0.21% | |
| 11 | AM6 | Amicus Therapeutics INC | Stock-Other | 2.33% | -7.86% | — | |
| 12 | PRTA | Prothena Corporation plc | Stock-Other | 2.22% | +0.04% | — | |
| 13 | GILD | Gilead Sciences INC | Stock-Healthcare | 2.16% | — | — | |
| 14 | KPTIEUR | Karyopharm Therapeutics INC | Stock-Other | 2.15% | — | -0.47% | |
| 15 | CELG | Celgene CORP | Stock-Other | 2.10% | — | — | |
| 16 | MODV | ModivCare Inc. | Stock-Other | 1.88% | — | +3.06% | |
| 17 | ✓ | Stock-Other | 1.81% | — | +3.42% | ||
| 18 | ✓ | Cempra INC | Stock-Other | 1.65% | — | +3.41% | |
| 19 | STAA | Staar Surgical Co | Stock-Other | 1.52% | — | -0.93% | |
| 20 | ✓ | Shire PLC | Stock-Other | 1.42% | — | +1.34% | |
| 21 | ✓ | Zeltiq Aesthetics INC | Stock-Other | 1.21% | — | — | |
| 22 | ✓ | Ariad Pharmaceuticals INC | Stock-Other | 1.12% | — | -0.39% | |
| 23 | ✓ | Sequenom INC | Stock-Other | 1.10% | — | — | |
| 24 | MNTA | Momenta Pharmaceuticals INC | Stock-Other | 1.05% | — | — | |
| 25 | ACAD | Acadia Pharmaceuticals INC | Stock-Healthcare | 1.05% | +0.54% | — | |
| 26 | RIGLUSD | Rigel Pharmaceuticals INC | Stock-Other | 0.84% | — | -0.16% | |
| 27 | ✓ | Heartware Intl INC | Stock-Other | 0.61% | — | +2.36% | |
| 28 | ALIMEUR | Alimera Sciences INC | Stock-Other | 0.41% | — | — | |
| 29 | AIMT | Aimmune Therapeutics INC | Stock-Other | 0.34% | — | — | |
| 30 | ACRXUSD | Acelrx Pharmaceuticals INC | Stock-Other | 0.34% | — | — | |
| 31 | ✓ | Sunesis Pharmaceuticals INC | Stock-Other | 0.29% | — | — | |
| 32 | EXK | Exact Sciences CORP | Stock-Materials | 0.21% | — | — | |
| 33 | ✓ | Idera Pharmaceuticals INC | Stock-Other | 0.19% | — | — | |
| 34 | ALGN | Align Technology INC | Stock-Healthcare | 0.16% | +0.19% | — | |
| 35 | XONUSD | Intrexon CORP | Stock-Other | 0.12% | — | — | |
| 36 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 0.11% | — | — | |
| 37 | ✓ | Histogenics CORP | Stock-Other | 0.08% | — | — | |
| 38 | ✓ | Alcobra Ltd | Stock-Other | 0.07% | — | — | |
| 39 | ✓ | Orexigen Therapeutics INC | Stock-Other | 0.07% | — | — | |
| 40 | CYTK | Cytokinetics INC | Stock-Healthcare | 0.07% | +0.32% | NEW | |
| 41 | SPHSEUR | Sophiris Bio INC | Stock-Other | 0.06% | — | — | |
| 42 | MRNSUSD | Marinus Pharmaceuticals INC | Stock-Other | 0.02% | — | — | |
| 43 | ZGNXEUR | Zogenix INC | Stock-Other | 0.02% | — | — | |
| 44 | QURE | uniQure N.V. | Stock-Other | 0.02% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ABMDEUR | Abiomed INC | +2.6% | -19.50% | Trim |
| 2 | BMRN | Biomarin Pharmaceutical INC | +0.8% | +0.26% | Add |
| 3 | VNDA | Vanda Pharmaceuticals INC | +0.5% | — | Unchanged |
| 4 | AMAG | Amag Pharmaceuticals INC | +0.5% | +2.48% | Add |
| 5 | MODV | ModivCare Inc. | +0.5% | +3.06% | Add |
| 6 | STAA | Staar Surgical Co | +0.5% | -0.93% | Trim |
| 7 | GILD | Gilead Sciences INC | +0.5% | — | Unchanged |
| 8 | AM6 | Amicus Therapeutics INC | +0.4% | — | Unchanged |
| 9 | ✓ | Ariad Pharmaceuticals INC | +0.3% | -0.39% | Trim |
| 10 | CELG | Celgene CORP | +0.3% | — | Unchanged |
| 11 | ✓ | Zeltiq Aesthetics INC | +0.3% | — | Unchanged |
| 12 | ✓ | Shire PLC | +0.2% | +1.34% | Add |
| 13 | ✓ | Sequenom INC | +0.2% | — | Unchanged |
| 14 | EPZMEUR | Epizyme INC | +0.1% | -0.21% | Trim |
| 15 | ALGN | Align Technology INC | +0.1% | — | Unchanged |
| 16 | XONUSD | Intrexon CORP | 0% | — | Unchanged |
| 17 | ACRXUSD | Acelrx Pharmaceuticals INC | 0% | — | Unchanged |
| 18 | AIMT | Aimmune Therapeutics INC | 0% | — | Unchanged |
| 19 | EXK | Exact Sciences CORP | 0% | — | Unchanged |
| 20 | SPHSEUR | Sophiris Bio INC | 0% | — | Unchanged |
| 21 | ALIMEUR | Alimera Sciences INC | — | — | Unchanged |
| 22 | CYTK | Cytokinetics INC | — | — | Unchanged |
| 23 | ZGNXEUR | Zogenix INC | — | — | Unchanged |
| 24 | QURE | uniQure N.V. | — | — | Unchanged |
| 25 | ✓ | Histogenics CORP | 0% | — | Unchanged |
| 26 | MRNSUSD | Marinus Pharmaceuticals INC | 0% | — | Unchanged |
| 27 | ✓ | Alcobra Ltd | 0% | — | Unchanged |
| 28 | ✓ | Idera Pharmaceuticals INC | 0% | — | Unchanged |
| 29 | UTHR | United Therapeutics CORP | 0% | +0.46% | Add |
| 30 | RIGLUSD | Rigel Pharmaceuticals INC | 0% | -0.16% | Trim |
| 31 | ✓ | Wright Medical Group NV | -0.1% | +2.76% | Add |
| 32 | ✓ | Sunesis Pharmaceuticals INC | -0.1% | — | Unchanged |
| 33 | DRNAUSD | Dicerna Pharmaceuticals INC | -0.1% | — | Unchanged |
| 34 | ✓ | Heartware Intl INC | -0.1% | +2.36% | Add |
| 35 | ✓ | Orexigen Therapeutics INC | -0.1% | — | Unchanged |
| 36 | INSM | Insmed INC | -0.1% | — | Unchanged |
| 37 | KPTIEUR | Karyopharm Therapeutics INC | -0.2% | -0.47% | Trim |
| 38 | MNTA | Momenta Pharmaceuticals INC | -0.2% | — | Unchanged |
| 39 | ✓ | Cempra INC | -0.4% | +3.41% | Add |
| 40 | PRTA | Prothena Corporation plc | -0.4% | — | Unchanged |
| 41 | ✓ | -0.9% | +3.42% | Add | |
| 42 | CLVSEUR | Clovis Oncology INC | -1.8% | -2.43% | Trim |
| 43 | ✓ | Anacor Pharmaceuticals INC | -4.5% | +1.45% | Add |
| 44 | ACAD | Acadia Pharmaceuticals INC | — | NEW | New buy |