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Omega Fund Management, LLC

Momentum followerQuality / disciplined sizingConcentrated strategy

Total reported value

$163.1M

Reporting period: 2026-03-31 · Number of holdings: 10

Omega Fund Management, LLC disclosed 10 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $163.1M and a quarterly turnover rate of 64.2%.

Personality snowflake

Concentration
75.14
Portfolio Stability
64.19
Momentum/Contrarian
100
Sector conviction
0
Diversification
20
Sizing Uniformity
90.12

Recent moves

  • Add BCAX

    +8.5%　$10.5M

  • Trim BBNX

    0.0%　-$26.9M

  • Trim NUVB

    0.0%　-$37.7M

  • Add BBOT

    0.0%　-$11.7M

  • Add ALMS

    -63.1%　-$1.1M

  • Add 29286M105

    0.0%　-$1.9M

Holdings Map

New buyAddUnchangedTrim

Top 10 holdings by weight

Full holdings list this quarter

#TickerIssuerAsset SubclassWeightWeight ChangeShares Change4Q Trend
1BCAXBicara Therapeutics INCStock-Other29.16%+16.21%+8.50%
2NUVBNuvation Bio INCStock-Other21.25%-4.02%—
3BBOTBridgebio Oncology TherapeutStock-Other18.05%+3.68%—
4KMTSKestra Medical Technologies, Ltd.Stock-Other12.49%-0.22%-25.59%
5BBNXBeta Bionics INCStock-Other8.08%-5.92%—
6✓ Engene Holdings INCStock-Other3.66%+0.90%—
7ALMSAlumis INCStock-Other3.26%+1.03%-63.07%
8SANASana Biotechnology INCStock-Other1.49%+0.29%—
9IMAImagenebio INCStock-Other1.40%+0.30%—
10REPLReplimune Group INCStock-Other1.17%+0.33%—

Holding changes this quarter

Omega Fund Management, LLC's most significant position changes for 2026-03-31: Sold out: Upstream Bio INC (UPB); Add: Bicara Therapeutics INC (BCAX) — shares +8.50%; Trim: Alumis INC (ALMS) — shares -63.07%; Trim: Kestra Medical Technologies, Ltd. (KMTS) — shares -25.59%.

Position changes disclosed by Omega Fund Management, LLC for the quarter ending 2026-03-31, including ticker, issuer, weight change, shares change, and action
#TickerIssuerWeight ChangeShares ChangeAction
1BCAXBicara Therapeutics INC+16.2%+8.50%Add
2BBOTBridgebio Oncology Therapeut+3.7%—Unchanged
3ALMSAlumis INC+1%-63.07%Trim
4✓ Engene Holdings INC+0.9%—Unchanged
5REPLReplimune Group INC+0.3%—Unchanged
6IMAImagenebio INC+0.3%—Unchanged
7SANASana Biotechnology INC+0.3%—Unchanged
8KMTSKestra Medical Technologies, Ltd.-0.2%-25.59%Trim
9NUVBNuvation Bio INC-4%—Unchanged
10BBNXBeta Bionics INC-5.9%—Unchanged
11UPBUpstream Bio INC—EXITSold out

FAQ

What is Omega Fund Management, LLC and what type of investor is it?
Omega Fund Management, LLC is a investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-03-31), the firm manages a tracked equity portfolio valued at approximately $163.1M, spread across 10 disclosed positions.
What are Omega Fund Management, LLC's largest equity positions?
Based on the latest 13F filing, Omega Fund Management, LLC's top holdings by market value are: 1. Bicara Therapeutics INC (BCAX) — $47.6M (29.2%) 2. Nuvation Bio INC (NUVB) — $34.7M (21.3%) 3. Bridgebio Oncology Therapeut (BBOT) — $29.4M (18.1%) 4. Kestra Medical Technologies, Ltd. (KMTS) — $20.4M (12.5%) 5. Beta Bionics INC (BBNX) — $13.2M (8.1%)
What changes did Omega Fund Management, LLC make in its most recent portfolio filing?
In the latest reported quarter, Omega Fund Management, LLC made 4 notable position adjustments: 0 new positions were initiated, 1 existing holdings were added to, 2 positions were partially reduced, and 1 were completely exited. The largest of these moves: Sold out: Upstream Bio INC (UPB); Add: Bicara Therapeutics INC (BCAX) — shares +8.50%; Trim: Alumis INC (ALMS) — shares -63.07%; Trim: Kestra Medical Technologies, Ltd. (KMTS) — shares -25.59%
What sectors does Omega Fund Management, LLC focus on?
Sector breakdown data is not yet available for Omega Fund Management, LLC. Check back after the next 13F processing cycle.