CIK: 0001595855
Total reported value
$759.2M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | 2655787D | Blueprint Medicines CORP | Stock-Other | 14.54% | — | +12.10% | |
| 2 | AXGN | Axogen INC | Stock-Other | 10.45% | — | -1.50% | |
| 3 | ✓ | Ariad Pharmaceuticals INC | Stock-Other | 7.33% | — | -4.31% | |
| 4 | GNMXEUR | Aevi Genomic Medicine INC | Stock-Other | 4.58% | — | — | |
| 5 | FGENEUR | Fibrogen INC | Stock-Other | 4.16% | — | — | |
| 6 | ✓ | Foamix Pharmaceuticals LTD | Stock-Other | 3.24% | — | -21.43% | |
| 7 | AGIO | Agios Pharmaceuticals INC | Stock-Other | 3.20% | — | — | |
| 8 | CMRXEUR | Chimerix INC | Stock-Other | 3.17% | — | +50.00% | |
| 9 | CDXS | Codexis INC | Stock-Other | 3.17% | — | — | |
| 10 | ✓ | Aquinox Pharmaceuticals INC Bc | Stock-Other | 3.02% | — | — | |
| 11 | TBPH | Theravance Biopharma, Inc. | Stock-Other | 2.97% | — | — | |
| 12 | MNTA | Momenta Pharmaceuticals INC | Stock-Other | 2.93% | — | — | |
| 13 | ADMSEUR | Adamas Pharmaceuticals INC | Stock-Other | 2.84% | — | +14.00% | |
| 14 | CARAEUR | Cara Therapeutics INC | Stock-Other | 2.60% | — | -29.63% | |
| 15 | PRTA | Prothena Corporation plc | Stock-Other | 2.39% | — | +65.00% | |
| 16 | ✓ | Loxo Oncology INC | Stock-Other | 2.37% | — | +13.64% | |
| 17 | EGRX | Eagle Pharmaceuticals INC | Stock-Other | 2.34% | — | -28.57% | |
| 18 | EWTX | Edgewise Therapeutics, Inc. | Stock-Other | 2.06% | — | — | |
| 19 | MGNX | Macrogenics INC | Stock-Other | 2.05% | — | +17.24% | |
| 20 | XENE | Xenon Pharmaceuticals INC | Stock-Other | 1.84% | — | -1.22% | |
| 21 | ENTA | Enanta Pharmaceuticals INC | Stock-Other | 1.78% | — | — | |
| 22 | ✓ | Strongbridge Biopharma PLC | Stock-Other | 1.64% | — | — | |
| 23 | OMER | Omeros CORP | Stock-Other | 1.55% | — | — | |
| 24 | CLSDUSD | Clearside Biomedical INC | Stock-Other | 1.42% | — | — | |
| 25 | LION | Lionsgate Studios Corp. | Stock-Other | 1.23% | — | +7.14% | |
| 26 | ABEO1EUR | Abeona Therapeutics INC | Stock-Other | 1.14% | — | +300.00% | |
| 27 | CTMX | Cytomx Therapeutics INC | Stock-Other | 1.10% | — | +6.25% | |
| 28 | PTIEUR | Proteostasis Therapeutics In | Stock-Other | 1.08% | — | -1.32% | |
| 29 | ✓ | Imprimis Pharma Immy | Stock-Other | 1.06% | — | -40.76% | |
| 30 | SG7 | Sage Therapeutics INC | Stock-Other | 1.05% | — | — | |
| 31 | ✓ | Neuroderm LTD | Stock-Other | 1.02% | — | +16.75% | |
| 32 | ✓ | Wafergen Bio-systems INC | Stock-Other | 0.93% | — | — | |
| 33 | ✓ | Corium Intl INC | Stock-Other | 0.91% | — | -5.00% | |
| 34 | SGMOQ | Sangamo Therapeutics INC | Stock-Other | 0.72% | — | — | |
| 35 | AKAOQ | Achaogen INC | Stock-Other | 0.61% | — | — | |
| 36 | PLX 4.5 09-15-18 | Protalix Biotherapeautic | Stock-Other | 0.51% | — | -76.08% | |
| 37 | OCUL | Ocular Therapeutix INC | Stock-Other | 0.46% | -1.88% | — | |
| 38 | TREUR | Trillium Therapeutics INC | Stock-Other | 0.37% | — | -37.14% | |
| 39 | ✓ | Biolinerx Ltd-spons Adr | Stock-Other | 0.14% | — | — | |
| 40 | AGRXUSD | Agile Therapeutics INC | Stock-Other | 0.05% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | 2655787D | Blueprint Medicines CORP | +2.3% | +12.10% | Add |
