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Boxer Capital Management, LLC

Sector-focusedMomentum followerHigh-turnover trader

Total reported value

$761.7M

Reporting period: 2026-03-31 · Number of holdings: 54

Boxer Capital Management, LLC disclosed 54 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $761.7M and a quarterly turnover rate of 64.7%.

Personality snowflake

Concentration
43.52
Portfolio Stability
64.74
Momentum/Contrarian
100
Sector conviction
100
Diversification
100
Sizing Uniformity
77.71

Recent moves

  • Add TNGX

    0.0%　$131.2M

  • Trim KYMR

    0.0%　$1.8M

  • Trim CELC

    0.0%　$3.2M

  • Trim PTCT

    0.0%　-$1.6M

  • Add VIR

    +198.6%　$13.0M

  • Trim URGN

    0.0%　-$2.7M

Holdings Map

New buyAddUnchangedTrim

Top 10 holdings by weight

Full holdings list this quarter

#TickerIssuerAsset SubclassWeightWeight ChangeShares Change4Q Trend
1TNGXTango Therapeutics INCStock-Other29.87%+8.78%—
2KODKodiak Sciences INCStock-Other6.81%-0.14%+19.81%
3RVMDRevolution Medicines INCStock-Healthcare6.38%-0.59%+25.00%
4KYMRKymera Therapeutics INCStock-Other3.60%-2.00%—
5CELCCelcuity INCStock-Other3.37%-1.54%—
6SRZNSurrozen INCStock-Other2.93%+0.87%+84.14%
7ABVXAbivax Sa-adrStock-Other2.92%-0.77%+60.00%
8430Terns Pharmaceuticals INCStock-Other2.60%-0.72%—
9PCVXVaxcyte INCStock-Other2.48%+2.48%NEW
10CAPRCapricor Therapeutics INCStock-Other2.35%+0.30%+81.54%
11PTGXProtagonist Therapeutics INCStock-Other2.35%-0.90%—
12VIRVir Biotechnology INCStock-Other2.20%+1.38%+198.56%
13CRVSCorvus Pharmaceuticals INCStock-Other2.11%+2.11%NEW
14PRAXPraxis Precision Medicines IStock-Other1.97%-1.03%—
15PTCTPtc Therapeutics INCStock-Healthcare1.79%-1.54%—
16PGENPrecigen INCStock-Other1.78%+0.52%+154.55%
17DFTXDefinium Therapeutics INCStock-Other1.49%+1.49%NEW
18AMLXAmylyx Pharmaceuticals INCStock-Other1.46%-0.66%—
19QUREuniQure N.V.Stock-Other1.42%-0.10%+128.28%
20IRDOpus Genetics INCStock-Other1.34%+1.34%NEW
21CORTCorcept Therapeutics INCStock-Healthcare1.32%+1.32%NEW
22URGNUroGen Pharma Ltd.Stock-Other1.18%-1.38%—
23REPLReplimune Group INCStock-Other1.18%-0.42%+56.67%
24COGTCogent Biosciences INCStock-Other1.14%-0.61%—
25PALIPalisade Bio INCStock-Other1.10%-1.37%—
26✓ Crescent Biopharma INC.Stock-Other1.09%+1.09%NEW
27SLNOEURSoleno Therapeutics INCStock-Other0.88%+0.88%NEW
28ALLOAllogene Therapeutics INCStock-Other0.87%+0.87%NEW
29CYTKCytokinetics INCStock-Healthcare0.87%-0.52%—
30CTNMContineum Therapeutics Inc-aStock-Other0.85%-0.39%—
31APGEApogee Therapeutics INCStock-Other0.77%-0.39%—
32RLMDRelmada Therapeutics INCStock-Other0.77%+0.77%NEW
33✓ Zura Bio LTDStock-Other0.70%+0.64%+1700.00%
34MLTXMoonlake ImmunotherapeuticsStock-Other0.67%-0.12%—
35AVTXAvalo Therapeutics INCStock-Other0.59%-0.50%+9.09%
36INOInovio Pharmaceuticals INCStock-Other0.54%—-2.07%
37GPCRStructure Therapeutics INCStock-Other0.47%-0.67%—
38SRPTSarepta Therapeutics INCStock-Healthcare0.43%——
39HELPCybin INCStock-Other0.40%-0.88%-10.49%
40OCULOcular Therapeutix INCStock-Other0.39%+0.39%NEW
41ANTXAn2 Therapeutics INCStock-Other0.34%+0.34%NEW
42CLNNClene INCStock-Other0.31%+0.05%+139.07%
43ORICOric Pharmaceuticals INCStock-Other0.29%+0.29%NEW
44SLDBSolid Biosciences INCStock-Other0.28%-0.09%—
45IVVDInvivyd INCStock-Other0.26%-0.55%—
46LBRXLb Pharmaceuticals INCStock-Other0.23%——
47KPTIKaryopharm Therapeutics INCStock-Other0.22%—+19.80%
48NRIXNurix Therapeutics INCStock-Other0.20%-0.22%—
49UPBUpstream Bio INCStock-Other0.18%-0.71%—
50MISTMilestone Pharmaceuticals InStock-Other0.10%-0.19%—
1–50 of 54

Holding changes this quarter

Boxer Capital Management, LLC's most significant position changes for 2026-03-31: New buy: Vaxcyte INC (PCVX); New buy: Corvus Pharmaceuticals INC (CRVS); Sold out: Cidara Therapeutics INC (CDTX); New buy: Definium Therapeutics INC (DFTX); New buy: Opus Genetics INC (IRD).

