CIK: 0001595855
Total reported value
$759.2M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | OCUL | Ocular Therapeutix INC | Stock-Other | 8.91% | -1.88% | — | |
| 2 | TARA | Protara Therapeutic INC | Stock-Other | 8.42% | — | +15.85% | |
| 3 | ETON | Eton Pharmaceuticals INC | Stock-Other | 5.62% | +2.92% | — | |
| 4 | CRDF | Cardiff Oncology INC | Stock-Other | 4.81% | — | +193.49% | |
| 5 | AFIB | Acutus Medical INC | Stock-Other | 4.37% | — | — | |
| 6 | CCXIEUR | Chemocentryx INC | Stock-Other | 3.82% | — | -1.55% | |
| 7 | ✓ | Neoleukin Therapeutics INC | Stock-Other | 3.25% | — | -0.98% | |
| 8 | HROW | Harrow INC | Stock-Other | 3.23% | -12.10% | +9.19% | |
| 9 | CDXS | Codexis INC | Stock-Other | 3.21% | — | — | |
| 10 | EIDXGBP | Eidos Therapeutics INC | Stock-Other | 3.12% | — | — | |
| 11 | PCVX | Vaxcyte INC | Stock-Other | 3.02% | — | — | |
| 12 | CLDX | Celldex Therapeutics INC | Stock-Other | 2.88% | — | -7.38% | |
| 13 | MGNX | Macrogenics INC | Stock-Other | 2.60% | — | +5.19% | |
| 14 | DCPHEUR | Deciphera Pharmaceuticals In | Stock-Other | 2.23% | — | — | |
| 15 | STXS | Stereotaxis INC | Stock-Other | 2.12% | — | -13.96% | |
| 16 | ✓ | Stock-Other | 2.11% | — | -42.52% | ||
| 17 | ✓ | Avenue Therapeutics INC | Stock-Other | 2.09% | — | -4.86% | |
| 18 | TGTX | Tg Therapeutics INC | Stock-Healthcare | 2.04% | +0.24% | -14.59% | |
| 19 | ✓ | Stock-Other | 2.04% | — | — | ||
| 20 | ✓ | Stock-Other | 2.01% | — | — | ||
| 21 | ✓ | Myovant Sciences LTD | Stock-Other | 1.88% | — | — | |
| 22 | CMRXEUR | Chimerix INC | Stock-Other | 1.87% | — | +82.49% | |
| 23 | MCRB1EUR | Seres Therapeutics INC | Stock-Other | 1.86% | — | — | |
| 24 | ✓ | Axovant Gene THE | Stock-Other | 1.84% | — | — | |
| 25 | KNSA | Kiniksa Pharmaceuticals International, plc | Stock-Other | 1.72% | — | -1.89% | |
| 26 | XOMA | Xoma Royalty Corporation | Stock-Other | 1.68% | +0.21% | +9.54% | |
| 27 | ✓ | Cerecor INC | Stock-Other | 1.50% | — | — | |
| 28 | BHVN | Biohaven Ltd. | Stock-Other | 1.45% | — | — | |
| 29 | ADMSEUR | Adamas Pharmaceuticals INC | Stock-Other | 1.20% | — | +54.98% | |
| 30 | FGENEUR | Fibrogen INC | Stock-Other | 1.18% | — | +0.68% | |
| 31 | TELA | Tela Bio INC | Stock-Other | 1.17% | — | +44.83% | |
| 32 | 4XC1 | Kalvista Pharmaceuticals INC | Stock-Other | 1.15% | — | +1.89% | |
| 33 | MEIPUSD | Lite Strategy INC | Stock-Other | 0.95% | — | — | |
| 34 | FOCL | Edap Tms SA -adr | Stock-Other | 0.94% | — | -44.64% | |
| 35 | CYTK | Cytokinetics INC | Stock-Healthcare | 0.88% | — | -31.10% | |
| 36 | CRNX | Crinetics Pharmaceuticals In | Stock-Other | 0.74% | — | -44.85% | |
| 37 | FULC | Fulcrum Therapeutics INC | Stock-Other | 0.70% | — | — | |
| 38 | 4NX1 | Lumos Pharma INC | Stock-Other | 0.65% | — | — | |
| 39 | ✓ | Stock-Other | 0.64% | — | — | ||
| 40 | ✓ | Veralto CORP | Stock-Other | 0.63% | — | — | |
| 41 | ✓ | Cidara Therapeutics INC Com New | Stock-Other | 0.54% | — | — | |
| 42 | AGLEUSD | Aeglea Biotherapeutics INC | Stock-Other | 0.52% | — | — | |
| 43 | NERVGBP | Minerva Neurosciences INC | Stock-Other | 0.48% | — | — | |
| 44 | OMGBP | Outset Medical INC | Stock-Other | 0.44% | — | — | |
| 45 | EPIEUR | Essa Pharma INC | Stock-Other | 0.37% | — | +55.06% | |
