Blue Water Life Science Advisors, LP

Sector-focusedContrarianQuality / disciplined sizing

Total reported value

$124.7M

Reporting period: 2026-03-31 · Number of holdings: 10

Blue Water Life Science Advisors, LP disclosed 10 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $124.7M and a quarterly turnover rate of 72.6%.

Personality snowflake

Concentration: 50.71
Portfolio Stability: 72.65
Momentum/Contrarian: 0
Sector conviction: 100
Diversification: 20
Sizing Uniformity: 94.54

Recent moves

Trim NTRA
-68.3%　-$23.5M
Add CDNA
+83.3%　$6.6M
Trim ADPT
-42.8%　-$14.6M
Trim GH
-31.8%　-$13.9M
Add TWST
-27.9%　$966.8K
Add TEM
+81.0%　$2.0M

Holdings Map

New buyAddUnchangedTrim

Top 10 holdings by weight

Full holdings list this quarter

#	Ticker	Issuer	Asset Subclass	Weight	Weight Change	Shares Change
1	TXG	10x Genomics Inc-class A	Stock-Other	18.56%	+18.56%	NEW
2	GH	Guardant Health INC	Stock-Healthcare	17.94%	-4.82%	-31.77%
3	CDNA	Caredx INC	Stock-Other	13.02%	+6.99%	+83.33%
4	ADPT	Adaptive Biotechnologies	Stock-Other	11.24%	-6.75%	-42.77%
5	TWST	Twist Bioscience CORP	Stock-Other	10.52%	+2.90%	-27.94%
6	PSNL	Personalis INC	Stock-Other	8.56%	+0.19%	—
7	NTRA	Natera INC	Stock-Healthcare	7.18%	-13.16%	-68.34%
8	QTRX	Quanterix CORP	Stock-Other	6.05%	-2.30%	+2.39%
9	TEM	Tempus Ai Inc-cl A	Stock-Healthcare	5.67%	+2.47%	+81.01%
10	BLLN	Billiontoone INC Cl A	Stock-Other	1.27%	+1.27%	NEW

Reported value over time

Sector allocation

Sector allocation over time

Quarterly history

Period	Holdings	Total value	Stability	Top holdings
2026-03-31	10	$124.7M	73	1TXG 2GH 3CDNA Top holdings2026-03-31 1.TXG 2.GH 3.CDNA 4.ADPT 5.TWST 6.PSNL 7.NTRA 8.QTRX 9.TEM 10.BLLN
2025-12-31	9	$159.3M	43	1GH 2NTRA 3ADPT Top holdings2025-12-31 1.GH 2.NTRA 3.ADPT 4.PSNL 5.QTRX 6.TWST 7.CDNA 8.GRAL 9.TEM
2025-09-30	7	$109.6M	46	1ADPT 2GH 3NTRA Top holdings2025-09-30 1.ADPT 2.GH 3.NTRA 4.PSNL 5.CDNA 6.TEM 7.QTRX
2025-06-30	8	$126.3M	0	1NTRA 2ADPT 3GH Top holdings2025-06-30 1.NTRA 2.ADPT 3.GH 4.CDNA 5.TXG 6.PSNL 7.QTRX 8.00974H
2025-03-31	7	$100.9M	100	1GH 2NTRA 3ADPT Top holdings2025-03-31 1.GH 2.NTRA 3.ADPT 4.CDNA 5.00974H 6.PSNL 7.QTRX
2024-12-31	9	$112.9M	0	1NTRA 2GH 3CDNA Top holdings2024-12-31 1.NTRA 2.GH 3.CDNA 4.ADPT 5.00974H 6.PSNL 7.EXK 8.TEM 9.QTRX
2024-09-30	8	$113.7M	0	1NTRA 2CDNA 3EXK Top holdings2024-09-30 1.NTRA 2.CDNA 3.EXK 4.00974H 5.ADPT 6.GH 7.PSNL 8.QTRX
2024-06-30	8	$102.8M	0	1NTRA 2GH300974H Top holdings2024-06-30 1.NTRA 2.GH 3.00974H 4.CDNA 5.TXG 6.QTRX 7.EXK 8.MXCT
2024-03-31	8	$106.3M	0	1NTRA200974H3GH Top holdings2024-03-31 1.NTRA 2.00974H 3.GH 4.TXG 5.QTRX 6.ADPT 7.EXK 8.MXCT
2023-12-31	9	$114.2M	0	1NTRA200974H3GH Top holdings2023-12-31 1.NTRA 2.00974H 3.GH 4.TMO 5.TXG 6.MXCT 7.ADPT 8.QTRX 9.NSTGEUR
2023-09-30	7	$105.9M	0	1NTRA200974H3GH Top holdings2023-09-30 1.NTRA 2.00974H 3.GH 4.ADPT 5.NSTGEUR 6.MXCT 7.835431
2023-06-30	7	$148.2M	0	1NTRA200974H3GH Top holdings2023-06-30 1.NTRA 2.00974H 3.GH 4.ADPT 5.NSTGEUR 6.MXCT 7.835431
2023-03-31	8	$151.2M	0	1NTRA 2ADPT300974H Top holdings2023-03-31 1.NTRA 2.ADPT 3.00974H 4.MXCT 5.GH 6.BRKR 7.CTKB 8.835431
2022-12-31	8	$148.9M	0	1NTRA 2GH 3ADPT Top holdings2022-12-31 1.NTRA 2.GH 3.ADPT 4.00974H 5.MXCT 6.CTKB 7.835431 8.DHR
2022-09-30	9	$247.8M	0	1GH 2NTRA 3CTKB Top holdings2022-09-30 1.GH 2.NTRA 3.CTKB 4.TWST 5.ADPT 6.00974H 7.MXCT 8.TECH 9.SLGCUSD
2022-06-30	9	$184.1M	0	1GH 2NTRA300974H Top holdings2022-06-30 1.GH 2.NTRA 3.00974H 4.ADPT 5.CTKB 6.BRKR 7.TECH 8.CDNA 9.SLGCUSD
2022-03-31	10	$210.7M	0	1NTRA 2GH 3CDNA Top holdings2022-03-31 1.NTRA 2.GH 3.CDNA 4.PACB 5.00974H 6.TXG 7.SLGCUSD 8.DNA4EUR 9.OLN 10.704723
2021-12-31	13	$326.9M	0	1NTRA 2TMO 3GH Top holdings2021-12-31 1.NTRA 2.TMO 3.GH 4.CDNA 5.TECH 6.A 7.00974H 8.AVTR 9.DNA4EUR 10.DHR
2021-09-30	24	$307.4M	0	1NTRA 2CDNA 3TMO Top holdings2021-09-30 1.NTRA 2.CDNA 3.TMO 4.TECH 5.A 6.RVTY 7.DNA4EUR 8.GH 9.TWST 10.NEO
2021-06-30	22	$265.8M	87	1NTRA 2CDNA 3AMRSEUR Top holdings2021-06-30 1.NTRA 2.CDNA 3.AMRSEUR 4.TMO 5.NEO 6.GH 7.ILMN 8.TECH 9.40434H 10.GOOGL
2021-03-31	24	$204.7M	49	1AMRSEUR 2CDNA 3NTRA Top holdings2021-03-31 1.AMRSEUR 2.CDNA 3.NTRA 4.GH 5.EXK 6.ILMN 7.ADPT 8.TMO 9.BLIUSD 10.A
2020-12-31	21	$170.4M	0	1CDNA 2NTRA 3GH Top holdings2020-12-31 1.CDNA 2.NTRA 3.GH 4.BLIUSD 5.AMRSEUR 6.ADPT 7.ILMN 8.TWST 9.EXK 10.GNMK

