CIK: 0001389933
Total reported value
$439.6M
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | ATRC | Atricure INC | Stock-Other | 10.61% | -1.61% | -11.06% | |
| 2 | ABBV | Abbvie INC | Stock-Healthcare | 6.29% | — | — | |
| 3 | ✓ | Nxstage Medical INC | Stock-Other | 5.74% | — | — | |
| 4 | ✓ | Zs Pharma INC | Stock-Other | 4.31% | — | -1.35% | |
| 5 | ACHNEUR | Achillion Pharmaceuticals | Stock-Other | 3.29% | — | — | |
| 6 | BCRX | Biocryst Pharmaceuticals INC | Stock-Other | 2.93% | +0.17% | +16.69% | |
| 7 | AERIEUR | Aerie Pharmaceuticals INC | Stock-Other | 2.92% | — | +5.63% | |
| 8 | BEATEUR | Biotelemetry INC | Stock-Other | 2.86% | — | — | |
| 9 | PODD | Insulet CORP | Stock-Healthcare | 2.73% | — | — | |
| 10 | RIGLUSD | Rigel Pharmaceuticals INC | Stock-Other | 2.72% | — | — | |
| 11 | PLX 4.5 09-15-18 | Protalix Biotherapeautic | Stock-Other | 2.68% | — | — | |
| 12 | ✓ | Discovery Laboratories INC N | Stock-Other | 2.24% | — | +56.60% | |
| 13 | PODD 2 06-15-19 | Insulet Corporation | Stock-Healthcare | 2.21% | — | — | |
| 14 | 2GT | Applied Genetic Technologies | Stock-Other | 2.05% | — | — | |
| 15 | OTICEUR | Otonomy INC | Stock-Other | 1.97% | — | — | |
| 16 | MASI* | Masimo CORP | Stock-Other | 1.76% | — | — | |
| 17 | ✓ | Derma Sciences INC | Stock-Other | 1.67% | — | -4.55% | |
| 18 | ✓ | Xenoport INC | Stock-Other | 1.62% | — | -11.38% | |
| 19 | ✓ | Synergy Pharmaceuticals Inc. | Stock-Other | 1.56% | — | -6.61% | |
| 20 | ✓ | Essa Pharma INC | Stock-Other | 1.41% | — | -1.17% | |
| 21 | PLX1EUR | Protalix Biotherapeutics INC | Stock-Other | 1.40% | — | -3.06% | |
| 22 | ✓ | Cytrx CORP | Stock-Other | 1.37% | — | +93.81% | |
| 23 | CARAEUR | Cara Therapeutics INC | Stock-Other | 1.33% | — | -26.29% | |
| 24 | NEOS | Neos Therapeutics INC | Stock-Other | 1.32% | — | — | |
| 25 | STXS | Stereotaxis INC | Stock-Other | 1.26% | -1.58% | — | |
| 26 | ✓ | Celyad SA | Stock-Other | 1.25% | — | — | |
| 27 | AVAZ | 2x Avalanche ETF | ETF-Other | 1.15% | — | — | |
| 28 | ✓ | Scynexis INC Com New | Stock-Other | 1.13% | — | -2.77% | |
| 29 | ✓ | Novadaq Technologies INC Common | Stock-Other | 1.05% | — | — | |
| 30 | DRNAUSD | Dicerna Pharmaceuticals INC | Stock-Other | 1.01% | — | +42.28% | |
| 31 | GMED 2.75 07-01-17 | Nuvasive INC | Stock-Healthcare | 0.95% | — | — | |
| 32 | ASND | Ascendis Pharma A/S | Stock-Other | 0.93% | -0.19% | -43.08% | |
| 33 | ✓ | Spectranetics CORP | Stock-Other | 0.93% | — | +100.47% | |
| 34 | ZGNXEUR | Zogenix INC | Stock-Other | 0.92% | — | -91.93% | |
| 35 | JNJ | Johnson & Johnson | Stock-Healthcare | 0.87% | — | — | |
| 36 | ✓ | Vitae Pharmaceuticals INC | Stock-Other | 0.77% | — | — | |
| 37 | ✓ | Intec Pharma LTD Jerusalem | Stock-Other | 0.75% | — | — | |
| 38 | ABEO1EUR | Abeona Therapeutics INC | Stock-Other | 0.73% | — | — | |
| 39 | ✓ | Arena Pharmeceuticals INC | Stock-Other | 0.72% | — | +101.90% | |
| 40 | QURE | uniQure N.V. | Stock-Other | 0.71% | — | -12.50% | |
| 41 | CTH | Cynapsus Therapeutics INC | Stock-Other | 0.70% | — | -52.73% | |
| 42 | ✓ | Stock-Other | 0.63% | — | — | ||
| 43 | ✓ | Syneron Medical LTD | Stock-Other | 0.61% | — | -5.50% | |
| 44 | ALDR1EUR | Alder Biopharmaceuticals INC | Stock-Other | 0.59% | — | — | |
