NM

NEA Management Company, LLC

Sector-focusedContrarianQuality / disciplined sizing

Total reported value

$1.8B

Reporting period: 2026-03-31 · Number of holdings: 26

NEA Management Company, LLC disclosed 26 holdings in its latest 13F filing for the period ending 2026-03-31, with total reported value of $1.8B and a quarterly turnover rate of 52.0%.

Personality snowflake

Concentration
41.3
Portfolio Stability
51.95
Momentum/Contrarian
0
Sector conviction
100
Diversification
52
Sizing Uniformity
86.77

Recent moves

  • Add ACLXGBX

    0.0%　$151.1M

  • Trim CELC

    -35.4%　-$91.8M

  • Trim GOSS

    -94.5%　-$55.8M

  • Trim ZBIO

    +14.2%　-$49.3M

  • Add ORIC

    0.0%　$18.5M

  • Add GLUE

    0.0%　$5.9M

Holdings Map

New buyAddUnchangedTrim

Top 10 holdings by weight

Full holdings list this quarter

#TickerIssuerAsset SubclassWeightWeight ChangeShares Change4Q Trend
1ACLXGBXArcellx INCStock-Other19.88%+9.76%—
2CELCCelcuity INCStock-Other14.83%-3.15%-35.36%
3SGPSpyglass Pharma INCStock-Other10.89%+10.89%NEW
4TRVITrevi Therapeutics INCStock-Other8.97%+0.53%—
5SVRASavara INCStock-Other7.60%+0.08%—
6GLUEMonte Rosa Therapeutics INCStock-Other7.19%+1.04%—
7MBXMbx Biosciences INCStock-Other6.13%+0.32%—
8ZBIOZenas Biopharma INCStock-Other4.47%-2.05%+14.19%
9COURCoursera INCStock-Other4.26%-0.57%—
10AUPHAurinia Pharmaceuticals INCStock-Other3.34%+0.11%—
11ORICOric Pharmaceuticals INCStock-Other2.97%+1.25%—
12CRSPCRISPR Therapeutics AGStock-Healthcare2.86%+0.03%—
13PHATPhathom Pharmaceuticals INCStock-Other1.24%-0.42%—
14CVRXCvrx INCStock-Other1.09%+0.36%—
15KRROKorro Bio INCStock-Other0.84%+0.39%+18.99%
16ASNSUSDX4 Pharmaceuticals INCStock-Other0.76%+0.10%—
17CSBRChampions Oncology INCStock-Other0.56%-0.04%—
18BDTXBlack Diamond Therapeutics IStock-Other0.54%-0.01%—
19IVAInventiva SA - AdrStock-Other0.46%+0.11%—
20NKTXNkarta INCStock-Other0.43%+0.09%—
21LONALeonabio INCStock-Other0.27%+0.09%—
22✓ Senti Biosciences INCStock-Other0.17%-0.03%—
23MRKRMarker Therapeutics INCStock-Other0.12%——
24OKUROnkure Therapeutics Inc-aStock-Other0.11%+0.04%—
25GOSSGossamer Bio INCStock-Other0.02%-2.84%-94.47%
26IMAImagenebio INCStock-Other0.01%-0.01%—

Holding changes this quarter

NEA Management Company, LLC's most significant position changes for 2026-03-31: Sold out: Rhythm Pharmaceuticals INC (RYTM); New buy: Spyglass Pharma INC (SGP); Sold out: Synlogic INC (SYBX); Trim: Celcuity INC (CELC) — shares -35.36%; Trim: Gossamer Bio INC (GOSS) — shares -94.47%.

Position changes disclosed by NEA Management Company, LLC for the quarter ending 2026-03-31, including ticker, issuer, weight change, shares change, and action
#TickerIssuerWeight ChangeShares ChangeAction
1ACLXGBXArcellx INC+9.8%—Unchanged
2ORICOric Pharmaceuticals INC+1.3%—Unchanged
3GLUEMonte Rosa Therapeutics INC+1%—Unchanged
4TRVITrevi Therapeutics INC+0.5%—Unchanged
5KRROKorro Bio INC+0.4%+18.99%Add
6CVRXCvrx INC+0.4%—Unchanged
7MBXMbx Biosciences INC+0.3%—Unchanged
8AUPHAurinia Pharmaceuticals INC+0.1%—Unchanged
9IVAInventiva SA - Adr+0.1%—Unchanged
10ASNSUSDX4 Pharmaceuticals INC+0.1%—Unchanged
11LONALeonabio INC+0.1%—Unchanged
12NKTXNkarta INC+0.1%—Unchanged
13SVRASavara INC+0.1%—Unchanged
14OKUROnkure Therapeutics Inc-a0%—Unchanged
15CRSPCRISPR Therapeutics AG0%—Unchanged
16MRKRMarker Therapeutics INC——Unchanged
17BDTXBlack Diamond Therapeutics I0%—Unchanged
18IMAImagenebio INC0%—Unchanged
19✓ Senti Biosciences INC0%—Unchanged
20CSBRChampions Oncology INC0%—Unchanged
21PHATPhathom Pharmaceuticals INC-0.4%—Unchanged
22COURCoursera INC-0.6%—Unchanged
23ZBIOZenas Biopharma INC-2.1%+14.19%Add
24GOSSGossamer Bio INC-2.8%-94.47%Trim
25CELCCelcuity INC-3.2%-35.36%Trim
26RYTMRhythm Pharmaceuticals INC—EXITSold out
27SGPSpyglass Pharma INC—NEWNew buy
28SYBXSynlogic INC—EXITSold out

FAQ

What is NEA Management Company, LLC and what type of investor is it?
NEA Management Company, LLC is a investment manager that files SEC Form 13F quarterly, disclosing its U.S. public equity holdings to regulators. As of the most recent reporting period (2026-03-31), the firm manages a tracked equity portfolio valued at approximately $1.8B, spread across 26 disclosed positions.
What are NEA Management Company, LLC's largest equity positions?
Based on the latest 13F filing, NEA Management Company, LLC's top holdings by market value are: 1. Arcellx INC (ACLXGBX) — $349.7M (19.9%) 2. Celcuity INC (CELC) — $260.9M (14.8%) 3. Spyglass Pharma INC (SGP) — $191.5M (10.9%) 4. Trevi Therapeutics INC (TRVI) — $157.7M (9.0%) 5. Savara INC (SVRA) — $133.6M (7.6%)
What changes did NEA Management Company, LLC make in its most recent portfolio filing?
In the latest reported quarter, NEA Management Company, LLC made 7 notable position adjustments: 1 new positions were initiated, 2 existing holdings were added to, 2 positions were partially reduced, and 2 were completely exited. The largest of these moves: Sold out: Rhythm Pharmaceuticals INC (RYTM); New buy: Spyglass Pharma INC (SGP); Sold out: Synlogic INC (SYBX); Trim: Celcuity INC (CELC) — shares -35.36%; Trim: Gossamer Bio INC (GOSS) — shares -94.47%
What sectors does NEA Management Company, LLC focus on?
NEA Management Company, LLC is concentrated in the following sectors based on its current disclosed equity portfolio: • Health Care: 100.0%