Holding changes this quarter

Blue Water Life Science Advisors, LP's most significant position changes for 2026-03-31: New buy: 10x Genomics Inc-class A (TXG); Sold out: Grail INC (GRAL); New buy: Billiontoone INC Cl A (BLLN); Trim: Natera INC (NTRA) — shares -68.34%; Add: Caredx INC (CDNA) — shares +83.33%.

Position changes disclosed by Blue Water Life Science Advisors, LP for the quarter ending 2026-03-31, including ticker, issuer, weight change, shares change, and action
#	Ticker	Issuer	Weight Change	Shares Change	Action
1	CDNA	Caredx INC	+7%	+83.33%	Add
2	TWST	Twist Bioscience CORP	+2.9%	-27.94%	Trim
3	TEM	Tempus Ai Inc-cl A	+2.5%	+81.01%	Add
4	PSNL	Personalis INC	+0.2%	—	Unchanged
5	QTRX	Quanterix CORP	-2.3%	+2.39%	Add
6	GH	Guardant Health INC	-4.8%	-31.77%	Trim
7	ADPT	Adaptive Biotechnologies	-6.8%	-42.77%	Trim
8	NTRA	Natera INC	-13.2%	-68.34%	Trim
9	TXG	10x Genomics Inc-class A	—	NEW	New buy
10	GRAL	Grail INC	—	EXIT	Sold out
11	BLLN	Billiontoone INC Cl A	—	NEW	New buy

FAQ

What is Blue Water Life Science Advisors, LP and what type of investor is it?

Blue Water Life Science Advisors, LP is a investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-03-31), the firm manages a tracked equity portfolio valued at approximately $124.7M, spread across 10 disclosed positions.

What are Blue Water Life Science Advisors, LP's largest equity positions?

Based on the latest 13F filing, Blue Water Life Science Advisors, LP's top holdings by market value are: 1. 10x Genomics Inc-class A (TXG) — $23.1M (18.6%) 2. Guardant Health INC (GH) — $22.4M (17.9%) 3. Caredx INC (CDNA) — $16.2M (13.0%) 4. Adaptive Biotechnologies (ADPT) — $14.0M (11.2%) 5. Twist Bioscience CORP (TWST) — $13.1M (10.5%)

What changes did Blue Water Life Science Advisors, LP make in its most recent portfolio filing?

In the latest reported quarter, Blue Water Life Science Advisors, LP made 10 notable position adjustments: 2 new positions were initiated, 3 existing holdings were added to, 4 positions were partially reduced, and 1 were completely exited. The largest of these moves: New buy: 10x Genomics Inc-class A (TXG); Sold out: Grail INC (GRAL); New buy: Billiontoone INC Cl A (BLLN); Trim: Natera INC (NTRA) — shares -68.34%; Add: Caredx INC (CDNA) — shares +83.33%

What sectors does Blue Water Life Science Advisors, LP focus on?

Blue Water Life Science Advisors, LP is concentrated in the following sectors based on its current disclosed equity portfolio: • Health Care: 100.0%