| 46 | STRO | Sutro Biopharma, Inc. | Stock-Other | 0.29% | — | — | |
| 47 | CFRXUSD | Contrafect CORP | Stock-Other | 0.23% | — | — | |
| 48 | CNCEEUR | Concert Pharmaceuticals INC | Stock-Other | 0.19% | — | — | |
| 49 | ✓ | Amarin Corp PLC | Stock-Other | 0.19% | — | -50.55% | |
| 50 | ASNSUSD | X4 Pharmaceuticals INC | Stock-Other | 0.10% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | CRDF | Cardiff Oncology INC | +4.2% | +193.49% | Add |
| 2 | ETON | Eton Pharmaceuticals INC | +1.6% | — | Unchanged |
| 3 | ADMSEUR | Adamas Pharmaceuticals INC | +0.7% | +54.98% | Add |
| 4 | CMRXEUR | Chimerix INC | +0.6% | +82.49% | Add |
| 5 | TELA | Tela Bio INC | +0.5% | +44.83% | Add |
| 6 | HROW | Harrow INC | +0.4% | +9.19% | Add |
| 7 | TGTX | Tg Therapeutics INC | +0.2% | -14.59% | Trim |
| 8 | EIDXGBP | Eidos Therapeutics INC | +0.2% | — | Unchanged |
| 9 | CLDX | Celldex Therapeutics INC | +0.1% | -7.38% | Trim |
| 10 | ✓ | Cidara Therapeutics INC Com New | -0.2% | — | Unchanged |
| 11 | BHVN | Biohaven Ltd. | -0.2% | — | Unchanged |
| 12 | ✓ | Cerecor INC | -0.3% | — | Unchanged |
| 13 | MEIPUSD | Lite Strategy INC | -0.4% | — | Unchanged |
| 14 | CCXIEUR | Chemocentryx INC | -0.4% | -1.55% | Trim |
| 15 | DCPHEUR | Deciphera Pharmaceuticals In | -0.4% | — | Unchanged |
| 16 | ✓ | Amarin Corp PLC | -0.5% | -50.55% | Trim |
| 17 | CYTK | Cytokinetics INC | -0.6% | -31.10% | Trim |
| 18 | CRNX | Crinetics Pharmaceuticals In | -0.8% | -44.85% | Trim |
| 19 | ✓ | Myovant Sciences LTD | -1% | — | Unchanged |
| 20 | STXS | Stereotaxis INC | -1% | -13.96% | Trim |
| 21 | OCUL | Ocular Therapeutix INC | -1.2% | — | Unchanged |
| 22 | ✓ | Neoleukin Therapeutics INC | -1.4% | -0.98% | Trim |
| 23 | ✓ | -1.9% | -42.52% | Trim | |
| 24 | TARA | Protara Therapeutic INC | -4.7% | +15.85% | Add |
| 25 | AFIB | Acutus Medical INC | — | NEW | New buy |
| 26 | PCVX | Vaxcyte INC | — | NEW | New buy |
| 27 | ✓ | Odonate Therapeu | — | EXIT | Sold out |
| 28 | ✓ | — | NEW | New buy | |
| 29 | MCRB1EUR | Seres Therapeutics INC | — | NEW | New buy |
| 30 | ✓ | Axovant Gene THE | — | NEW | New buy |
| 31 | QURE | uniQure N.V. | — | EXIT | Sold out |
| 32 | ✓ | Molecular Templates Inc | — | EXIT | Sold out |
| 33 | 1T7 | Tricida INC | — | EXIT | Sold out |
| 34 | CPRX | Catalyst Pharmaceuticals INC | — | EXIT | Sold out |
| 35 | BTAIEUR | Bioxcel Therapeutics INC | — | EXIT | Sold out |
| 36 | ✓ | Kala Bio INC Com New | — | EXIT | Sold out |
| 37 | FULC | Fulcrum Therapeutics INC | — | NEW | New buy |
| 38 | LQDA | Liquidia CORP | — | EXIT | Sold out |
| 39 | 4NX1 | Lumos Pharma INC | — | NEW | New buy |
| 40 | ✓ | — | NEW | New buy | |
| 41 | ARDX | Ardelyx INC | — | EXIT | Sold out |
| 42 | ✓ | Veralto CORP | — | NEW | New buy |
| 43 | AGLEUSD | Aeglea Biotherapeutics INC | — | NEW | New buy |
| 44 | NERVGBP | Minerva Neurosciences INC | — | NEW | New buy |
| 45 | OMGBP | Outset Medical INC | — | NEW | New buy |
| 46 | STRO | Sutro Biopharma, Inc. | — | NEW | New buy |
| 47 | FENC | Fennec Pharmaceuticals INC | — | EXIT | Sold out |
| 48 | CFRXUSD | Contrafect CORP | — | NEW | New buy |
| 49 | CNCEEUR | Concert Pharmaceuticals INC | — | NEW | New buy |
| 50 | AUTL | Autolus Therapeutics PLC | — | EXIT | Sold out |