NC

NEXTBio Capital Management LP

Momentum followerQuality / disciplined sizing

Total reported value

$215.4M

Reporting period: 2026-03-31 · Number of holdings: 24

NEXTBio Capital Management LP disclosed 24 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $215.4M and a quarterly turnover rate of 32.0%.

Personality snowflake

Concentration
27.97
Portfolio Stability
32.01
Momentum/Contrarian
100
Sector conviction
0
Diversification
48
Sizing Uniformity
91.59

Recent moves

  • Trim ZBIO

    +32.5%　-$3.3M

  • Trim VSTM

    -0.0%　-$3.2M

  • Add STTK

    0.0%　$8.8M

  • Add CMPS

    +168.6%　$6.0M

  • Add 430

    +9.7%　$9.6M

  • Trim CMPX

    -23.9%　-$1.5M

Holdings Map

New buyAddUnchangedTrim

Top 10 holdings by weight

Full holdings list this quarter

#TickerIssuerAsset SubclassWeightWeight ChangeShares Change4Q Trend
1430Terns Pharmaceuticals INCStock-Other14.80%+1.74%+9.68%
2PTGXProtagonist Therapeutics INCStock-Other11.24%-0.52%—
3STTKShattuck Labs INCStock-Other9.40%+2.66%—
4VORVor Biopharma INCStock-Other8.28%+0.61%—
5CMPSCompass Pathways PLCStock-Other5.19%+2.14%+168.58%
6RYTMRhythm Pharmaceuticals INCStock-Other5.09%+0.85%+86.54%
7XENEXenon Pharmaceuticals INCStock-Other4.95%+0.12%-0.26%
8PVLAPalvella Therapeutics INCStock-Other4.79%-0.29%—
9ZBIOZenas Biopharma INCStock-Other3.87%-2.99%+32.53%
10IVAInventiva SA - AdrStock-Other3.44%-0.10%+2.68%
11VSTMVerastem INCStock-Other3.22%-2.70%-0.04%
12✓ Crescent Biopharma INC.Stock-Other3.18%+0.59%—
13ORICOric Pharmaceuticals INCStock-Other3.08%+0.13%-14.96%
14GPCRStructure Therapeutics INCStock-Other2.98%-0.87%+41.08%
15PCVXVaxcyte INCStock-Other2.57%-0.01%-0.27%
16COGTCogent Biosciences INCStock-Other2.34%+0.34%+36.91%
17CMPXCompass Therapeutics INCStock-Other2.08%-1.43%-23.86%
18EVMNEvommune INCStock-Other1.96%-0.33%-19.37%
19OCSOculis Holding AGStock-Other1.85%+0.10%-0.11%
20ZLABZai Lab Ltd-adrStock-Other1.60%-0.09%+12.24%
21IRONDisc Medicine INCStock-Other1.56%-0.43%+23.09%
224XC1Kalvista Pharmaceuticals INCStock-Other1.23%-0.02%—
23SMMTSummit Therapeutics INCStock-Other0.79%+0.79%NEW
24ACETAdicet Bio INCStock-Other0.50%-0.28%—

Holding changes this quarter

NEXTBio Capital Management LP's most significant position changes for 2026-03-31: New buy: Summit Therapeutics INC (SMMT); Add: Zenas Biopharma INC (ZBIO) — shares +32.53%; Trim: Verastem INC (VSTM) — shares -0.04%; Add: Compass Pathways PLC (CMPS) — shares +168.58%; Add: Terns Pharmaceuticals INC (430) — shares +9.68%.

Position changes disclosed by NEXTBio Capital Management LP for the quarter ending 2026-03-31, including ticker, issuer, weight change, shares change, and action
#TickerIssuerWeight ChangeShares ChangeAction
1STTKShattuck Labs INC+2.7%—Unchanged
2CMPSCompass Pathways PLC+2.1%+168.58%Add
3430Terns Pharmaceuticals INC+1.7%+9.68%Add
4RYTMRhythm Pharmaceuticals INC+0.9%+86.54%Add
5VORVor Biopharma INC+0.6%—Unchanged
6✓ Crescent Biopharma INC.+0.6%—Unchanged
7COGTCogent Biosciences INC+0.3%+36.91%Add
8ORICOric Pharmaceuticals INC+0.1%-14.96%Trim
9XENEXenon Pharmaceuticals INC+0.1%-0.26%Trim
10OCSOculis Holding AG+0.1%-0.11%Trim
11PCVXVaxcyte INC0%-0.27%Trim
124XC1Kalvista Pharmaceuticals INC0%—Unchanged
13ZLABZai Lab Ltd-adr-0.1%+12.24%Add
14IVAInventiva SA - Adr-0.1%+2.68%Add
15ACETAdicet Bio INC-0.3%—Unchanged
16PVLAPalvella Therapeutics INC-0.3%—Unchanged
17EVMNEvommune INC-0.3%-19.37%Trim
18IRONDisc Medicine INC-0.4%+23.09%Add
19PTGXProtagonist Therapeutics INC-0.5%—Unchanged
20GPCRStructure Therapeutics INC-0.9%+41.08%Add
21CMPXCompass Therapeutics INC-1.4%-23.86%Trim
22VSTMVerastem INC-2.7%-0.04%Trim
23ZBIOZenas Biopharma INC-3%+32.53%Add
24SMMTSummit Therapeutics INC—NEWNew buy

FAQ

What is NEXTBio Capital Management LP and what type of investor is it?
NEXTBio Capital Management LP is a investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-03-31), the firm manages a tracked equity portfolio valued at approximately $215.4M, spread across 24 disclosed positions.
What are NEXTBio Capital Management LP's largest equity positions?
Based on the latest 13F filing, NEXTBio Capital Management LP's top holdings by market value are: 1. Terns Pharmaceuticals INC (430) — $31.9M (14.8%) 2. Protagonist Therapeutics INC (PTGX) — $24.2M (11.2%) 3. Shattuck Labs INC (STTK) — $20.3M (9.4%) 4. Vor Biopharma INC (VOR) — $17.8M (8.3%) 5. Compass Pathways PLC (CMPS) — $11.2M (5.2%)
What changes did NEXTBio Capital Management LP make in its most recent portfolio filing?
In the latest reported quarter, NEXTBio Capital Management LP made 17 notable position adjustments: 1 new positions were initiated, 9 existing holdings were added to, 7 positions were partially reduced, and 0 were completely exited. The largest of these moves: New buy: Summit Therapeutics INC (SMMT); Add: Zenas Biopharma INC (ZBIO) — shares +32.53%; Trim: Verastem INC (VSTM) — shares -0.04%; Add: Compass Pathways PLC (CMPS) — shares +168.58%; Add: Terns Pharmaceuticals INC (430) — shares +9.68%
What sectors does NEXTBio Capital Management LP focus on?
Sector breakdown data is not yet available for NEXTBio Capital Management LP. Check back after the next 13F processing cycle.