CIK: 0001053906
Total reported value
$1.0B
| # | Ticker | Issuer | Asset Subclass | Weight | Weight Change | Shares Change | 4Q Trend |
|---|---|---|---|---|---|---|---|
| 1 | WW6 | Ww International INC | Stock-Other | 7.76% | — | — | |
| 2 | SEER | Seer INC | Stock-Other | 7.04% | — | — | |
| 3 | ONC | Beone Medicines Ltd-adr | Stock-Other | 5.55% | — | +11.11% | |
| 4 | LXRX | Lexicon Pharmaceuticals INC | Stock-Other | 5.23% | +1.98% | +18.16% | |
| 5 | XLRN | Acceleron Pharma INC | Stock-Other | 3.85% | — | — | |
| 6 | ALNY | Alnylam Pharmaceuticals INC | Stock-Healthcare | 2.79% | — | +25.00% | |
| 7 | FATE | Fate Therapeutics INC | Stock-Other | 2.73% | — | -6.67% | |
| 8 | MRTXEUR | Mirati Therapeutics INC | Stock-Other | 2.36% | — | — | |
| 9 | 1K0 | Igm Biosciences INC | Stock-Other | 2.27% | — | +74.19% | |
| 10 | SRRK | Scholar Rock Holding CORP | Stock-Other | 2.19% | — | -15.84% | |
| 11 | GDS | Gds Holdings LTD - Adr | Stock-Other | 2.01% | — | — | |
| 12 | BABA | Alibaba Group Holding-sp Adr | Stock-Consumer Disc | 2.00% | — | -5.88% | |
| 13 | ✓ | Stock-Other | 1.92% | — | — | ||
| 14 | ARGX | Argenx Se - Adr | Stock-Healthcare | 1.89% | — | -7.46% | |
| 15 | ABBV | Abbvie INC | Stock-Healthcare | 1.84% | — | +60.00% | |
| 16 | BNTX | Biontech Se-adr | Stock-Other | 1.75% | — | -42.24% | |
| 17 | AM6 | Amicus Therapeutics INC | Stock-Other | 1.73% | — | -12.50% | |
| 18 | GBIOGBX | Generation Bio Co | Stock-Other | 1.71% | — | — | |
| 19 | TGTX | Tg Therapeutics INC | Stock-Healthcare | 1.68% | — | — | |
| 20 | Z | Zillow Group INC - C | Stock-Comm Services | 1.53% | — | +175.00% | |
| 21 | SDGR | Schrodinger INC | Stock-Other | 1.36% | — | -11.14% | |
| 22 | BMY | Bristol-myers Squibb Co | Stock-Healthcare | 1.33% | — | — | |
| 23 | BEKE | Ke Holdings Inc-adr | Stock-Other | 1.32% | — | +14.94% | |
| 24 | MORFUSD | Morphic Holding INC | Stock-Other | 1.19% | — | — | |
| 25 | ATRAGBX | Atara Biotherapeutics INC | Stock-Other | 1.18% | — | +24.44% | |
| 26 | BDTX | Black Diamond Therapeutics I | Stock-Other | 1.13% | — | +8.22% | |
| 27 | SQZB | Sqz Biotechnologies Co | Stock-Other | 1.00% | — | — | |
| 28 | TPB | Turning Point Brands, Inc. | Stock-Other | 0.92% | — | +7.69% | |
| 29 | PRAX | Praxis Precision Medicines, Inc. | Stock-Other | 0.89% | — | — | |
| 30 | CCXIEUR | Chemocentryx INC | Stock-Other | 0.86% | — | — | |
| 31 | KRON1USD | Kronos Bio INC | Stock-Other | 0.85% | — | — | |
| 32 | CERE1EUR | Cerevel Therapeutics Holding | Stock-Other | 0.81% | — | — | |
| 33 | 2662247D | Iteos Therapeutics INC | Stock-Other | 0.79% | — | — | |
| 34 | FHTX | Foghorn Therapeutics INC | Stock-Other | 0.75% | — | — | |
| 35 | SG7 | Sage Therapeutics INC | Stock-Other | 0.74% | — | +79.94% | |
| 36 | NBP | Novabridge Biosciences | Stock-Other | 0.73% | — | — | |
| 37 | DNLI | Denali Therapeutics INC | Stock-Other | 0.72% | — | — | |
| 38 | SWTXUSD | Springworks Therapeutics INC | Stock-Other | 0.70% | — | +57.89% | |
| 39 | ✓ | Mersana Therapeutics INC | Stock-Other | 0.69% | — | +20.00% | |
| 40 | TREUR | Trillium Therapeutics INC | Stock-Other | 0.66% | — | +40.00% | |
| 41 | RUBYUSD | Rubius Therapeutics INC | Stock-Other | 0.62% | — | — | |
| 42 | DCPHEUR | Deciphera Pharmaceuticals In | Stock-Other | 0.61% | — | -16.67% | |
| 43 | TSHA | Taysha Gene Therapies INC | Stock-Other | 0.59% | — | -8.77% | |
| 44 | ADVMCHF | Adverum Biotechnologies INC | Stock-Other | 0.58% | — | +38.89% | |