| 45 | ✓ | Regulus Therapeutics INC | Stock-Other | 0.58% | — | — | |
| 46 | CDNA | Caredx INC | Stock-Other | 0.56% | — | -6.66% | |
| 47 | CELG | Celgene CORP | Stock-Other | 0.56% | — | — | |
| 48 | GILD | Gilead Sciences INC | Stock-Healthcare | 0.56% | — | — | |
| 49 | ✓ | Exactech INC | Stock-Other | 0.55% | — | — | |
| 50 | ✓ | Ironwood Pharma | Stock-Other | 0.53% | — | +50.00% |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | ✓ | Zs Pharma INC | +1.3% | -1.35% | Trim |
| 2 | ✓ | Nxstage Medical INC | +1.3% | — | Unchanged |
| 3 | BEATEUR | Biotelemetry INC | +1% | — | Unchanged |
| 4 | BCRX | Biocryst Pharmaceuticals INC | +0.1% | +16.69% | Add |
| 5 | 2GT | Applied Genetic Technologies | 0% | — | Unchanged |
| 6 | PLX 4.5 09-15-18 | Protalix Biotherapeautic | 0% | — | Unchanged |
| 7 | PODD | Insulet CORP | -0.1% | — | Unchanged |
| 8 | OTICEUR | Otonomy INC | -0.2% | — | Unchanged |
| 9 | QURE | uniQure N.V. | -0.2% | -12.50% | Trim |
| 10 | ✓ | Syneron Medical LTD | -0.2% | -5.50% | Trim |
| 11 | CDNA | Caredx INC | -0.2% | -6.66% | Trim |
| 12 | ✓ | Cardica INC | -0.3% | -5.60% | Trim |
| 13 | RIGLUSD | Rigel Pharmaceuticals INC | -0.3% | — | Unchanged |
| 14 | ZGNXEUR | Zogenix INC | -0.3% | -91.93% | Trim |
| 15 | ACHNEUR | Achillion Pharmaceuticals | -0.3% | — | Unchanged |
| 16 | DERMEUR | Dermira INC | -0.3% | -60.34% | Trim |
| 17 | ABBV | Abbvie INC | -0.3% | — | Unchanged |
| 18 | ✓ | -0.3% | — | Unchanged | |
| 19 | STXS | Stereotaxis INC | -0.4% | — | Unchanged |
| 20 | ASND | Ascendis Pharma A/S | -0.5% | -43.08% | Trim |
| 21 | ✓ | Discovery Laboratories INC N | -0.5% | +56.60% | Add |
| 22 | ✓ | Derma Sciences INC | -0.6% | -4.55% | Trim |
| 23 | PLX1EUR | Protalix Biotherapeutics INC | -0.6% | -3.06% | Trim |
| 24 | ✓ | Synergy Pharmaceuticals Inc. | -0.7% | -6.61% | Trim |
| 25 | CTH | Cynapsus Therapeutics INC | -0.8% | -52.73% | Trim |
| 26 | ✓ | Essa Pharma INC | -0.8% | -1.17% | Trim |
| 27 | ATRC | Atricure INC | -0.8% | -11.06% | Trim |
| 28 | ✓ | Xenoport INC | -1.1% | -11.38% | Trim |
| 29 | CLVSEUR | Clovis Oncology INC | — | EXIT | Sold out |
| 30 | ✓ | Neothetics INC | — | EXIT | Sold out |
| 31 | NEOS | Neos Therapeutics INC | — | NEW | New buy |
| 32 | ✓ | Targacept INC | — | EXIT | Sold out |
| 33 | AVAZ | 2x Avalanche ETF | — | NEW | New buy |
| 34 | ✓ | Vitae Pharmaceuticals INC | — | NEW | New buy |
| 35 | ✓ | Intec Pharma LTD Jerusalem | — | NEW | New buy |
| 36 | ABEO1EUR | Abeona Therapeutics INC | — | NEW | New buy |
| 37 | ✓ | Arca Biopharma INC | — | EXIT | Sold out |
| 38 | ✓ | — | NEW | New buy | |
| 39 | ALDR1EUR | Alder Biopharmaceuticals INC | — | NEW | New buy |
| 40 | ✓ | Regulus Therapeutics INC | — | NEW | New buy |
| 41 | ECIA | Encision INC | — | EXIT | Sold out |
| 42 | CELG | Celgene CORP | — | NEW | New buy |
| 43 | GILD | Gilead Sciences INC | — | NEW | New buy |
| 44 | RTIXEUR | Rti Surgical Hds INC | — | EXIT | Sold out |
| 45 | CBIO 0 02-19-18 | Catalyst Biosciences | — | NEW | New buy |
| 46 | MGNX | Macrogenics INC | — | NEW | New buy |
| 47 | AMGN | Amgen INC | — | NEW | New buy |
| 48 | VTVTEUR | Vtv Therapeutics Inc- Cl A | — | NEW | New buy |
| 49 | ✓ | Tobira Therapeutics Inc | — | NEW | New buy |
| 50 | AFRM | Affirm Holdings, Inc. | — | EXIT | Sold out |