| 2 | AXGN | Axogen INC | +1% | -1.50% | Trim |
| 3 | CMRXEUR | Chimerix INC | +0.9% | +50.00% | Add |
| 4 | ✓ | Loxo Oncology INC | +0.9% | +13.64% | Add |
| 5 | ✓ | Aquinox Pharmaceuticals INC Bc | +0.9% | — | Unchanged |
| 6 | ABEO1EUR | Abeona Therapeutics INC | +0.8% | +300.00% | Add |
| 7 | PRTA | Prothena Corporation plc | +0.8% | +65.00% | Add |
| 8 | ADMSEUR | Adamas Pharmaceuticals INC | +0.7% | +14.00% | Add |
| 9 | FGENEUR | Fibrogen INC | +0.6% | — | Unchanged |
| 10 | EWTX | Edgewise Therapeutics, Inc. | +0.5% | — | Unchanged |
| 11 | ✓ | Foamix Pharmaceuticals LTD | +0.2% | -21.43% | Trim |
| 12 | ✓ | Ariad Pharmaceuticals INC | -0.2% | -4.31% | Trim |
| 13 | PTIEUR | Proteostasis Therapeutics In | -0.2% | -1.32% | Trim |
| 14 | CTMX | Cytomx Therapeutics INC | -0.2% | +6.25% | Add |
| 15 | EGRX | Eagle Pharmaceuticals INC | -0.2% | -28.57% | Trim |
| 16 | MGNX | Macrogenics INC | -0.2% | +17.24% | Add |
| 17 | ✓ | Corium Intl INC | -0.3% | -5.00% | Trim |
| 18 | CARAEUR | Cara Therapeutics INC | -0.4% | -29.63% | Trim |
| 19 | AGIO | Agios Pharmaceuticals INC | -0.4% | — | Unchanged |
| 20 | TREUR | Trillium Therapeutics INC | -1% | -37.14% | Trim |
| 21 | ✓ | Imprimis Pharma Immy | -1.4% | -40.76% | Trim |
| 22 | PLX 4.5 09-15-18 | Protalix Biotherapeautic | -1.9% | -76.08% | Trim |
| 23 | ✓ | Medgenics Inc New | — | EXIT | Sold out |
| 24 | GNMXEUR | Aevi Genomic Medicine INC | — | NEW | New buy |
| 25 | TBPH | Theravance Biopharma, Inc. | — | NEW | New buy |
| 26 | CTH | Cynapsus Therapeutics INC | — | EXIT | Sold out |
| 27 | ✓ | Horizon Pharma PLC | — | EXIT | Sold out |
| 28 | MNTA | Momenta Pharmaceuticals INC | — | NEW | New buy |
| 29 | GBTUSD | Global Blood Therapeutics In | — | EXIT | Sold out |
| 30 | IMMU | Immunomedics INC | — | EXIT | Sold out |
| 31 | RCKT 5 02-15-20 | Rocket Pharmaceuticals | — | EXIT | Sold out |
| 32 | ENTA | Enanta Pharmaceuticals INC | — | NEW | New buy |
| 33 | ✓ | Strongbridge Biopharma PLC | — | NEW | New buy |
| 34 | OMER | Omeros CORP | — | NEW | New buy |
| 35 | ✓ | Zogenix INC | — | EXIT | Sold out |
| 36 | RARE | Ultragenyx Pharmaceutical In | — | EXIT | Sold out |
| 37 | CLSDUSD | Clearside Biomedical INC | — | NEW | New buy |
| 38 | ✓ | Amarin Corp PLC | — | EXIT | Sold out |
| 39 | SG7 | Sage Therapeutics INC | — | NEW | New buy |
| 40 | ✓ | Nabriva Therapeutics AG | — | EXIT | Sold out |
| 41 | ✓ | Wafergen Bio-systems INC | — | NEW | New buy |
| 42 | ✓ | Innocoll Hldgs PLC | — | EXIT | Sold out |
| 43 | SGMOQ | Sangamo Therapeutics INC | — | NEW | New buy |
| 44 | AFRM | Affirm Holdings, Inc. | — | EXIT | Sold out |
| 45 | AKAOQ | Achaogen INC | — | NEW | New buy |
| 46 | ✓ | Intec Pharma LTD Jerusalem | — | EXIT | Sold out |
| 47 | ✓ | Tenax Therapeutics INC | — | EXIT | Sold out |
| 48 | ✓ | Portola Pharmaceuticals INC | — | EXIT | Sold out |
| 49 | OCUL | Ocular Therapeutix INC | — | NEW | New buy |
| 50 | AMAG | Amag Pharmaceuticals INC | — | EXIT | Sold out |