CIK: 0001595855
Total reported value
$759.2M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | AXGN | Axogen INC | Stock-Other | 17.90% | — | -12.94% | |
| 2 | 2655787D | Blueprint Medicines CORP | Stock-Other | 15.73% | — | -18.37% | |
| 3 | ✓ | Loxo Oncology INC | Stock-Other | 5.92% | — | +1.76% | |
| 4 | CDXS | Codexis INC | Stock-Other | 5.35% | — | — | |
| 5 | FGENEUR | Fibrogen INC | Stock-Other | 4.76% | — | — | |
| 6 | ✓ | Strongbridge Biopharma PLC | Stock-Other | 4.02% | — | +27.20% | |
| 7 | ✓ | Corium Intl INC | Stock-Other | 3.49% | — | +0.47% | |
| 8 | AGIO | Agios Pharmaceuticals INC | Stock-Other | 3.04% | — | — | |
| 9 | FENC | Fennec Pharmaceuticals INC | Stock-Other | 3.02% | — | +3.08% | |
| 10 | SGMOQ | Sangamo Therapeutics INC | Stock-Other | 2.91% | — | -7.76% | |
| 11 | CBAYUSD | Cymabay Therapeutics INC | Stock-Other | 2.47% | — | — | |
| 12 | AMAG 2.5 02-15-19 | Amag Pharmaceuticals INC | Stock-Other | 2.42% | — | — | |
| 13 | ✓ | Miragen Therapeutics INC | Stock-Other | 2.12% | — | — | |
| 14 | DCPHEUR | Deciphera Pharmaceuticals In | Stock-Other | 2.09% | — | — | |
| 15 | ✓ | Ocular Therapeutix INC | Stock-Other | 2.07% | — | — | |
| 16 | XOMA | Xoma Royalty Corporation | Stock-Other | 1.85% | +0.21% | — | |
| 17 | ✓ | Biofrontera AG | Stock-Other | 1.85% | — | — | |
| 18 | ARDX | Ardelyx INC | Stock-Other | 1.64% | — | +26.18% | |
| 19 | BOLDEUR | Audentes Therapeutics INC | Stock-Other | 1.63% | — | -9.52% | |
| 20 | ✓ | Amarin Corp PLC | Stock-Other | 1.50% | — | +102.91% | |
| 21 | ✓ | Ablynx NV | Stock-Other | 1.40% | — | -78.57% | |
| 22 | ✓ | Foamix Pharmaceuticals LTD | Stock-Other | 1.39% | — | -1.04% | |
| 23 | VKTX | Viking Therapeutics INC | Stock-Healthcare | 1.38% | — | +129.07% | |
| 24 | RARE | Ultragenyx Pharmaceutical In | Stock-Other | 1.17% | — | -11.11% | |
| 25 | ACHNEUR | Achillion Pharmaceuticals | Stock-Other | 1.16% | — | +148.89% | |
| 26 | ✓ | Depomed INC | Stock-Other | 1.13% | — | — | |
| 27 | PTCT | Ptc Therapeutics INC | Stock-Healthcare | 1.12% | — | — | |
| 28 | TGTX | Tg Therapeutics INC | Stock-Healthcare | 1.11% | +0.24% | — | |
| 29 | SNDX | Syndax Pharmaceuticals INC | Stock-Other | 0.91% | — | — | |
| 30 | CMRXEUR | Chimerix INC | Stock-Other | 0.89% | — | — | |
| 31 | QTRX | Quanterix CORP | Stock-Other | 0.73% | — | +130.77% | |
| 32 | PLX1EUR | Protalix Biotherapeutics INC | Stock-Other | 0.50% | — | +78.63% | |
| 33 | ✓ | Stock-Other | 0.41% | — | — | ||
| 34 | EPZMEUR | Epizyme INC | Stock-Other | 0.36% | — | — | |
| 35 | SYRSEUR | Syros Pharmaceuticals INC | Stock-Other | 0.27% | — | — | |
| 36 | ZSANGBP | Zosano Pharma CORP | Stock-Other | 0.14% | — | — | |
| 37 | ✓ | Quotient LTD | Stock-Other | 0.08% | — | — | |
| 38 | ✓ | Biolinerx Ltd-spons Adr | Stock-Other | 0.06% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ✓ | Loxo Oncology INC | +1.2% | +1.76% | Add |