Position changes disclosed by Boxer Capital Management, LLC for the quarter ending 2026-03-31, including ticker, issuer, weight change, shares change, and action
#TickerIssuerWeight ChangeShares ChangeAction
1TNGXTango Therapeutics INC+8.8%—Unchanged
2VIRVir Biotechnology INC+1.4%+198.56%Add
3SRZNSurrozen INC+0.9%+84.14%Add
4✓ Zura Bio LTD+0.6%+1700.00%Add
5PGENPrecigen INC+0.5%+154.55%Add
6CAPRCapricor Therapeutics INC+0.3%+81.54%Add
7CLNNClene INC+0.1%+139.07%Add
8SLDBSolid Biosciences INC-0.1%—Unchanged
9QUREuniQure N.V.-0.1%+128.28%Add
10MLTXMoonlake Immunotherapeutics-0.1%—Unchanged
11KODKodiak Sciences INC-0.1%+19.81%Add
12MISTMilestone Pharmaceuticals In-0.2%—Unchanged
13NRIXNurix Therapeutics INC-0.2%—Unchanged
14CTNMContineum Therapeutics Inc-a-0.4%—Unchanged
15APGEApogee Therapeutics INC-0.4%—Unchanged
16REPLReplimune Group INC-0.4%+56.67%Add
17PEPGPepgen INC-0.5%-27.01%Trim
18AVTXAvalo Therapeutics INC-0.5%+9.09%Add
19CYTKCytokinetics INC-0.5%—Unchanged
20IVVDInvivyd INC-0.6%—Unchanged
21RVMDRevolution Medicines INC-0.6%+25.00%Add
22COGTCogent Biosciences INC-0.6%—Unchanged
23AMLXAmylyx Pharmaceuticals INC-0.7%—Unchanged
24GPCRStructure Therapeutics INC-0.7%—Unchanged
25UPBUpstream Bio INC-0.7%—Unchanged
26430Terns Pharmaceuticals INC-0.7%—Unchanged
27ABVXAbivax Sa-adr-0.8%+60.00%Add
28HELPCybin INC-0.9%-10.49%Trim
29PTGXProtagonist Therapeutics INC-0.9%—Unchanged
30PRAXPraxis Precision Medicines I-1%—Unchanged
31PALIPalisade Bio INC-1.4%—Unchanged
32URGNUroGen Pharma Ltd.-1.4%—Unchanged
33CELCCelcuity INC-1.5%—Unchanged
34PTCTPtc Therapeutics INC-1.5%—Unchanged
35KYMRKymera Therapeutics INC-2%—Unchanged
36PCVXVaxcyte INC—NEWNew buy
37CRVSCorvus Pharmaceuticals INC—NEWNew buy
38CDTXCidara Therapeutics INC—EXITSold out
39DFTXDefinium Therapeutics INC—NEWNew buy
40IRDOpus Genetics INC—NEWNew buy
41CORTCorcept Therapeutics INC—NEWNew buy
42✓ Crescent Biopharma INC.—NEWNew buy
43BRD1EURMind Medicine Mindmed INC—EXITSold out
44SLNOEURSoleno Therapeutics INC—NEWNew buy
45ALLOAllogene Therapeutics INC—NEWNew buy
46RLMDRelmada Therapeutics INC—NEWNew buy
47✓ Crescent Biopharma INC.—EXITSold out
48OCULOcular Therapeutix INC—NEWNew buy
49ANTXAn2 Therapeutics INC—NEWNew buy
50ORICOric Pharmaceuticals INC—NEWNew buy

FAQ

What is Boxer Capital Management, LLC and what type of investor is it?
Boxer Capital Management, LLC is a investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-03-31), the firm manages a tracked equity portfolio valued at approximately $761.7M, spread across 54 disclosed positions.
What are Boxer Capital Management, LLC's largest equity positions?
Based on the latest 13F filing, Boxer Capital Management, LLC's top holdings by market value are: 1. Tango Therapeutics INC (TNGX) — $227.5M (29.9%) 2. Kodiak Sciences INC (KOD) — $51.9M (6.8%) 3. Revolution Medicines INC (RVMD) — $48.6M (6.4%) 4. Kymera Therapeutics INC (KYMR) — $27.4M (3.6%) 5. Celcuity INC (CELC) — $25.7M (3.4%)
What changes did Boxer Capital Management, LLC make in its most recent portfolio filing?
In the latest reported quarter, Boxer Capital Management, LLC made 29 notable position adjustments: 12 new positions were initiated, 12 existing holdings were added to, 2 positions were partially reduced, and 3 were completely exited. The largest of these moves: New buy: Vaxcyte INC (PCVX); New buy: Corvus Pharmaceuticals INC (CRVS); Sold out: Cidara Therapeutics INC (CDTX); New buy: Definium Therapeutics INC (DFTX); New buy: Opus Genetics INC (IRD)
What sectors does Boxer Capital Management, LLC focus on?
Boxer Capital Management, LLC is concentrated in the following sectors based on its current disclosed equity portfolio: • Health Care: 100.0%