| 45 | REPL | Replimune Group INC | Stock-Other | 0.57% | — | — | |
| 46 | BDQM | Albireo Pharma INC | Stock-Other | 0.56% | — | -17.78% | |
| 47 | ALXO | Alx Oncology Holdings INC | Stock-Other | 0.56% | — | +200.00% | |
| 48 | QURE | uniQure N.V. | Stock-Other | 0.54% | — | -6.67% | |
| 49 | NG | Novagold Resources INC | Stock-Other | 0.54% | — | — | |
| 50 | GOSS | Gossamer Bio INC | Stock-Other | 0.49% | — | — |
| # | Ticker | Issuer | Weight Change | Shares Change | Action |
|---|---|---|---|---|---|
| 1 | LXRX | Lexicon Pharmaceuticals INC | +3.1% | +18.16% | Add |
| 2 | FATE | Fate Therapeutics INC | +1.3% | -6.67% | Trim |
| 3 | SRRK | Scholar Rock Holding CORP | +1.1% | -15.84% | Trim |
| 4 | 1K0 | Igm Biosciences INC | +1% | +74.19% | Add |
| 5 | Z | Zillow Group INC - C | +1% | +175.00% | Add |
| 6 | WW6 | Ww International INC | +1% | — | Unchanged |
| 7 | ABBV | Abbvie INC | +0.8% | +60.00% | Add |
| 8 | TGTX | Tg Therapeutics INC | +0.7% | — | Unchanged |
| 9 | ATRAGBX | Atara Biotherapeutics INC | +0.5% | +24.44% | Add |
| 10 | ALXO | Alx Oncology Holdings INC | +0.5% | +200.00% | Add |
| 11 | SG7 | Sage Therapeutics INC | +0.4% | +79.94% | Add |
| 12 | ✓ | +0.4% | — | Unchanged | |
| 13 | DNLI | Denali Therapeutics INC | +0.4% | — | Unchanged |
| 14 | SWTXUSD | Springworks Therapeutics INC | +0.4% | +57.89% | Add |
| 15 | AM6 | Amicus Therapeutics INC | +0.4% | -12.50% | Trim |
| 16 | MRTXEUR | Mirati Therapeutics INC | +0.3% | — | Unchanged |
| 17 | SDGR | Schrodinger INC | +0.3% | -11.14% | Trim |
| 18 | BLU | Bellus Health INC | +0.3% | +900.00% | Add |
| 19 | CRISEUR | Curis INC | +0.3% | +28.48% | Add |
| 20 | ✓ | Mersana Therapeutics INC | +0.2% | +20.00% | Add |
| 21 | TPB | Turning Point Brands, Inc. | +0.2% | +7.69% | Add |
| 22 | XLRN | Acceleron Pharma INC | 0% | — | Unchanged |
| 23 | ALNY | Alnylam Pharmaceuticals INC | 0% | +25.00% | Add |
| 24 | MRNA | Moderna INC | -0.4% | -83.33% | Trim |
| 25 | BABA | Alibaba Group Holding-sp Adr | -1% | -5.88% | Trim |
| 26 | BNTX | Biontech Se-adr | -1.2% | -42.24% | Trim |
| 27 | QQQ | Invesco Qqq Trust Series 1 | — | EXIT | Sold out |
| 28 | SEER | Seer INC | — | NEW | New buy |
| 29 | GS | Goldman Sachs Group INC | — | EXIT | Sold out |
| 30 | JPM | Jpmorgan Chase & Co | — | EXIT | Sold out |
| 31 | BMY | Bristol-myers Squibb Co | — | NEW | New buy |
| 32 | BAC | Bank Of America CORP | — | EXIT | Sold out |
| 33 | SQZB | Sqz Biotechnologies Co | — | NEW | New buy |
| 34 | PRAX | Praxis Precision Medicines, Inc. | — | NEW | New buy |
| 35 | CCXIEUR | Chemocentryx INC | — | NEW | New buy |
| 36 | KRON1USD | Kronos Bio INC | — | NEW | New buy |
| 37 | XLI | Ss Industrial Select Sector | — | EXIT | Sold out |
| 38 | CERE1EUR | Cerevel Therapeutics Holding | — | NEW | New buy |
| 39 | FHTX | Foghorn Therapeutics INC | — | NEW | New buy |
| 40 | MS | Morgan Stanley | — | EXIT | Sold out |
| 41 | AAPL | Apple INC | — | EXIT | Sold out |
| 42 | SLB | Slb LTD | — | NEW | New buy |
| 43 | C | Citigroup INC | — | EXIT | Sold out |
| 44 | STNE | StoneCo Ltd. | — | EXIT | Sold out |
| 45 | ✓ | Forma Therapeutics Holdings | — | NEW | New buy |
| 46 | ZYMEUSD | Zymeworks INC | — | NEW | New buy |
| 47 | NBTX | Nanobiotix SA - Adr | — | NEW | New buy |
| 48 | IQ | Iqiyi Inc-adr | — | NEW | New buy |
| 49 | GM | General Motors Co | — | EXIT | Sold out |
| 50 | ✓ | Sigilon Therapeutics INC | — | NEW | New buy |