| 2 | ✓ | Strongbridge Biopharma PLC | +1.1% | +27.20% | Add |
| 3 | CDXS | Codexis INC | +0.8% | — | Unchanged |
| 4 | VKTX | Viking Therapeutics INC | +0.8% | +129.07% | Add |
| 5 | ACHNEUR | Achillion Pharmaceuticals | +0.8% | +148.89% | Add |
| 6 | AGIO | Agios Pharmaceuticals INC | +0.7% | — | Unchanged |
| 7 | CBAYUSD | Cymabay Therapeutics INC | +0.5% | — | Unchanged |
| 8 | ✓ | Amarin Corp PLC | +0.4% | +102.91% | Add |
| 9 | FENC | Fennec Pharmaceuticals INC | +0.3% | +3.08% | Add |
| 10 | QTRX | Quanterix CORP | +0.3% | +130.77% | Add |
| 11 | ✓ | Corium Intl INC | +0.2% | +0.47% | Add |
| 12 | PLX1EUR | Protalix Biotherapeutics INC | +0.1% | +78.63% | Add |
| 13 | AXGN | Axogen INC | +0.1% | -12.94% | Trim |
| 14 | SYRSEUR | Syros Pharmaceuticals INC | 0% | — | Unchanged |
| 15 | CMRXEUR | Chimerix INC | — | — | Unchanged |
| 16 | ✓ | Biolinerx Ltd-spons Adr | 0% | — | Unchanged |
| 17 | SGMOQ | Sangamo Therapeutics INC | -0.1% | -7.76% | Trim |
| 18 | RARE | Ultragenyx Pharmaceutical In | -0.2% | -11.11% | Trim |
| 19 | ARDX | Ardelyx INC | -0.3% | +26.18% | Add |
| 20 | ✓ | Foamix Pharmaceuticals LTD | -0.5% | -1.04% | Trim |
| 21 | BOLDEUR | Audentes Therapeutics INC | -0.5% | -9.52% | Trim |
| 22 | FGENEUR | Fibrogen INC | -0.7% | — | Unchanged |
| 23 | XOMA | Xoma Royalty Corporation | -1.8% | — | Unchanged |
| 24 | ✓ | Ablynx NV | -2% | -78.57% | Trim |
| 25 | 2655787D | Blueprint Medicines CORP | -2% | -18.37% | Trim |
| 26 | IMMU | Immunomedics INC | — | EXIT | Sold out |
| 27 | AMAG 2.5 02-15-19 | Amag Pharmaceuticals INC | — | NEW | New buy |
| 28 | ✓ | Miragen Therapeutics INC | — | NEW | New buy |
| 29 | DCPHEUR | Deciphera Pharmaceuticals In | — | NEW | New buy |
| 30 | ✓ | Ocular Therapeutix INC | — | NEW | New buy |
| 31 | CRSP | CRISPR Therapeutics AG | — | EXIT | Sold out |
| 32 | ✓ | Biofrontera AG | — | NEW | New buy |
| 33 | ARGX | Argenx Se - Adr | — | EXIT | Sold out |
| 34 | NKTREUR | Nektar Therapeutics | — | EXIT | Sold out |
| 35 | ✓ | Inotek Pharmaceuticals CORP | — | EXIT | Sold out |
| 36 | XLRN | Acceleron Pharma INC | — | EXIT | Sold out |
| 37 | ✓ | Depomed INC | — | NEW | New buy |
| 38 | PTCT | Ptc Therapeutics INC | — | NEW | New buy |
| 39 | TGTX | Tg Therapeutics INC | — | NEW | New buy |
| 40 | SNDX | Syndax Pharmaceuticals INC | — | NEW | New buy |
| 41 | DERMEUR | Dermira INC | — | EXIT | Sold out |
| 42 | QURE | uniQure N.V. | — | EXIT | Sold out |
| 43 | ✓ | — | NEW | New buy | |
| 44 | EPZMEUR | Epizyme INC | — | NEW | New buy |
| 45 | RYTM | Rhythm Pharmaceuticals INC | — | EXIT | Sold out |
| 46 | SPPIUSD | Spectrum Pharmaceuticals INC | — | EXIT | Sold out |
| 47 | ZSANGBP | Zosano Pharma CORP | — | NEW | New buy |
| 48 | ✓ | Quotient LTD | — | NEW | New buy |